Back
 JTST  Vol.7 No.2 , May 2021
Preparation and Characterization of the Electrospun Alginate Nanofibers
Abstract: Due to some intrinsic functional behavior of alginate, many potential applications in the healthcare industry especially in wound care sector are observed. Many researches have been carried out to develop potential biomedical biocompatible products in different forms from alginate fibres. Alginate nanofibres were prepared from sodium alginate polymer with the presence of poly-(ethylene oxide) (PEO), a small amount of Triton ×100 surfactant. A homogeneous spinning solution was prepared for producing Na-alginate/PEO nanofibers in electrospinning device. Nanofibres were produced by electrospinning from 70:30 and 80:20 Na-alginate/PEO of 4% solution. After a series of trials, the electrospinning parameters were optimized at 16 cm working distance, 0.4 mL/h flow rate and 10.5 kV applied voltage. The results show that the 4 wt% of 70:30 Na-alginate/PEO solution with 0.5 wt% Triton × 100 surfactant yielded smooth and stable electrospinning. The surface morphology of the fibres was investigated using Scanning Electron Microscope (SEM) and found the uniform fibres with an average diameter of 124 nm containing few thick or spindle-like fibres. FTIR investigation identified the chemical structure and molecular changes that occurred in the fibers.
Cite this paper: Hossain, M. and Rahman, M. (2021) Preparation and Characterization of the Electrospun Alginate Nanofibers. Journal of Textile Science and Technology, 7, 91-100. doi: 10.4236/jtst.2021.72008.
References

[1]   Bhattarai, N., Li, Z., Edmondson, D. and Zhang, M. (2006) Alginate-Based Nanofibrous Scaffolds: Structural, Mechanical, and Biological Properties. Advanced Materials, 18, 1463-1467.
https://doi.org/10.1002/adma.200502537

[2]   Kong, Q., Yu, Z., Ji, Q. and Xia, Y. (2009) Electrospinning of Sodium Alginate with Poly(ethylene oxide), Gelatin and Nanometer Silver Colloid. Materials Science Forum, 610-613, 1188-1191.
https://doi.org/10.4028/www.scientific.net/MSF.610-613.1188

[3]   Doshi, J. and Reneker, D.H. (1993) Electrospinning Process and Applications of Electrospun Fibers. Conference Record, Industry Applications Society, IEEE-IAS Annual Meeting, Vol. 3, 1698-1703.

[4]   Varaprasad, K., Jayaramudu, T., Kanikireddy, V., Toro, C. and Sadiku, E.R. (2020) Alginate-Based Composite Materials for Wound Dressing Application: A Mini Review. Carbohydrate Polymers, 236, Article ID: 116025.
https://doi.org/10.1016/j.carbpol.2020.116025

[5]   Yeung, R.A. and Kennedy, R.A. (2019) A Comparison of Selected Physico-Chemical Properties of Calcium Alginate Fibers Produced Using Two Different Types of Sodium Alginate. The Journal of the Mechanical Behavior of Biomedical Materials, 90, 155-164.
https://doi.org/10.1016/j.jmbbm.2018.10.011

[6]   Qin, Y. (2008) Alginate Fibres: An Overview of the Production Processes and Applications in Wound Management. Polymer International, 57, 171-180.
https://doi.org/10.1002/pi.2296

[7]   Coşkun, G., Karaca, E., Ozyurtlu, M., Özbek, S., Yermezler, A. and Çavuşoǧlu, I. (2014) Histological Evaluation of Wound Healing Performance of Electrospun Poly-(vinyl alcohol)/Sodium Alginate as Wound Dressing in Vivo. Bio-Medical Materials and Engineering, 24, 1527-1536.
https://doi.org/10.3233/BME-130956

[8]   Bhattarai, N. and Zhang, M. (2007) Controlled Synthesis and Structural Stability of Alginate-Based Nanofibers. Nanotechnology, 18, Article ID: 455601.
https://doi.org/10.1088/0957-4484/18/45/455601

[9]   Tucker, N., Hofman, K., Stanger, J., Staiger, M., Hamid, N.A. and Torres, P.L. (2011) The History of the Science and Technology of Electrospinning from 1600 to 1995. Journal of Engineered Fibers and Fabrics, 7, 63-73.
https://doi.org/10.1177/155892501200702S10

[10]   Xue, J., Wu, T., Dai, Y. and Xia, Y. (2019) Electrospinning and Electrospun Nanofibers: Methods, Materials, and Applications. Chemical Reviews, 119, 5298-5415.
https://doi.org/10.1021/acs.chemrev.8b00593

[11]   Kleivaite, V. and Milašius, R. (2018) Electrospinning—100 Years of Investigations and Still Open Questions of Web Structure Estimation. Autex Research Journal, 18, 398-404.
https://doi.org/10.1515/aut-2018-0021

[12]   Islam, M.S., Ang, B.C., Andriyana, A. and Afifi, A.M. (2019) A Review on Fabrication of Nanofibers via Electrospinning and Their Applications. SN Applied Sciences, 1, 1-16.
https://doi.org/10.1007/s42452-019-1288-4

[13]   Li, L. and Lo Hsieh, Y. (2006) Chitosan Bicomponent Nanofibers and Nanoporous Fibers. Carbohydrate Research, 341, 374-381.
https://doi.org/10.1016/j.carres.2005.11.028

[14]   Mirtič, J., Balažic, H., Zupančič, Š. and Kristl, J. (2019) Effect of Solution Composition Variables on Electrospun Alginate Nanofibers: Response Surface Analysis. Polymers (Basel), 11, 692.
https://doi.org/10.3390/polym11040692

[15]   Mincheva, R., Manolova, N., Paneva, D. and Rashkov, I. (2005) Preparation of Polyelectrolyte-Containing Nanofibers by Electrospinning in the Presence of a Non-Ionogenic Water-Soluble Polymer. Journal of Bioactive and Compatible Polymers, 20, 419-435.
https://doi.org/10.1177/0883911505057447

[16]   Saquing, C.D., et al. (2013) Alginate-Polyethylene Oxide Blend Nanofibers and the Role of the Carrier Polymer in Electrospinning. Industrial & Engineering Chemistry Research, 52, 8692-8704.
https://doi.org/10.1021/ie302385b

[17]   Hossain, M.F., Rahman, M. and Nur, M.G. (2017) Ageing Effects of Na-Alginate/ PEO Spinning Solution on Electrospinnability and Morphology of Nanofibres. European Scientific Journal, 13, 56.
https://doi.org/10.19044/esj.2017.v13n9p56

[18]   Hu, C., Gong, R.H. and Zhou, F.L. (2015) Electrospun Sodium Alginate/Polyethylene Oxide Fibers and Nanocoated Yarns. International Journal of Polymer Science, 2015, Article ID: 126041.
https://doi.org/10.1155/2015/126041

[19]   Lu, J.W., Zhu, Y.L., Guo, Z.X., Hu, P. and Yu, J. (2006) Electrospinning of Sodium Alginate with Poly(ethylene oxide). Polymer (Guildf.), 47, 8026-8031.
https://doi.org/10.1016/j.polymer.2006.09.027

[20]   Nie, H., et al. (2009) Effect of Poly(ethylene oxide) with Different Molecular Weights on the Electrospinnability of Sodium Alginate. Polymer (Guildf.), 50, 4926-4934.
https://doi.org/10.1016/j.polymer.2009.07.043

[21]   Jeong, S.I., Krebs, M.D., Bonino, C.A., Khan, S.A. and Alsberg, E. (2010) Electrospun Alginate Nanofibers with Controlled Cell Adhesion for Tissue Engineering. Macromolecular Bioscience, 10, 934-943.
https://doi.org/10.1002/mabi.201000046

 
 
Top