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Biography

Prof. David T. Harris

University of Arizona, USA

Professor of Immunology


Email: davidh@email.arizona.edu


Qualifications

1980-1982   Ph.D., Wake Forest University, USA

1978-1979   M.S., Wake Forest University, USA

1974-1978   B.S., Wake Forest University, USA


Publications(Selected)


Books

  1. Hale, A.H., M.J. Ruebush and D.T. Harris. Study of the minimal molecular and cellular requirements for elicitation of anti-vesicular stomatitus virus specific cytotoxic T lymphocytes using purified viral and cellular antigens incorporated into phospholipid vesicles. In: Liposomes and Immunobiology, Tom/Six(Eds.), Elsevier/North Holland, Inc., p.211, 1980.
  2. Harris, D.T., L. Friedmann, R.B. Devlin, H.S. Koren and D.L. Evans. Analysis of a human natural killer cell antigen receptor. Proceedings of the 5th International NK Workshop (1988), In: Natural Killer Cells and Host Defense, Editors: E.W. Ades and C. Lopez, Karger Press, Basel, Switzerland, p. 172-176, 1989.
  3. Harris, D.T., L. Jaso-Friedmann, R.D. Devlin, K.P. McKinnon, H.S. Koren and D.L. Evans. Identification of an evolutionarily conserved natural killer cell (NK) antigen receptor/target antigen complex. In: Defense Molecules, UCLA Symposia on Molecular and Cellular Biology, New Series, Vol. 121, Editors: J. Marchalonis and C. Reinisch, Alan R. Liss, Inc., New York, NY, 213-227, 1990.
  4. Harris, D.T., L. Friedmann, R.B. Devlin, K.P. McKinnon, H.S. Koren and D.L. Evans.  A putative antigen receptor on human natural killer cells is a signal-transducing molecule. In: Natural Killer Cells: Biology and clincial application (Preceedings of the 6th International Natural Killer Workshop), R.E. Schmidt, Ed., Karger Press, Basel, Switzerland, p.10-12, 1990.
  5. Evans, D.L., D.T. Harris, H.S. Koren and L. Friedmann.  Identification of a recognition structure on rat natural killer cells. In:Natural Killer Cells: Biology and clinical application (Preceedings of the 6th International Natural Killer Workshop), R.E. Schmidt, Ed., Karger Press, Basel, Switzerland, p.5-9, 1990.
  6. Friedmann, L., D.T. Harris, A. St. John, H.S. Koren and D. L. Evans. Characterization of an evolutionary conserved target cell antigen complex recognized by natural killer cells. In: Natural Killer Cells: Biology and clinical application (Preceedings of the 6th International Natural Killer Workshop), R.E. Schmidt, Ed., Karger Press, Basel, Switzerland, p.13-17, 1990.
  7. Harris, D.T., L. Friedmann and D.L. Evans.  1992. Modulation of function-associated molecules on NK cells alters recognition and cytotoxicity. In: NK Cell Mediated Cytotoxicity: Receptors, Signaling and Mechanisms.  Eds. Lotzova and Herberman. CRC Press, p. 53-65, 1992.
  8. Harris, D.T. The effects of aerosolized JP-8 jet fuel exposure on the immune system: A review. In: JP-8 Jet Fuel, M. Witten, E. Zeiger, and GD Ritchie, Eds., Taylor & Francis, New York, NY; pp. 181-199, 2010.
  9. Harris, D.T.  Non-haematological uses of cord blood stem cells.  In: Therapeutic potential of umbilical cord blood cells for the treatment of nonhematological diseases.  Eds. MA Paltsev & VN Smirnov, Moscow, 2011.

Journals

  1. Cohen-Barak, O, DT Erickson, MS Badowski, DA Fuchs, CL Klassen, DT Harris & MH Brilliant. Stem cell transplantation demonstrates Sox6 epsilon/gamma-globin expression in definitive erythropoiesis of adult mice, Exp. Hematology 35(3): 358-367, 2007.
  2. Luo, P, TC Tsang, B Reed, RA Flavell and DT Harris. A self-augmenting gene expression cassette for enhanced and sustained transgene expression in the presence of inflammatory cytokines. DNA and Cell Biology 25(12): 659-667, 2006.
  3. Young, BK, JE Baumgartner, N Chen, C. Cox, M Haller, JM Hare, DT Harris, CP McGuckin, A Nagler and RH Schwarz. Emerging Stem Cell Therapies: The Role of Cord Blood Banks. OBG Management 18 (Suppl 1): S1-16, 2006.
  4. Young, BK, JE Baumgartner, N Chen, C. Cox, M Haller, JM Hare, DT Harris, CP McGuckin, A Nagler and RH Schwarz. Emerging Stem Cell Therapies: The Role of Cord Blood Banks. The Journal of Family Practice, 55 (10): S1-16, 2006.
  5. Harris DT, He X, Badowski M, Nicols JC.  Regenerative Medicine of the Eye: A Short Review. Stem Cell Repair & Regeneration, Vol. 3, Levicar N, Habib NA, Dimarakis I, Gordon MY (Ed.s). Imperial College Press, p. 211-225, London, 2008.
  6. Harris, David T, Michael Badowski, Nafees Ahmad, and Mohamed Gaballa.  The Potential of Cord Blood Stem Cells for Use in Regenerative Medicine. Expert Opinion on Biological Therapy (2008) 7(9): 1311-1322.
  7. Harris, DT and I Rogers.  Umbilical cord blood: a unique source of pluripotent stem cells for regenerative medicine. Current Stem Cell Research & Therapy, 2: 301-309, 2007.
  8. Harris, DT, D. Sakiestewa, D. Titone and M Witten.  JP-8 jet fuel exposure induces high levels of IL-10 and PGE2 secretion and is correlated with loss of immune function. Tox. Indus. Health 23: 223-230, 2007.
  9. Harris, DT, D Sakiestewa, X He, D Titone and M Witten.  Effects of in utero JP-8 jet fuel exposure on the immune systems of pregnant and newborn mice. Tox. Indus. Health, 23: 545-552, 2008.
  10. Harris, David T., Debbie Sakiestewa, Dominic Titone, Xianghui He, Juanita Hyde and Mark Witten. JP-8 Jet Fuel Exposure Potentiates Tumor Development in Two Experimental Model Systems. Tox. Indus. Health, 23: 617-623, 2008.
  11. Harris, David T., Debbie Sakiestewa, Dominic Titone, Xianghui He, Juanita Hyde and Mark Witten. JP-8 Jet Fuel Exposure Suppresses the Immune Response to Viral Infections. Tox. Indus. Health 24(4): 209-216, 2008
  12. Harris, DT. Collection, Processing and Banking of Umbilical Cord Blood Stem Cells for Clinical Use in Transplantation and Regenerative Medicine. Lab Medicine 39(3): 8-13, 2008.
  13. Wellensiek, BP, Ramakrishnan, R., Sundaravaradan V, Mehta R, Harris DT, and Ahmad N. Differential HIV-1 Integration Targets More Actively Transcribed Host Genes in Neonatal than Adult Blood Mononuclear Cells.  Virology 385: 28-38, 2009.
  14. Man Lung Yeung, Jun-ichirou Yasunaga, Yamina Bennasser, Nelson Dusetti, David Harris, Nafees Ahmad, Masao Matsuoka and Kuan-Teh Jeang. Roles for microRNAs, miR-93 and miR-130b, and TP53INP1 tumor suppressor in cell growth dysregulation by HTLV-1. CANCER RESEARCH, 68 (21): 1-10, 2008.
  15. Willert, J., T. Purdon and DT Harris. Umbilical cord blood-biology, banking and therapeutic use. US OB-GYN 3 (1): 67-72, 2008.
  16. Copeland, N., D. Harris and MA Gaballa. Human umbilical cord blood stem cells, myocardial infarction and stroke. Clinical Medicine 9 (4): 342-345, 2009.
  17. Michael Badowski and David T. Harris. Increasing transduction efficiency by lentivirus vectors using heat shock and cell cycle specific integration. Gene Therapy and Molecular Biology, Vol 13: 284-293, 2009.
  18. Michael S Badowski, Tong Zhang, Tom C Tsang, David T Harris. Chimeric Antigen Receptors for Stem Cell Based Immunotherapy.  J Exp Therapeutics & Oncology, 8 (1): 53, 2009.
  19. Harris, D.T. Cord blood stem cells: worth the investment.  Nature Reviews Cancer 8: U23, 2008.
  20. Vasudha Sundaravaradan, Roshni Mehta, David Harris, Jerome A Zack, Nafees Ahmad. Differential Expression and Interaction of Host Factors Augment HIV-1 Gene Expression in Neonatal Mononuclear Cells.  Virology 400: 32-43, 2010.
  21. Badowski, MS and DT Harris.  Collection, Processing and Banking of umbilical cord blood stem cells for transplantation and regenerative medicine. In: Somatic Stem Cells: Methods and Protocols, Methods in Molecular Biology, SR Singh (Ed), Humana Press+Springer Science, 879: 279-290, 2012.
  22. Harris, DT, J Wang, X He, S Cho Brett, ME Moore and H Brown.  Studies on Practical Issues for Cord Blood Banking: Effects of Ionizing Radiation and Cryopreservation Variable. The Open Stem Cell Journal, Feb 2011 (ISSN: 1876-8938 - Volume 2, 2010). DOI: 10.2174/1876893801002010037; 2010, 2, 37-44.