OJBD  Vol.2 No.1 , March 2012
The Challenges of Diagnosing Disseminated Lyme Disease in a Patient with CLL
ABSTRACT
The diagnosis of Lyme disease may be a challenge in patients with Chronic Lymphocytic Leukemia. In relying on detection of antibodies in the serum for diagnosis we are presented with a problem in our patients with CLL in whom there is hypogammaglobulinemia secondary to B-cell malfunction. We suggest the use of PCR in aiding in diagnosis of Lyme disease in patients with CLL.

Cite this paper
S. Futuri, A. Malik and D. Shani, "The Challenges of Diagnosing Disseminated Lyme Disease in a Patient with CLL," Open Journal of Blood Diseases, Vol. 2 No. 1, 2012, pp. 14-15. doi: 10.4236/ojbd.2012.21003.
References
[1]   C. D. Schweighofer, et al., “Lyme Disease in a Patient with Chronic Lymphocytic Leukemia Mimics Leukemic Meningeosis,” Onkologie, Vol. 30, No. 11, 2007, pp. 564-566. doi:10.1159/000108920

[2]   M. Kalac, et al., “Central Nervous System Involvement of Previously Undiagnosed Chronic Lymphocytic Leukemia in a Patient with Neuroborreliosis,” International Journal of Hematology, Vol. 85, No. 4, 2007, pp. 323-325. doi:10.1532/IJH97.E0618

[3]   L. Cerroni, et al., “Specific Cutaneous Infiltrates of B-Cell Chronic Lymphocytic Leukemia (B-CLL) at Sites Typical for Borrelia burgdorferi Infection,” Journal of Cutaneous Pathology, Vol. 29, No. 3, 2002, pp. 142-147. doi:10.1034/j.1600-0560.2002.290303.x

 
 
Top