ABSTRACT Drug carrier biocompatible and biodegradable nanoparticles of about 15 nm were prepared by solvent evaporation technique from star-shaped poly(D,L-lactide) synthesized using dipentaerythritol as core and Tin (II) ethylhexanoate as catalyst.
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nullM. Marini, "Preparation of Star-Shaped Polylactic Acid Drug Carrier Nanoparticles," Materials Sciences and Applications, Vol. 1 No. 1, 2010, pp. 36-38. doi: 10.4236/msa.2010.11007.
 U. Schröder and B. Sabel, “Nanoparticles, a Drug Carrier System to Pass the Blood-Brain Barrier Permit Central Analgesic Effects of i.v. Dalargin Injections,” Brain Research, Vol. 710, 1996, pp. 121-124.
 X. Zhou and E. Huang, “Targeted Delivery of DNA by Liposomes and Polymers,” Journal of Controlled Release, Vol. 19, 1992, pp. 269-274.
 A. Vila, A. Sanchez, M. Tobio, P. Calvo and M. J. Alonso, “Design of Biodegradable Particles for Protein Delivery,” Journal of Controlled Release, Vol. 78, 2002, pp. 15-24.
 A. Rouzes, M. Leonard, A. Durand and E. Dellacherie, “Influence of Polymeric Surfactants on the Properties of Drug-Loaded PLA Nanospheres,” Coloids and Surfaces B: Biointerfaces, Vol. 32, 2003, pp. 125-135.
 S. Desgouilles, C. Vauthier, D. Bazile, J. Vacus, J. L. Grossiord, M. Veillard and P. Couvreur, “The Design of Nanoparticles Obtained by Solvent Evaporation: A Comprehensive Study,” Langmuir, Vol. 19, 2003, pp. 9504- 9510.
 A. S. Karikari, W. F. Edwards, J. B. Mecham and T. E. Long, “Influence of Peripheral Hydrogen Bonding on the Mechanical Properties of Photo-Cross-Linked Star-Shap- ed Poly(D,L-lactide) Networks,” Biomacromolecules, Vol. 6, 2005, pp. 2866-2874.
 W. Radke, K. Rode, A. V. Gorshov and T. Biela, “Chromatographic Behaviour of Functionalized Star-Shaped Poly(lactide)s under Critical Conditions of Adsorption. Comparison of Theory and Experiment,” Polymer, Vol. 46, 2005, pp. 5456-5465