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Biography
Dr. Lu Yong

Cleveland Clinic Lerner Research Institute, USA


Email: Luy2@ccf.org


Qualifications

2009 Ph.D., China Pharmaceutical University, Biochemistry and Molecular Biology

2004 B.Sc., China Pharmaceutical University, Biology


Publications (Selected)

  1. Lu Yong, Jing Yang, and Qing Yi. "Signaling of Tumor-Induced Immunosuppression of Dendritic Cells." The Tumor Immunoenvironment, pp. 339-360. Springer Netherlands, (2013).
  2. Lu Yong, Sungyoul Hong, Haiyan Li, Jungsun Park, Bangxing Hong, Lijuan Wang, Yuhuan Zheng et al. "Th9 cells promote antitumor immune responses in vivo." The Journal of clinical investigation 122, no. 11 (2012): 4160.
  3. Lu Yong, and Qing Yi. "Utilizing TH9 cells as a novel therapeutic strategy for malignancies." OncoImmunology 2, no. 3 (2013): 0-1.
  4. Yong Lu, Zhang Huiyong, Hou Jing, Wang Huaqian, Hu Xiangbing, Ma Yanjun, Ge Xiaoyu et al. "Vaccination with a potent DNA vaccine targeting B-cell epitopes of hGRP induces prophylactic and therapeutic antitumor activity in vivo." Gene therapy 17, no. 4 (2010): 459-468.
  5. Yong Lu, Sun Yunxiao, Xiong Qiyan, Zhang Yu, Hou Jing, Didier JL Mekoo, Zhang Fan et al. "Immunization with P277 induces vascular leak syndrome in C57BL/6 mice via endothelial damage." Autoimmunity 43, no. 8 (2010): 654-663.
  6. Lu Yong, Kedong Ouyang, Jing Fang, Huiyong Zhang, Guojun Wu, Yanjun Ma, Yu Zhang et al. "Improved efficacy of DNA vaccination against prostate carcinoma by boosting with recombinant protein vaccine and by introduction of a novel adjuvant epitope." Vaccine 27, no. 39 (2009): 5411-5418.
  7. Yong Lu, Zhang Huiyong, Fang Jing, Wang Huaqian, You Kejun, Yang Yanan, Liu Suli et al. "Study on preparation and unique properties of a novel insulin analogue with N-terminal Arg-4, Pro-3, Lys-2, Pro-1extension at insulin B-chain." Regulatory peptides 157, no. 1 (2009): 92-98.
  8. Lu Yong, Didier JL Mekoo, Kedong Ouyang, Xiangbing Hu, Yanhua Liu, Ming Lin, Liang Jin et al. "Strong humoral response elicited by a DNA vaccine targeting gastrin-releasing peptide with optimized adjuvants inhibits murine prostate carcinoma growth in vivo." Endocrine-related cancer 16, no. 4 (2009): 1171-1184.
  9. Lu Yong, Hua-qian WANG, Ke-dong OUYANG, Hui-yong ZHANG, Xiang-bing HU, Tai-ming LI, Rong-yue CAO, and Jing-jing LIU. "A DNA Vaccine Targeting Gastrin-Releasing Peptide with High Immunogenicity and Its Inhibitory Action on the Growth of Prostate Carcinoma in vivo." Pharmaceutical Biotechnology 5 (2009).
  10. Huiyong, Zhang, Lu Yong, Mekoo Didier, Zhang Yu, Fang Jing, Cao Rongyue, and Liu Jingjing. "Enhanced inhibition of murine prostatic carcinoma growth by immunization with or administration of viable human umbilical vein endothelial cells and CRM197." Brazilian Journal of Medical and Biological Research 44, no. 2 (2011): 140-148.
  11. Lin Ming, Yong Lu, Yu Zhang, Yan-fei XIE, Xiang-bing HU, Hua-qian WANG, Tai-ming LI, Jie WU, Jing-jing LIU, and Rong-yue CAO. "Study on HSP65 DNA vaccine in the hamatogenous metastasis of B16/F10 melanoma." Pharmaceutical Biotechnology 16, no. 2 (2009): 118-122.
  12. YOU, Ke-jun, Yong LU, Ming LIN, Jing KONG, Rong-yue CAO, Jing-jing LIU, Hao FAN, and Li ZONG. "Preparation and Pharmacodynamics Study of a Novel Rapid-Acting Analog of Human Insulin [J]." Pharmaceutical Biotechnology 4 (2009): 2010.
  13. Ma, Yan-Jun, Yong Lu, Jing Hou, Yuan-Kai Dong, Ming-Zhu Du, Yun Xing, Chi-Yu Ge et al. "Vaccination of non-obese diabetic mice with a fragment of peptide P277 attenuates insulin-dependent diabetes mellitus." International immunopharmacology 11, no. 9 (2011): 1298-1302.
  14. ZHANG Hui-yong, Yong LU, Yu-han MENG, Rong-yue CAO, Jing-jing LIU, and Tai-ming LI. "The Preliminary Study on VEGF 183 (132-158) as One Kind of Protein Drug Carrier Binding with the Extracellular Matrix." Pharmaceutical Biotechnology 17, no. 3 (2010): 198-202.
  15. LIU Su-li, Yong LU, Xue-jun WANG, Rong-yue CAO, Jing-jing LIU, Hao FAN, and Tai-ming LI. "Construction, preparation and properties of a novel short-acting human insulin analog." Journal of Southeast University (Medical Science Edition) 5 (2009): 2002.
  16. Jing, Hou, Lu Yong, Liu Haiyan, Ma Yanjun, Xing Yun, Zhang Yu, Li Taiming et al. "Oral administration of Lactococcus lactis delivered heat shock protein 65 attenuates atherosclerosis in low-density lipoprotein receptor-deficient mice." Vaccine 29, no. 24 (2011): 4102-4109.
  17. Huiyong, Zhang, Lu Yong, Sun Yunxiao, Zhu Wuling, Liu Jingjing, and Li Taiming. "Generation of a Chimeric Plasmin-resistant VEGF165/VEGF183 (132-158) Protein and its Comparative Activity." Protein and peptide letters 20, no. 8 (2013): 947-954. Yunxiao Sun, Yong Lu, Zhufang Li and Qiang Xu et al, "Immunology Effects of Anti-atherosclerosis Protein Vaccines Based on Heat Shock Protein 65." Chinese journal of biotechnology 31, no. 1 (2011): 12-18.
  18. Zhu, A., Y. Lu, L. Jin, J. Wu, T. Li, and J. Liu. "Improved efficacy of P277 fused to heat shock protein 65 of Mycobacterium tuberculosis against diabetes in nonobese diabetic mice." Chinese journal of biotechnology 24, no. 4 (2008): 640.
  19. Gu Juefen, Lu Yong, Progresses in development of tumor target therapy with immunoconjugates constructed by monoclonal antibody and antitumor antibiotics, Chinese Journal of Medical Biotechnology, 2006,12(4): 1-5. (Chinese Journal).
  20. Wang, Lijuan, Jianfei Qian, Yong Lu, Haiyan Li, Hanying Bao, Donghua He, Zhiqiang Liu et al. "Immune evasion evasion of mantle cell lymphoma: expression of B7-H1 leads to inhibited T-cell response to and killing of tumor cells." Haematologica (2013).