JBNB  Vol.3 No.1 , January 2012
Particle Characteristics and Metal Release From Natural Rutile (TiO2) and Zircon Particles in Synthetic Body Fluids
ABSTRACT
Titanium oxide (rutile, TiO2) and zircon (ZrSiO4), known insoluble ceramic materials, are commonly used for coatings of implant materials. We investigate the release of zirconium, titanium, aluminum, iron, and silicon from different micron-sized powders of 6 powders of natural rutile (TiO2) and zircon (ZrSiO4) from a surface perspective. The investigation includes five different synthetic body fluids and two time periods of exposure, 2 and 24 hours. The solution chemicals rather than pH are important for the release of zirconium. When exceeding a critical amount of aluminum and silicon in the surface oxide, the particles seem to be protected from selective pH-specific release at neutral or weakly alkaline pH. The importance of bulk and surface composition and individual changes between different kinds of the same material is elucidated. Changes in material properties and metal release characteristics with particle size are presented for zircon.

Cite this paper
Y. Hedberg, J. Hedberg and I. Wallinder, "Particle Characteristics and Metal Release From Natural Rutile (TiO2) and Zircon Particles in Synthetic Body Fluids," Journal of Biomaterials and Nanobiotechnology, Vol. 3 No. 1, 2012, pp. 37-49. doi: 10.4236/jbnb.2012.31006.
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