Prof. James Michael Mathis

Department of Cellular Biology and Anatomy

Feist-Weiller Cancer Center

LSU Health Sciences Center, USA




2011 M.H.A., Health Admin, Louisiana State University in Shreveport

1987 Ph.D., Univ. of Texas Southwestern Medical Center, Biochemistry

1982 B.S., Texas A M University, Chemistry

Publications (Selected)

  1. Li XL, Zhang DQ, Wang D, Knight DS, Yin L, Bao J, Liu YY, Glass J, Mathis JM, Zhang QJ. In vivo survivors of transformed mouse ovarian surface epithelial cells display diverse phenotypes for gene expression and tumorigenicity. Tumour Biol. 2008; 29(6): 359-70. Epub 2008 Dec 3. PubMed PMID: 19052485.
  2. Sonabend AM, Ulasov IV, Tyler MA, Rivera AA, Mathis JM, Lesniak MS. Mesenchymal stem cells effectively deliver an oncolytic adenovirus to intracranial glioma. Stem Cells. 2008 Mar; 26(3): 831-41. Epub 2008 Jan 10. PubMed PMID: 18192232.
  3. Stoff-Khalili MA, Rivera AA, Nedeljkovic-Kurepa A, DeBenedetti A, Li XL, Odaka Y, Podduturi J, Sibley DA, Siegal GP, Stoff A, Young S, Zhu ZB, Curiel DT, Mathis JM. Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control. Breast Cancer Res Treat. 2008 Mar;108(1): 43-55. Epub 2007 May 17. PubMed PMID: 17508279; PubMed Central PMCID: PMC2268614.
  4. Siegele B, Cefalu C, Holm N, Sun G, Tubbs J, Meschonat C, Odaka Y, DeBenedetti A, Ghali GE, Chu Q, Mathis JM, Li BD. eIF4E-targeted suicide gene therapy in a minimal residual mouse model for metastatic soft-tissue head and neck squamous cell carcinoma improves disease-free survival. J Surg Res. 2008 Jul; 148(1): 83-9. Epub 2008 Apr 9. PubMed PMID: 18570935.
  5. Zhang QJ, Li XL, Wang D, Huang XC, Mathis JM, Duan WM, Knight D, Shi R, Glass J, Zhang DQ, Eisenbach L, Jefferies WA. Trogocytosis of MHC-I/peptide complexes derived from tumors and infected cells enhances dendritic cell cross-priming and promotes adaptive T cell responses. PLoS One. 2008 Aug 29; 3(8): e3097. PubMed PMID: 18769733; PubMed Central PMCID: PMC2518214.
  6. Kleiner HE, Krishnan P, Tubbs J, Smith M, Meschonat C, Shi R, Lowery-Nordberg M, Adegboyega P, Unger M, Cardelli J, Chu Q, Mathis JM, Clifford J, De Benedetti A, Li BD. Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer. J Exp Clin Cancer Res. 2009 Jan 9;28:5. Erratum in: J Exp Clin Cancer Res. 2009;28:54. PubMed PMID: 19134194; PubMed Central PMCID: PMC2631459.
  7. Stoff A, Rivera AA, Sanjib Banerjee N, Moore ST, Michael Numnum T, Espinosa-de-Los-Monteros A, Richter DF, Siegal GP, Chow LT, Feldman D, Vasconez LO, Mathis JM, Stoff-Khalili MA, Curiel DT. Promotion of incisional wound repair by human mesenchymal stem cell transplantation. Exp Dermatol. 2009 Apr;18(4): 362-9. Epub 2008 Sep 18. PubMed PMID: 18803656; PubMed Central PMCID: PMC2664391.
  8. Li XL, Liu YY, Knight D, Odaka Y, Mathis JM, Shi R, Glass J, Zhang QJ. Effect of B7.1 costimulation on T-cell based immunity against TAP-negative cancer can be facilitated by TAP1 expression. PLoS One. 2009 Jul 24;4(7):e6385. PubMed PMID: 19629186; PubMed Central PMCID: PMC2711302.
  9. Kleiner-Hancock HE, Shi R, Remeika A, Robbins D, Prince M, Gill JN, Syed Z, Adegboyega P, Mathis JM, Clifford JL. Effects of ATRA combined with citrus and ginger-derived compounds in human SCC xenografts. BMC Cancer. 2010 Jul 26; 10: 394. PubMed PMID: 20659317; PubMed Central PMCID: PMC2916922.
  10. Short JJ, Rivera AA, Wu H, Walter MR, Yamamoto M, Mathis JM, Curiel DT. Substitution of adenovirus serotype 3 hexon onto a serotype 5 oncolytic adenovirus reduces factor X binding, decreases liver tropism, and improves antitumor efficacy. Mol Cancer Ther. 2010 Sep; 9(9): 2536-44. Epub 2010 Aug 24. PubMed PMID: 20736345; PubMed Central PMCID: PMC2945233.
  11. Veluswamy H, Suryawala K, Sheth A, Wells S, Salvatierra E, Cromer W, Chaitanya GV, Painter A, Patel M, Manas K, Zwank E, Boktor M, Baig K, Datti B, Mathis MJ, Minagar A, Jordan PA, Alexander JS. African-American inflammatory bowel disease in a Southern U.S. health center. BMC Gastroenterol. 2010 Sep 9; 10: 104. PubMed PMID: 20828408; PubMed Central PMCID: PMC2944337.
  12. Cromer W, Jennings MH, Odaka Y, Mathis JM, Alexander JS. Murine rVEGF164b, an inhibitory VEGF reduces VEGF-A-dependent endothelial proliferation and barrier dysfunction. Microcirculation. 2010 Oct; 17(7): 536-47. doi: 10.1111/j.1549-8719.2010.00047.x. Erratum in: Microcirculation. 2010 Nov; 17(8): 669. PubMed PMID: 21040119; PubMed Central PMCID: PMC3057765.
  13. Becks L, Prince M, Burson H, Christophe C, Broadway M, Itoh K, Yamamoto M, Mathis M, Orchard E, Shi R, McLarty J, Pruitt K, Zhang S, Kleiner-Hancock HE. Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene. BMC Cancer. 2010 Oct 8; 10: 540. PubMed PMID: 20932318; PubMed Central PMCID: PMC2964634.
  14. Davis JN, Rogers D, Adams L, Yong T, Jung JS, Cheng B, Fennell K, Borazanci E, Moustafa YW, Sun A, Shi R, Glass J, Mathis JM, Williams BJ, Meyers S. Association of core-binding factor β with the malignant phenotype of prostate and ovarian cancer cells. J Cell Physiol. 2010 Nov; 225(3): 875-87. PubMed PMID: 20607802.
  15. Chaitanya GV, Franks SE, Cromer W, Wells SR, Bienkowska M, Jennings MH, Ruddell A, Ando T, Wang Y, Gu Y, Sapp M, Mathis JM, Jordan PA, Minagar A, Alexander JS. Differential cytokine responses in human and mouse lymphatic endothelial cells to cytokines in vitro. Lymphat Res Biol. 2010 Sep; 8(3): 155-64. PubMed PMID: 20863268.

Last Updated: August, 2012