SS  Vol.12 No.4 , April 2021
Surgical Management of a Case of Splenic Necrosis at Point G Chu in Bamako
Abstract: Splenic infarction is a rare condition (1/500,000 and 1/100,000) but potentially fatal. The prognosis depends on the diagnostic delay and above all on the speed of treatment. It usually occurs in a particular area such as myeloproliferative syndrome, sickle cell anemia, thalassemia etc. The objective of this work was to report a clinical case of necrosis of the spleen.

1. Introduction

Splenic infarction is a little known condition with a prevalence of 1/500,000 and 1/100,000 cases, but potentially fatal. This mortality is mainly linked to diagnostic and therapeutic delay, as well as to the risks related to the site and the seriousness of the underlying pathology [1].

It usually occurs in an abnormally enlarged spleen, either as a result of a myeloproliferative syndrome or by vascular occlusion as in sickle cell anemia, thalassemia [2].

The repetition of these infarcts can considerably decrease the functional capacity of the spleen. It causes alteration in its roles of filtering and removing blood cells and storing platelets, the risk of serious infection from secondary immune deficiency.

The diagnosis is suggested in cases of hemorrhagic shock associated with abdominal pain in the absence of any trauma. This diagnosis is based on the results of an abdominal ultrasound and CT scan.

Splenic infarction may be clinically silent or may manifest as severe pain in the left hypochondrium [3].

The treatment is essentially surgical (splenectomy).

The objective of this work was to report a clinical case of spleen necrosis in the “A” surgical department at the Point G University Hospital.

2. Clinical Observation

We report a clinical case of spleen necrosis. This was a 28-year-old patient, a trader by profession, with known sickle cell disease with SC without any particular surgical history. He was referred to us by his doctor brother for abdominal pain.

On clinical examination we found conjunctival-palmoplantar pallor, abdominal pain evolving for 3 days, located in the left flank, of strong intensity, diffuse irradiation, without calming factors or triggering factors associated with an unquantified fever. Palpation found a mass extending from the left hypochondrium to the left iliac fossa, painful, fixed, firm, measuring 15 cm transverse axis and 25 cm cranio-caudal axis. The examination of the other organs was unremarkable.

The result of the abdominopelvic ultrasound was in favor of a heterogeneous spleen with irregular contours, surrounded by a large echogenic fluid collection of 175 × 166 mm and a sub-capsular hemorrhage with splenic necrosis.

The appearance suggestive of a spontaneous rupture of the spleen with probably involvement of the splenic artery and homogeneous hepatomegaly without focal lesion was found on CT.

An emergency preoperative workup including CBC, rhesus group, serum creatinine, blood sugar was performed.

Under general anesthesia with orotracheal intubation, intraoperatively we discovered a large mass of fluid content whose puncture brought back pus chocolate, necrosis of the spleen with a splenic parenchyma completely detached from its vessels. The surgical procedure performed was manual removal of the splenic parenchyma, ligation of the splenic vessels in the rear omentum cavity, resection of the capsule, placement of a tubular drain in the splenic compartment.

The culture of the sample fluid was sterile. The histology of the surgical specimen did not find any tumor. The pneumo 23 vaccine was administered to the patient.

In the immediate postoperative follow-up, the patient presented with a picture of abdominal distension on D5. The ultrasound showed a large peritoneal effusion in favor of ascites. The evacuating puncture emptied 500 ml of citrus yellow liquid. Discharge was authorized on D15 with a request for consultation at the sickle cell research and control center (CRLD).

3. Discussion

Non-traumatic rupture of the spleen (spontaneous) is a rare but classic feature of splenic-tropic disease. In the literature, the etiology of splenic infarction is thrombosis of the vein and or splenic artery following infection either with N. meningitidis, EBV, HIV and or acute leukemia, lymphoma, to a chronic myeloproliferative syndrome, to vascular tumors, to hemopathies and the taking of certain drugs such as estrogen-progestogens. In the work of Philippe C et al., the splenic infarction was linked to a thrombosis of the splenic vein [4].

Sickle cell disease with probably thrombosis of the splenic vein was found as an etiological factor in our patient. In the literature, pathologies such as sickle cell anemia are the second cause of splenic infarction and affect patients under 40 years of age [5].

The origin of endemic malaria should be a reason to seek infection with plasmodium vivax which is one of the etiologies

SI is symptomatic in 60% to 100% [6], inaugural abdominal pain has been reported in the literature. These are diffuse or localized pain in the left hypochondrium, pelvic pain, fever and/or splenomegaly [7] [8].

Kehrs sign is less found [9]. It is a left scapular irradiation pain reflecting diaphragmatic irritation associated with peritoneal effusion. Abdominal pain syndrome sets in a few days before the rupture. This observation was made in our case, 72 hours before admission. The rupture is rarely indicative of the pathology, it most often occurs in a known area [10].

Splenic infarction alone is not an indication for surgery. Treatment of splenic infarction is symptomatic. Usually, healing occurs within one to two weeks. Complications are noted in about 20% of cases, most often in the context of infarction secondary to vascular occlusion. It may be a ruptured spleen with subcapsular hemorrhage or hemoperitoneum, a splenic abscess or pseudocyst formation which are the indications for surgery [5]. The histology of the surgical specimen does not find any tumor cells that were palpable on the surgical specimen as shown in Figure 1. This observation was made in our study.

Figure 1. Appearance of the splenic parenchyma postoperatively. Source: Department of surgery A of the CHU of POINT G.

The prognosis for splenic infarction depends on the underlying pathology.

4. Conclusion

Splenic infarcts are of a wide variety of conditions, sometimes serious, and should always be investigated. Complications and prognosis appear to be related to the underlying pathology.

Cite this paper: Sissoko, M. , Coulibaly, M. , Koumaré, S. , Sacko, O. , Keïta, S. , Keita, S. , Diallo, S. , Soumaré, L. , Traoré, A. , Koïta, A. , Camara, M. , Camara, A. , Dicko, H. , Sangaré, D. and Sanogo, Z. (2021) Surgical Management of a Case of Splenic Necrosis at Point G Chu in Bamako. Surgical Science, 12, 103-106. doi: 10.4236/ss.2021.124012.

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