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 IJOC  Vol.1 No.4 , December 2011
Vilsmeier Haack Adducts as Effective Reagents for Regioselective Nitration of Aromatic Compounds under Conventional and Non-Conventional Conditions
Abstract: Nitration of aromatic Compounds is triggered by Vilsmeier-Haack reagent (DMF/POCl3) or (DMF/SOCl2) in the presence of KNO3 or NaNO2 under conventional and non-conventional conditions. The reactions af- forded corresponding Nitro derivatives in very good yield with high regioselectivity. The results obtained in non-conventional methods (Micro wave irradiation, Grinding, Sonication) are comparable with those ob- tained under conventional conditions, but the reaction times of former conditions are substantially shorter than that of the latter.
Cite this paper: nullK. Rajanna, M. Kumar, P. Venkanna, S. Ramgopal and M. Venkateswarlu, "Vilsmeier Haack Adducts as Effective Reagents for Regioselective Nitration of Aromatic Compounds under Conventional and Non-Conventional Conditions," International Journal of Organic Chemistry, Vol. 1 No. 4, 2011, pp. 250-256. doi: 10.4236/ijoc.2011.14036.
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