ABSTRACT Pseudomonas aeruginosa bacteremia rarely occurs in non-immunocompromised adults and can be difficult to be treated. We report a case of 35-year-old woman who presented with respiratory distress, fever and skin lesions. There was pleural effusion in chest radiograph, and CT scan of thorax showed necrotizing pneumonia and loculated empyema. Among the cultures of blood, empyema, sputum and the skin nodules aspirates, all were positive for Pseudomonas aeruginosa. The patient was treated with ciprofloxacin, amikacin and then pleural decortications. Laboratory tests failed to reveal any immunological deficits. After a period of 21 days of antibiotic therapy, the patient was discharged from hospital with a good condition.
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