Prof. Sang Ho Choi

Seoul National University, South Korea



1992  Ph.D., University of Iowa, College of Medicine, USA

1985  M.Sc., Korea Advanced Institute of Science and Technology, South Korea

1982  B.A., Seoul National University, South Korea

Publications (Selected)

  1. Kim, BS, JW Hwang, MH Kim, and SH Choi. 2011. Cooperative Regulation of the Vibrio vulnificus nan Cluster by NanR, cAMP Receptor Protein, and N-Acetylmannosamine-6-Phosphate. J. Biol. Chem. In press.
  2. Lim MS, JA Kim, JK Lim, BS Kim, KH Lee, KC Jeong, and SH Choi. 2011. Identification and Characterization of a Novel Serine Protease, VvpS, That Contains Two Functional Domains and Is Essential for Autolysis of Vibrio vulnificus. J. Bacteriol. 193:3722-3732.
  3. Park JH, YJ Cho, J. Chun, YJ Seok, JK Lee, KS Kim, KH Lee, SJ Park, and SH Choi. 2011. Complete genome sequence of Vibrio vulnificus M06-24/O. J. Bacteriol. 193:2062-2063.
  4. Kim, Y., B.S. Kim, Y.J. Park, W.C. Choi, J. Hwang, B.S. Kang, T.K. Oh, S.H. Choi, and M.H. Kim. 2010. The crystal structure of SmcR, a quorum-sensing master regulator of Vibrio vulnificus, provides insight into its regulation of transcription. J. Biol. Chem. 285:14020-14030. [Co-corresponding author]
  5. Lee, B.C., M.S. Kim, S.H. Choi, and T.S. Kim, 2010. Involvement of capsular polysaccharide via a TLR2/NF-kappaB pathway in Vibrio vulnificus-induced IL-8 secretion of human intestinal epithelial cells. Int. J. Mol. Med. 25(4):581-91.
  6. Lee, B.C., M.S. Kim, D. Cho, S.H. Choi, and T.S. Kim, 2010. Co-culture supernatants from Vibrio vulnificus-infected INT-407 cells induce IL-8 production in intestinal epithelial cells: crucial role of V. vulnificus rtxE. Int. J. Mol. Med. 26:651-59.
  7. Jeong, H.S., S.M. Kim, M.S Lim, K.S. Kim, and S.H. Choi. 2010 Direct Interaction between Quorum Sensing Regulator SmcR and RNAP Is Mediated by IHF to Activate vvpE Encoding Elastase in Vibrio vulnificus. J. Biol. Chem. 285:9357-9366.
  8. Kho, M.J., H.S. Lee, J.E. Rhee, and S.H. Choi. 2010. Evidence That Vibrio vulnificus AhpC2 Is Essential for Survival Under High Salinity by Modulating Intracellular Level of ROS. J Microbiol. 48(1):129-133.
  9. Baek, W.K., H.S. Lee, M.H.Oh, M.J.Koh, K.S.Kim and S.H.Choi. 2009. Identification of the Vibrio vulnificus ahpC1 Gene and Its Influence on Survival under Oxidative Stress and Virulence. J. Microbiol. 47(5): 624-632.
  10. Lee, B.C., M.S. Kim, S.H. Choi, K.Y. Kim, and T.S. Kim. 2009. In vitro and in vivo antimicrobial activity of water-soluble chitosan oligosaccharides against Vibrio vulnificus. Int J Mol Med. 24(3): 327-333.
  11. Li, H.Shinde, P.B., H.J. Lee, E.S. Yoo, C.O. Lee, J. Hong, S.H. Choi, and J.H. Jung. 2009. Bile acid derivatives from a sponge-associated bacterium Psychrobacter sp. Arch Pharm Res. 32(6): 857-862.
  12. Jeong, H.G., M.H. Oh, B.S. Kim, M.Y. Lee, H.J. Han, and S.H. Choi. 2009. The capability of catabolic utilization of N-Acetylneuraminic acid, a salic acid, is essential for vibrio vulnificus pathogenesis. Infect. Immun. 77: 3209-3217.
  13. Oh,M.H., S. M. Lee, D. H. Lee, and S. H. Choi.2009.Regulation of the Vibrio vulnificus hupA Gene by Temperature Alteration and Cyclic AMP Receptor Protein and Evaluation of Its Role in Virulence. Infect. Immun. 77:1208-1215.
  14. Rhee, J. E., K. S. Kim, and S. H. Choi. 2008. Activation of the Vibrio vulnificus cadBA operon by Leucine-Responsive regulatory protein is mediated by CadC. J. Microbiol. Biotechnol. 18(11): 1755-1761.
  15. Lee, D. H., H. S. Jeong, H. G. Jeong, K. M. Kim, H. Kim, and S. H. Choi. 2008 A consensus sequence for binding of SmcR, a Vibrio vulnificus LuxR homologue and genomewide indentification of the SmcR regulon. J. Biol. Chem. 283(35): 23610-23618.
  16. Lee, H. J., S. J. Park, S. H. Choi, and K. H. Lee. 2008 Vibrio vulnificus rpoS expressed by direct binding of cAMP-cAMP receptor protein complex to its two promoter regions. J. Biol. Chem. 283(45): 30438-30450.
  17. Lee, B. C., S. H. Choi, and T.S. Kim. 2008 Vibrio vulnificus RTX toxin plays an important role in the apoptotic death of human intestinal epithelial cells exposed to Vibrio vulnificus . Microbes Infect. 10:1504-1513.
  18. Huayue Li., B. C. Lee, T. S. Kim, K. S. Bae, J. K. Hong, S. H. Choi, B. Bao, and J. H. Jung. 2008 Bioactive cyclic dipeptides from a marine sponge-associated bacterium, Phychrobacter sp. Biomol. Ther. 16: 356-363.