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 OJO  Vol.1 No.2 , December 2011
Eosinophilic Granuloma Arising from the Sacrum: A Case Report
Abstract: Introduction: Osseous eosinophilic granulomas commonly occur in the skull, pelvis, vertebrae, mandible, and ribs. However, the eosinophilic granuloma in the sacrum is rare. Case presentation: We present the case of a 13-year-old Japanese boy, who presented with left low-back pain, and was diagnosed with eosinophilic granuloma arising in the sacrum. Computed tomography (CT) and magnetic resonance imaging demonstrated an osteolytic lesion with interruption of the cortex, and signal intensity changes at the left sacral body and wing. Histologic examination indicated an eosinophilic granuloma. Two years after CT-guided biopsy, the tumor had spontaneously healed completely, with no residual pain.Conclusion: The present case was eosiophilic granuloma arising from the rare site of sacrum. The tumor was completely remodeled two years after biopsy.
Cite this paper: nullY. Kasukawa, N. Miyakoshi, M. Hongo, S. Ando, Y. Ishikawa and Y. Shimada, "Eosinophilic Granuloma Arising from the Sacrum: A Case Report," Open Journal of Orthopedics, Vol. 1 No. 2, 2011, pp. 5-8. doi: 10.4236/ojo.2011.12002.
References

[1]   Plasschaert F, Craig C, Bell R, Cole WG, Wunder JS, Alman BA: Eosinophilic granuloma: a different behavior in children than in adults. J Bone Joint Surg Br. 2002, 84: 870-872.

[2]   Muscolo DL, Slullitel G, Ranalletta M, Aponte-Tinal LA, Ayerza MA: Spontaneous remission of massive solitary eosinophilic granuloma of the femur. J Pediatr Orthop 2003, 23: 763-765.

[3]   Otani S, Ehrlich JG: Solitary granuloma of bone simulating primary neoplasm. Am J Pathol 1940, 16: 479-490.

[4]   Lichtenstein L, Jaffe HL: Eosinophilic granuloma of bone. With report of a case. Amer J Pathol 1940, 16: 595–604.

[5]   Grundy P, Ellis R: Hisiocytosis X: a review of the etiology, pathology, staging, and therapy. Med Pediatr Oncol 1986, 14: 45-50.

[6]   David R, Oria RA, Kumar R, Singleton EB, Lindell MM, Shirkhoda A, Madewell JE: Radiologic features of eosinophilic granuloma of bone. AJR Am J Roentgenol 1989, 153: 1021-1026.

[7]   Still MA, Kransdorf MJ, Devaney KO: Langerhans cell histiocytosis of bone. Radiographics 1992, 12: 801-823.

[8]   Azouz EM, Saigal G, Rodriguez MM, Podda A: Langerhans’ cell histiocytosis: pathology, imaging and treatment of skeletal involvement. Pediatr Radiol 2005, 35: 103-115.

[9]   Hoover KB, Rosenthal DI, Mankin H: Langerhans cell histiocytosis. Skeletal Radiol 2007, 36: 95-104.

[10]   Monroc M, Ducou le Pointe H, Haddad S, Josset P, Montagne JP: Soft tissue signal abnormality associated with eosinophilic granuloma. Correlation of MR imaging with pathologic findings. Pediatr Radiol 1994, 24: 328-332.

[11]   Cardon T, Hachulla E, Flipo RM, Chastanet P, Rose C, Deprez X, Delcambre B, Devulder B: Percutaneous vertebroplasty with acrylic cement in the treatment of a Langerhans cell vertebral histiocytosis. Clin Rheumatol 1994, 13: 518-21.

[12]   Leonidas JC: Langerhans’ cell histiocytosis. In Radiology: diagnosis, imaging, intervention. Volume 5. Edited by Taveras JM, Ferrucci JM. Philadelphia: Lippincott; 1990.

[13]   Johansson L, Larsson LG, Damber L: A cohort study with regard to the risk of haematological malignancies in patients treated with X-rays for benign lesions in the locomotor system. Acta Oncol 1995, 34: 721-726.

[14]   Green NE, RobertsonWW Jr,Kilroy AW: Eosinophilic granuloma of the spine with associated neural deficit: report of three cases. JBJS 1980, 62A: 1198-1202.

[15]   Silberstein MJ, Sundaram M, Akbarnia B, Luisiri A, McGuire M: Eosinophilic granuloma of the spine. Orthopedics 1985, 8: 267-274.

[16]   Ando A, Hatori M, Hosaka M, Hagiwara Y, Kita A, Itoi E: Eosinophilic granuloma arising from the pelvis in children: A report of three cases. Upsala J Med Sci 2008, 113: 209-216.

 
 
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