ABSTRACT Background: Methicillin-resistant Staphylococcus aureus (MRSA) is important nosocomial pathogen. Aim: In this paper, we determined the prevalence and the antibiotic susceptibility pattern of (MRSA) in a Sudanese surgical ward. Method: A total of 200 post-operative surgical specimens were collected from patients hospitalized in gastrointestinal tract (GIT) surgical ward in Ibn Sina hospital, Khartoum, Sudan and were subjected to MRSA screening and sensitivity test. Key findings: Out of 35 strains of Staphylococcus aureus isolated from surgical samples, 25 (71.4%) were found to be MRSA. Almost all MRSA strains were resistance to Methicillin, 96% to Ofloxacin, 92% to Pencillin G, 24% to Amikacin and 4% to Vancomycin. Cross-resistance was obviously detected. Conclusion: The present study detected alarming levels of S. aureus (MRSA) isolates, at the same time presence of high cross-resistance to other antibiotics.
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