[1]
|
Stewart, J.H. and Donald V.L. (2000) Germanium, Tin, and Copper. Patty’s Toxicology. John Wiley & Sons, Inc., 51-54. https://doi.org/10.1002/0471435139.tox033
|
[2]
|
Keith, L.S., Faroon, O.M., Maples-Reynolds, N. and Fowler, B.A. (2015) Germanium-Handbook on the Toxicology of Metals. Chapter 37. Handbook on the Toxicology of Metals, 4th Edition, 799-816. https://doi.org/10.1016/B978-0-444-59453-2.00037-8
|
[3]
|
Song, C.L., Ji, C. and Jing, X.D. (2005) Advance in Physical and Chemical Properties of Germanium and Nutrition Functions in Animals. Chinese Journal of Animal Science, 41, 64-66.
|
[4]
|
Rosenfeld, G. (1954) Studies of the Metabolism of Germanium. Archives of Biochemistry and Biophysics, 48, 84-94. https://doi.org/10.1016/0003-9861(54)90308-2
|
[5]
|
Dimartino, M.J., Lee, J.C., Badger, A.M., Muirhead, K.A., Mirabelli, C.K. and Hanna, N. (1986) Antiarthritic and Immunoregulatory Activity of Spirogermanium. Journal of Pharmacology & Experimental Therapeutics, 236, 103-110.
|
[6]
|
Burley, R.W., Evans, A.J. and Pearson, J.A. (1993) Molecular Aspects of the Synthesis and Deposition of Hens’ Egg Yolk with Special Reference to Low Density Lipoprotein. Poultry science, 72, 850-855. https://doi.org/10.3382/ps.0720850
|
[7]
|
Kobayashi, A. and Ogra, Y. (2009) Metabolism of Tellurium, Antimony and Germanium Simultaneously Administered to Rats. The Journal of Toxicological Sciences, 34, 295-303. https://doi.org/10.2131/jts.34.295
|
[8]
|
Krystek, P. and Ritsema, R. (2004) Analytical Product Study of Germanium-Containing Medicine by Different ICP-MS Applications. Journal of Trace Elements in Medicine and Biology, 18, 9-16. https://doi.org/10.1016/j.jtemb.2004.04.003
|
[9]
|
Kim, E., Jeon, Y., Kim, D.Y., Lee, E. and Hyun, S.H. (2015) Antioxidative Effect of Carboxyethylgermanium Sesquioxide (Ge-132) on Ivm of Porcine Oocytes and Subsequent Embryonic Development after Parthenogenetic Activation and IVF. Theriogenology, 84, 226-236. https://doi.org/10.1016/j.theriogenology.2015.03.006
|
[10]
|
Nakada, Y., Kosaka, T., Kuwabara, M., Tanaka, S., Sato, K. and Koide, F. (1993) Effects of 2-Carboxythylgerumanium Sesquioxide (Ge-132) as an Immunological Modifier of Post-Surgical Immunosuppression in Dogs. Journal of Veterinary Medical Science, 55, 795-799. https://doi.org/10.1292/jvms.55.795
|
[11]
|
Ikemoto, K., Kobayashi, M., Fukumoto, T., Morimatsu, M., Pollard, R.B. and Suzuki, F. (1996) 2-Carboxyethylgermanium Sesquioxide, a Synthetic Organogermanium Compound, as an Inducer of Contrasuppressor T Cells. Experientia, 52, 159-166. https://doi.org/10.1007/BF01923363
|
[12]
|
Suzuki, F., Brutkiewicz, R.R. and Pollard, R.B. (1986) Cooperation of Lymphokine(s) and Macrophages in Expression of Antitumor Activity of Carboxyethylgermanium Sesquioxide (Ge-132). Anticancer Research, 6, 177-182.
|
[13]
|
Nakamura, T., Nagura, T., Sato, K. and Ohnishi, M. (2012) Evaluation of the Effects of Dietary Organic Germanium, Ge-132, and Raffinose Supplementation on Caecal Flora in Rats. Bioscience of Microbiota Food & Health, 31, 37-45. https://doi.org/10.12938/bmfh.31.37
|
[14]
|
Badger, A.M., Schwartz, D.A., Picker, D.H., Dorman, J.W., Bradley, F.C., Cheeseman, E.N., Dimartino, M.J., Hanna, N. and Mirabelli, C.K. (1991) Cheminform Abstract: Antiarthritic and Suppressor Cell Inducing Activity of Azaspiranes: Structure-Function Relationships of a Novel Class of Immunomodulatory Agents. Journal of Medicinal Chemistry, 22, 2963-2970.
|
[15]
|
Badger, A.M. and DiMartino, M.J. (1988) Immunomodulatory Activity and Non-Specific Suppressor Cell Generation by Spirogermanium in Murine and Rat Models of Cell-Mediated Immunity. Immunopharmacology, 16, 33-43. https://doi.org/10.1016/0162-3109(88)90048-3
|
[16]
|
Lukevics, E. and Ignatovich, L. (2003) Biological Activity of Organogermanium Compounds. Cheminform, 34, 279-295. https://doi.org/10.1002/chin.200345272
|
[17]
|
Badger, A.M., Mirabelli, C.K. and Dimartino, M. (1985) Generation of Suppressor Cells in Normal Rats by Treatment with Spirogermanium, a Novel Heterocyclic Anticancer Drug. Immunopharmacology, 10, 201-207. https://doi.org/10.1016/0162-3109(85)90026-8
|
[18]
|
Badger, A.M., Dimartino, M.J., Schmitt, T.C., Swift, B.A. and Mirabelli, C.K. (1987) Suppressor Cell Induction by the Anticancer Drug Spirogermanium. International Journal of Immunopharmacology, 9, 621-630. https://doi.org/10.1016/0192-0561(87)90129-9
|
[19]
|
Hill, B.T. and Whelan, R.D. (1986) Spirogermanium—A Novel Antitumour Agent Expressing a Lack of Cross-Resistance in Vitro with a Range of ‘Standard’ Antitumour Drugs. Investigational New Drugs, 4, 359-365. https://doi.org/10.1007/BF00173508
|
[20]
|
Schauss, A.G. (1991) Nephrotoxicity and Neurotoxicity in Humans from Organogermanium Compounds and Germanium Dioxide. Biological Trace Element Research, 29, 267-280.
|
[21]
|
Lin, H., Wei, P.J., Gu, P.K. and Jin, Z.G. (1994) Protective Effect of Germanium-Aminoacid on Rat Myocardial Cells Inculture to Oxygen and. Journal of Shanghai Second Medical University, 8, 62-68.
|
[22]
|
Ismail, D.A. and Noaman, E. (2007) Synthesis and Antitumour Activity of Four Germanium Amino Acid Complexes. Egyptian Journal of Chemistry, 50, 29-37.
|
[23]
|
Wang, R., Shi, P., Hu, B., Shen, Y., Wang, Z. and Li, C. (1998) Radiosensitizing Effects of Amino-Acid Germanium Compounds on Tumor Radiotherapy. Trace Elementsence, 5, 42-44.
|
[24]
|
Chen, H.Z., Sun, C., Yu, A.Y. and Jin, Z.J. (1990) Antitumor Effect of Lysine Germanium. Proceedings of Academic Conference on Nutrition and Oncology of China Nutrition Society.
|
[25]
|
Chen, H.Z., Sun, C., Yu, A.Y. and Jin, Z.J. (1990) The Promotional Effect of Lysine Germanium on Immune Function. Proceedings of Academic Conference on Nutrition and Oncology of China Nutrition Society.
|
[26]
|
Ge, X.M., Zhao, F.J., Guo, J.S., Cheng, H.Z., Zhu, P.M. and Ji, Y.S. (1994) Antitumor Activity and Immunological Effect of Alanine-Germanium. Journal of Preventive Medicine of Chinese People’s Liberation Army, 12, 341-344.
|
[27]
|
Gao, S.Y. (1990) Clinical Application of the Amino Acid Germanium Oxide. Studies of Trace Elements and Health, 3, 2.
|
[28]
|
Zhao, F.J., Guo, J.S., Ji, Y.S., Nie, Z., Chen, H.Z. and Sun, W. (1990) Research of the Anticancer Activity of the Amino Acid Germanium Oxide (AGO-GA). Proceedings of Academic Conference on Nutrition and Oncology of China Nutrition Society.
|
[29]
|
Zheng, H.P. (2011) Physiological Function of Organic Germanium and Its Application in Food. Studies of Trace Elements and Health, 28, 65-67.
|
[30]
|
Hess, B., Raisin, J., Zimmermann, A., Horber, F., Bajo, S., Wyttenbach, A. and Jaeger, P. (1993) Tubulointerstitial Nephropathy Persisting 20 Months after Discontinuation of Chronic Intake of Germanium Lactate Citrate. American Journal of Kidney Diseases, 21, 548-552. https://doi.org/10.1016/S0272-6386(12)80403-3
|
[31]
|
Lu, S.L., Tang, J.X. and Deng, L.S. (1997) Effects of Germanium Citrate on the Immunogenic Function of Mice. Guangdong Trace Elements Science, 4, 21-23.
|
[32]
|
Lu, S.L., Zhang, G.L., Zhong, H.L. and Ren, G.Y. (1998) An Experimental Study on Antitumor Effect of Germanium Citrate. Guangdong Trace Elements Science, 5, 44-46.
|
[33]
|
Van, S.J.I., Stricker, B.H., Schipper, M.E., Bruijn, W., Smet, P.A. and Esseveld, M.R. (1991) Toxic Damage of Kidney, Liver and Muscle Attributed to the Administration of Germanium-Lactate-Citrate. Nederlands Tijdschrift Voor Geneeskunde, 135, 1134-1137.
|
[34]
|
Zhang, S.G., Ni, J.Z. and Nie, Y.X. (1990) The Synthetic Properties and Anticancer Activity of Ge-162 (Abstract). Studies of Trace Elements and Health, 3, 11.
|
[35]
|
Tang, B.H., Mo, Z.S. and Huang, S.D. (1994) Studies on Germanium Yeast. Journal of Preventive Medicine of Chinese People’s Liberation Army, 12, 179-183.
|
[36]
|
Liu, Y.F., Shi, J.Y., Tang, R.H. and Zhu, H.T. (1984) The Promotional Effect of Germanium on the Growth of Pear-Shaped Tetraphymena Cells and Beer Yeast. Chinese Science Bulletin, 29, 235-237.
|
[37]
|
Jang, J.J., Lee, S.J., Cho, K.J. and Kim, S.H. (1989) Lack of Modifying Effect of Germanium in Rat Hepatic Foci Initiated by Diethylnitrosamine Followed by D-Galactosamine Treatment. Journal of the Korean Cancer Association, 21, 7-11.
|
[38]
|
Zhang, Y., Wang, B. and Zhang, G. (2004) Study of Anti-Tumor and Mechanism of Organogermanium Poly-Derivatinmves. Carcinogenesis Teratogenesis & Mutagenesis, 16, 39-42.
|
[39]
|
Yang, F., Gong, L., Jin, H., Pi, J., Bai, H., Wang, H., Cai, H., Yang, P. and Cai, J. (2015) Chrysin-Organogermanium (IV) Complex Induced Colo205 Cell Apoptosis-Associated Mitochondrial Function and Anti-Angiogenesis. Scanning, 37, 246-257. https://doi.org/10.1002/sca.21205
|
[40]
|
Lin, C.H., Chen, T.J. and Chen, S.S. (2009) Functional Changes on Ascending Auditory Pathway in Rats Caused by Germanium Dioxide Exposure: An Electrophysiological Study. Toxicology, 256, 110-117.
|
[41]
|
Heoun, B.D., Jin, J.T.U.S. and Kang, J.K. (2007) Germanium-Fortified Yeast Activates Macrophage, Nk Cells and B Cells and Inhibits Tumor Progression in Mice. Korean Journal of Microbiology & Biotechnology, 35, 118-127.
|
[42]
|
Wang, B.G., Zhang, G.Y., Zhao, L.Y. and Liu, Y. (2002) Inhibiting Effect of Organic Germanium Poly-Acid Derivative on S180 Cells. Journal of Xi’an Jiaotong University, 23, 550-551.
|
[43]
|
Chen, Y. and Shi, Y. (1994) Inhibitory Effect of Ge-132 on the Tumor Lesion of Marek, Disease and Its Mechanism. Chinese Journal of Veterinary Science, 14, 18-22.
|
[44]
|
Kang, K.S., Yun, J.W., Yoon, B.S., Lim, Y.K. and Lee, Y.S. (2001) Preventive Effect of Germanium Dioxide on the Inhibition of Gap Junctional Intercellular Communication by TPA. Cancer Letters, 166, 147-153. https://doi.org/10.1016/S0304-3835(01)00446-3
|
[45]
|
Liu, C.H., Yao, F.Y., Sun, F.Y., Jiang, J.L. and Xiao, C. (2016) Study on the Inhibition Effect of Caffeic Acid Germanium on the U14 Tumor in Mice and the Cell Apoptosis Mechanisms. Heilongjiang Animal Science & Veterinary Medicine, 11, 178-180.
|
[46]
|
Kobayashi, A. and Ogra, Y. (2009) Metabolism of Tellurium, Antimony and Germanium Simultaneously Administered to Rats. Journal of Toxicological Sciences, 34, 295-303. https://doi.org/10.2131/jts.34.295
|
[47]
|
Wang, Y.X. and Xiao, C. (2006) Research and Progress of Organic Germanium. Jiangxi Journal of Medical Laboratory Sciences, 24, 252-254.
|
[48]
|
Oh, C., Li, M., Kim, E.H., Park, J.S., Lee, J.C. and Ham S.W. (2011) Cheminform Abstract: Antioxidant and Radical Scavenging Activities of Ascorbic Acid Derivatives Conjugated with Organogermanium. Cheminform, 42, 3513-3514. https://doi.org/10.1002/chin.201116213
|
[49]
|
Liu, G.Y. and Zhang, D.S. (1997) Effects of Ge-132 on Antioxidant Function of Dairy Cattle. Journal of Gansu Agricultural University, 32, 365-369.
|
[50]
|
Wang, J.C., Xing, G.S., Hu, W.D., Zhu, T.L., Wang, Q. and Zhao, H. (1994) Effects of Ge-132 on Oxygen Free Radicals and the Lipid Peroxidation Induced by Hydroxyl Free Radical in Vitro. Chinese Pharmaceutical Journal, 29, 24-25.
|
[51]
|
Yang, M.K. and Kim, Y.G. (1999) Protective Role of Germanium-132 against Paraquat-Induced Oxidative Stress in the Livers of Senescence-Accelerated Mice. Journal of Toxicology and Environmental Health Part A, 58, 289-297. https://doi.org/10.1080/009841099157250
|
[52]
|
Tang, Z.X. and Shi, Y. (1995) Effects of Ge-132 on Free Radical Metabolism of Parent-Filial Generation in the Laying Hens. I. Effects of Ge-l32 on Free Radical Metabolism of Blood and Some Tissues in Laying Hens. Chinese Journal of Veterinary Science, 15, 81-84.
|
[53]
|
Tang, Z.X. and Shi, Y. (1995b) Effects of Ge-132 on Free Radical Metabolism of Parent-Filial Generation in the Laying Hens II. Vertical Effects of Germanium on Free Radical Metabolism of Blood and Some Tissues of Filial Generation in Laying Hens. Chinese Journal of Veterinary Science, 15, 157-161.
|
[54]
|
Zhang, P.J. and Yu, Y. (1991) Pharmacological Effects of Ge-132. World Pharmacy, 12, 25-26.
|
[55]
|
Nakamura, T., Nagura, T., Akiba, M., Sato, K., Tokuji, Y., Ohnishi, M. and Osada, K. (2010) Promotive Effects of the Dietary Organic Germanium Poly-Trans-[(2-Carboxyethyl) Germasesquioxane] (Ge-132) on the Secretion and Antioxidative Activity of Bile in Rodents. Journal of Health Science, 56, 72-80. https://doi.org/10.1248/jhs.56.72
|
[56]
|
Pronai, L. and Arimori, S. (1992) Decreased Plasma Superoxide Scavenging Activity in Immunological Disorders-Carboxyethylgermanium Sesquioxide (Ge-132) as a Promoter of Prednisolone. Biotherapy, 4, 1-8. https://doi.org/10.1007/BF02171703
|
[57]
|
Harisch, G., Eikemeyer, J. and Schole, J. (1978) The Glutathione Status of the Rat Liver. Cellular and Molecular Life Sciences, 35, 719-720. https://doi.org/10.1007/BF01968201
|
[58]
|
Xiong, Z.Y. and Yang, H. (2008) Biological Function of Trace Element Germanium and Movement Ability. Journal of Qinghai Normal University (Natural Science), 4, 85-87.
|
[59]
|
Yuan, Y., Wen, P., Guo, D.X. and Tian, H. (2000) Effects of Organic and Inorganic Germanium on Lipid Metabolism of Broilers. Journal of Shenyang Agricultural University, 31, 203-206.
|
[60]
|
Tang, Z.X., Shi, Y., Zhao, J.Y., Ma, J., Sun, B.L. and Duan, W.F. (1995) Evaluation of Ge-132 on Laying Hen Performance. Heilongjiang Animal Husbandry and Veterinary Journal, 2, 13-15.
|
[61]
|
Tang, Z.X., Shi, Y. and Wang, Z.L. (1995) Effects of Ge-132 on Lipid Metabolism of Laying Hens. Heilongjiang Animal Husbandry and Veterinary Journal, 3, 1-5.
|
[62]
|
Qu, J. (2006) The Biological Functions of Germanium and Its Application in the Poultry Industry. Feed China, 9, 20-26.
|
[63]
|
Via, S. (1963) The Role of Trace Elements in Hematopoiesis. Terapevticheskii Arkhiv, 35, 3-14.
|
[64]
|
Sanai, T., Okuda, S., Onoyama, K., Oochi, N., Oh, Y., Kobayashi, K., Shimamatsu, K., Fujimi, S. and Fujishima, M. (1990) Germanium Dioxide. Nephron, 54, 53-60. https://doi.org/10.1159/000185810
|
[65]
|
Bodansky, M. (1923) The Effect of Germanium Dioxide on Red Cell Regeneration in Experimental Anemia. Experimental Biology & Medicine, 20, 534-535. https://doi.org/10.3181/00379727-20-266
|
[66]
|
Kong, T., Qu, Y.S. and Zhu, L.Q. (2007) Biological Function of Trace Element-Germanium. Studies of Trace Elements and Health, 24, 59-60.
|
[67]
|
Zhang, Y., Cheng, B.Y., Zuo, Y.S., Mao, S.Z., Zhang, J.H., Dai, S.W., Wang, J.R. and Yu, H.W. (1989) Effects of an Organic Germanium Compound (Ge-132) on Hematopoiesis. Journal of First Military Medical University, 9, 207-210.
|
[68]
|
Schwartz, G.N., Biegel, J.A., Fisher, B. and Klein, I. (1983) Spirogermanium: Effects on Hematopoietic Stem Cells and Survival of Normal and Tumor-Bearing Mice. Experimental Biology and Medicine, 173, 176-180. https://doi.org/10.3181/00379727-173-41627
|
[69]
|
Xu, C.S., Bi, S.W. and Zhang, X.F. (1996) Trace Elements-Germanium and Human Health. Studies of Trace Elements and Health, 2, 62-63.
|
[70]
|
Aso, H., Suzuki, F., Yamaguchi, T., Hayashi, Y., Ebina, T. and Ishida, N. (1982) Induction of Interferon and Activation of Nk Cells and Macrophages in Mice by Oral Administration of Ge-132, an Organic Germanium Compound. Gan to Kagaku Ryoho Cancer & Chemotherapy, 9, 1976-1980.
|
[71]
|
Arimori, S., Watanabe, K., Yoshida, M. and Nagano, T. (1981) Effect of Ge-132 on L1210. Immunomodulation by Microbiol. In: Yamamura, Y., et al., Eds., Products and Related Synthetic Compounds, Elsevier Science Publishing, Amsterdam, 536-539.
|
[72]
|
Park, S.K., Lee, S.W. and Kasumi, T. (1999) Effect of Germanium-132 on the Growth of Lactic Acid Bacteria. Korean Journal of Food Preservation, 6, 506-513.
|
[73]
|
Mrema, J.E.K., Slavik, M. and Davis, J. (1983) Spirogermanium: A New Drug with Antimalavial Activity against Clorooquine-Resistant Plasmodium Flaciparum. International Journal of Clinical Pharmacology, Therapy & Toxicology, 21, 167-171.
|
[74]
|
Feng, X.F. and Jin, W.G. (2006) Advance in Synthesis and Physiological Effect of Germanium Compounds. Food Science and Technology, 31, 177-181.
|
[75]
|
Slawson, R.M., Van, D.M.I., Lee, H. and Trevors, J.T. (1992) Germanium and Silver Resistance, Accumulation, and Toxicity in Microorganisms. Plasmid, 27, 72. https://doi.org/10.1016/0147-619X(92)90008-X
|
[76]
|
Dyke, M.I.V., Lee, H. and Trevors, J.T. (1989) Germanium Toxicity in Selected Bacterial and Yeast Strains. Journal of Industrial Microbiology & Biotechnology, 4, 299-306. https://doi.org/10.1007/BF01577353
|
[77]
|
Kaars, S.A. (1968) Growth Inhibition of Bacteria by Tributylgermanium Acetate and Its Reversal by Blood Constituents. Antonie van Leeuwenhoek, 34, 85-92. https://doi.org/10.1007/BF02046418
|
[78]
|
Wen, P., Ji, S.X. and Liu, S.J. (2010) The Effect of Inorganic Germanium on the Lipid Metabolism of Commodity Laying Hens. Heilongjiang Animal Husbandry and Veterinary Journal, 1, 67-68.
|
[79]
|
Li, J.F. (1993) Growth Promoting Effect and Toxicity of Germanium in Chickens. Archiv für Geflügelkunde, 57, 705-210.
|
[80]
|
Niu, Z.Y., Jiao, W.M., Liang, X. and Liu, F.Z. (2009) Effects of Carboxyethyl Germanium Sesquioxide (Ge-132) on Growth Performance and Immune Response of Broilers. Journal of the Chinese Cereals and Oils Association, 24, 98-101.
|
[81]
|
Ha, J.K. (1978) Effects of the Germanium Supplementation (as Germanium Dioxide) on the Performance of Chicken. Journal of the Institute for Agricultural Resource Utilization Gyeongsang University (Korea Republic), 12, 15-18.
|
[82]
|
Wen, P., Zhao, X.Y., Ao, Y., Qi, G.M. and Liu, Z.Y. (2000) The Effect of Two Types of Germanium Compound on the Production Performance of Meat Chicken. Feed Review, 4, 4-6.
|
[83]
|
Lee, W.B., Kim, I.H., Hong, J.W., Kwon, O.S., Min, B.J., Shon, K.S. and Jung, Y.K. (2004) Effect of Protein Level and Dietary Germanium Biotite on Egg Production, Egg Quality and Fecal Volatile Fatty Acid in Laying Hens. Korean Journal of Poultry Science, 30, 275-280.
|
[84]
|
Hong, J.W., Kwon, O.S., Min, B.J., Cho, J.H., Chen, Y.J., Shon, K.S., Kang, J.O. and Kim, I.H. (2006) Influences of Dietary Germanium Colloid on Growth Performance and Hematological Changes in Nursery Pigs. Journal of the Korean Society of International Agriculture, 16, 289-293.
|
[85]
|
Lee, W.B., Kim, I.H., Hong, J.W., Kwon, O.S. and Min, B.J. (2003) Effects of Dietary Germanium Biotite on Growth Performance and Blood Characteristics in Broiler Chicks. Korean Journal of Poultry Science, 30, 67-72.
|
[86]
|
Mu, K.H. and Feng, J. (2003) The Study of the Effection of Ge-132 on Cultured Melanocytes. The Chinese Journal of Dermatovenereology, 17, 91-95.
|
[87]
|
Feng, X.F. (2005) Germanium and Disease Prevention. Studies of Trace Elements and Health, 22, 62-63.
|
[88]
|
Ramalho, J., Marques, C., Pereira, P. and Mota, M.C. (1996) Crystallin Composition of Human Cataractous Lens May Be Modulated by Protein Glycation. Graefe’s Archive for Clinical and Experimental Ophthalmology, 234, S232-S238. https://doi.org/10.1007/bf02343078
|
[89]
|
Lin, K. (1997) Pathophysiology of Cataracts Copper Ion and Peroxidation in Diabetica. Japanese Journal of Ophthalmology, 41, 130-137. https://doi.org/10.1016/S0021-5155(97)00030-0
|
[90]
|
Dong, B., Su, X.D., Chen, C.Z. and Wang, H.L. (1998) Analysis of Germanium, Cadmium and Nickel in the Lenses of Senile Cataract Patients. Ophthalmology in China, 7, 190-192.
|
[91]
|
Unakar, N.J., Johnson, M.J., Cherian M. and Abraham, E.C. (1995) Effect of Germanium-132 on Galactose Cataracts and Glycation in Rats. Experimental Eye Researchm, 61, 155-164. https://doi.org/10.1016/S0014-4835(05)80035-1
|
[92]
|
Gao, S.Y. (1990) Pharmacology Activity of Lysine Germanium Oxide. Studies of Trace Elements and Health, 3, 3-5.
|
[93]
|
Sanai, T., Okuda, S., Onoyama, K., Oochi, N., Takaichi, S., Mizuhira, V. and Fujishima, M. (1973) Chronic Tubulointerstitial Changes Induced by Germanium Dioxide in Comparison with Carboxyethylgermanium Sesquioxide. Kidney International, 40, 882-890. https://doi.org/10.1038/ki.1991.289
|
[94]
|
Matsumoto, H., Jiang, G.Z., Hashimoto, T., Kuboyama, N., Yamane, J., Nonaka, K. and Fujii, A. (2002) Effect of Organic Germanium Compound (Ge-132) on Experimental Osteoporosis in Rats: The Relationship between Transverse Strength and Bone Mineral Density (BMD) or Bone Mineral Content (BMC). Radiology, 1, 10-16.
|
[95]
|
Matsusaka, T., Fujii, M., Nakano, T., Terai, T., Kurata, A., Imaizumi, M. and Abe, H. (1988) Germanium-Induced Nephropathy: Report of Two Cases and Review of the Literature. Clinical Nephrology, 30, 341-345.
|
[96]
|
Komuro, T., Kakimoto, N., Katayama, T. and Hazato, T. (1986) Inhibitory Effects of Ge-132 (Carboxyethyl Germanium Sesquioxide) Derivatives on Enkephalin-De- grading Enzymes. Biotechnology and Applied Biochemistry, 8, 379-386.
|
[97]
|
Fujii, A., Kuboyama, N., Yamane, J., Nakao, S. and Furukawa, Y. (1993) Effect of Organic Germanium Compound (Ge-132) on Experimental Osteoporosis in Rats. General Pharmacology, 24, 1527-1532. https://doi.org/10.1016/0306-3623(93)90447-6
|
[98]
|
Han, C., Wu, G., Yin, Y. and Shen, M. (1992) Inhibition by Germanium Oxide of the Mutagenicity of Cadmium Chloride in Various Genotoxicity Assays. Food and Chemical Toxicology, 30, 521-524. https://doi.org/10.1016/0278-6915(92)90104-S
|
[99]
|
Venugopal, B. and Luckey, T.D. (1978) Metal Toxicity in Mammals. Chemical Toxicity of Metals and Metalloids. Plenum Press.
|
[100]
|
Schroedher, H.A. and Balassa, J.J. (1967) Arsenic, Germanium, Tin and Vanadium in Mice: Effects on Growth, Survival and Tissue Levels. Journal of Nutrition, 92, 245-252.
|
[101]
|
Hao, W., Xu, Y.Q. and Wang, W.X. (2004) The Present Status of Research on Cancer Cachexia Metabolism. China Cancer, 13, 240-242.
|
[102]
|
Okada, K., Okagawa, K., Kawakami, K., Kuroda, Y., Morizumi, K., Sato, H., Morita, H., Shimomura, S. and Saito, S. (1989) Renal Failure Caused by Long-Term Use of a Germanium Preparation as an Elixir. Clinical Nephrology, 31, 219-224.
|
[103]
|
Krapf, R., Schaffner, T. and Iten, P.X. (1992) Abuse of Germanium Associated with Fatal Lactic Acidosis. Nephron, 62, 351-356. https://doi.org/10.1159/000187072
|
[104]
|
Kim, K.M., Lim, C.S., Kim, S., Kim, S.H., Park, J.H., Ahn, C., Han, J.S. and Lee, J.S. (1998) Nephropathy and Neuropathy Induced by a Germanium-Containing Compound. Nephrology, Dialysis, Transplantation, 13, 3218-3219. https://doi.org/10.1093/ndt/13.12.3218
|
[105]
|
Dixon, C., Hagemeister, F., Legha, S. and Bodey, G. (1984) Pulmonary Toxicity Associated with Spirogermanium. Cancer Treatment Reports, 68, 907-908.
|
[106]
|
Legha, S.S., Ajani, J.A. and Bodey, G.P. (1983) Phase I Study of Spirogermanium Given Daily. Journal of Clinical Oncology Official Journal of the American Society of Clinical Oncology, 1, 331-336.
|
[107]
|
Li, J.F. (1994) The Growth Promotion Effect and Toxicity of Two Germanium Compounds for Broiler Chickens. Chinese Journal of Animal Nutrition, 6, 23-29.
|
[108]
|
Arts, J.H.E., Til, H.P., Kuper, C.F., Neve, R. and Swennen, B. (1994) Acute and Subacute Inhalation Toxicity of Germanium Dioxide in Rats. Food and Chemical Toxicology, 32, 1037-1046. https://doi.org/10.1016/0278-6915(94)90144-9
|
[109]
|
Du, R., Wang, X.J., Ruan, X., Liu, X.S., Qu, Y.Q. and Yang, L.H. (2008) Regulation of Germanium-Enriched Barley Seedling on Immune Function of Mice. Food Science, 29, 578-581.
|
[110]
|
Wang, Y.S. (2001) Advanced Research of Germanium Nutrition in Poultry. China Feed, 23, 27-28.
|
[111]
|
Niu, Z.Y., Liu, F.Z., Wan, Y.S., Liang, X. and Xie, M. (2001) Effects of Germanium on the Growth of Main Immune Organs in Broilers. Journal of Northwest A&F University (Natural Science Edition), 10, 41-43.
|
[112]
|
Tang, Z.X., Chen, Y., Shi, Y., Wang, W. and Zhou, J.P. (1996) Effects of Organogermanium on Development of Immune Organs in Chickens. Journal of Anhui Agricultural University, 23, 145-150.
|
[113]
|
Zhang, G.L., Lu, S. and Zhong, H.L. (1997) Experimental Study on the Effects of Organic Germanium (Ge-201) on Nonspecific Immunity of Mice. Guangdong Trace Elements Science, 4, 38-39.
|
[114]
|
Xue, W.L., He, D.D., Li, X.S., Hao, B.H., Zhang, Z.B. and Chen, C.T. (2000) Effect of Zinc, Selenium and Germanium on the Immunity of Mice. Journal of Xi’an Medical University, 21, 16-17.
|
[115]
|
Si, C.P., Dang, X.L., Yu, J., Yang, J. and Yi, M.Y. (1994) The Enhancement Effect of Organic Germanium (Ge-132) on Immune Function. Shanghai Journal of Immunology, 14, 14-15.
|
[116]
|
Dang, X.L., Si, C.P., Yu, J., Yang, J. and Yi, M.Y. (1992) A Study of the Immunoregulation Effect of Carboxyethyl Germanium Sesgioxide (Ge-132). Journal of Jining Medical University, 15, 27-29.
|
[117]
|
Gao, Y., Xiao, H.Y., Zhang, Z.B., Hao, B.H. and Xue, W.L. (2001) Effect of Zinc, Selenium and Germanium on the Immunity of Mice. Journal of Hygiene Research, 30, 252-253.
|
[118]
|
Jung, M., Shin, M.K., Cha, S.B., Shin, S.W., Yoo, A., Lee, W.J., Park, H.T., Park, J.H., Kim, B., Jung, Y.K. and Yoo, H.S. (2014) Supplementation of Dietary Germanium Biotite Enhances Induction of the Immune Responses by Foot-and-Mouth Disease Vaccine in Cattle. BMC Veterinary Research, 10, 1-10. https://doi.org/10.1186/s12917-014-0179-6
|
[119]
|
Piao, Y.R., Cui, Y.D., Meng, F.P., Li, Y.X., Jin, X.L. and Cui, F.D. (1993) The Effects of Germanium-132 on Humoral Immunological Function of Mice. Journal of Medical Science Yanbian University, 16, 93-94.
|
[120]
|
Li, W.Y., Cheng, L.P., Peng, W., Zhu, Y.F., Gao, H.B. and Wang, Y.F. (1991) Immunomodulation of Organic Germanium (Ge-401) on Antibody Production of Mouse B Lymphocyte. Shanghai Journal of Immunology, 11, 197-199.
|
[121]
|
Joo, S.S., Won, T.J., Yong, J.L., Min, J.K., Park, S.Y., Lee, S.H., Hwang, K.W. and Lee, Y. (2006) Effect of Geranti Bio-Ge Yeast, a Dried Yeast Containing Biogermanium, on the Production of Antibodies by B Cells. Immune Network, 6, 86-92. https://doi.org/10.4110/in.2006.6.2.86
|
[122]
|
Suzuki, F., Brutkiewicz, R.R. and Pollard, R.B. (1985) Importance of T-Cells and Macrophages in the Antitumor Activity of Carboxyethylgermanium Sesquioxide (Ge-132). Anticancer research, 5, 479-483.
|
[123]
|
Si, C.P., Sun, W.D. and Wang, M.H. (1992) Effect of Carboxyethyl Germanium Ses-quioxide (Ge-132) on Cellular Immune Function in the Aged. Journal of Jining Medical University, 15, 12-13.
|
[124]
|
Yu, J. and Si, C.P. (1992) The Effects of Oral Organic Germanium on the Immune Function of RBC. Journal of Jining Medical University, 15, 29-30.
|
[125]
|
MunakaLa, T., Agai, S., Kumano, K. and Tomita, Y. (1987) Induction of Interferon Production by Natural Killer Cells by Organogermanium Compound-Ge-132. Journal of Interferon Research, 7, 69-76. https://doi.org/10.1089/jir.1987.7.69
|
[126]
|
Zhang, G.H., Li, W.H., Yang, Q.X., Li, C.R. and Liu, B.Q. (2000) Study of Exogenous Interferons Induced by Ge-132 in Chicken. Heilongjiang Animal Husbandry and Veterinary Journal, 5, 1-4.
|
[127]
|
Suzuki, F., Brutkiewicz, R.R. and Pollard R.B. (1985) Ability of Sera from Mice Treated with Ge-132, an Organic Germanium Compound, to Inhibit Experimental Murine Ascites Tumours. British Journal of Cancer, 52, 757-763. https://doi.org/10.1038/bjc.1985.254
|
[128]
|
Ishiwata, Y., Hashimoto, N. and Suzuki, T. (1998) Protection against Concanavalin A-Induced Murine Liver Injury by the Organic Germanium Compound, Propagermanium. Scandinavian Journal of Immunology, 48, 605-614. https://doi.org/10.1046/j.1365-3083.1998.00434.x
|