Dr. Manuel Narváez Peláez

Department of Human Physiology and Sport Medicine, Faculty of Medicine

University of Málaga, Spain



2012 Ph.D., University of Malaga, Spain

2005 M.D., Medicine and Surgery, University of Malaga, Spain

Publications (Selected)

  1. Borroto-Escuela DO, Romero-Fernandez W, Garriga P, Ciruela F, Narvaez M, Tarakanov AO, Palkovits M, Agnati LF, Fuxe K. G protein-coupled receptor heterodimerization in the brain. Methods Enzymol. 2013;521:281-94.
  2. Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Calvo F, Garriga P, Tena M, Narvaez M, Millón C, Parrado C, Ciruela F, Agnati LF, Narvaez JA, Díaz-Cabiale Z. On the existence and function of galanin receptor heteromers in the central nervous system. Front Endocrinol (Lausanne). 2012;3:127
  3. Borroto-Escuela DO, Romero-Fernandez W, Pérez-Alea M, Narvaez M, Tarakanov AO, Mudó G, Agnati LF, Ciruela F, Belluardo N, Fuxe K. The existence of FGFR1-5-HT1A receptor heterocomplexes in midbrain 5-HT neurons of the rat: relevance for neuroplasticity. J Neurosci. 2012 May 2;32(18):6295-303.
  4. Borroto-Escuela DO, Romero-Fernandez W, Mudó G, Pérez-Alea M, Ciruela F, Tarakanov AO, Narvaez M, Di Liberto V, Agnati LF, Belluardo N, Fuxe K. Fibroblast growth factor receptor 1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity. Biol Psychiatry. 2012 Jan 1;71(1):84-91
  5. Romero-Fernandez W, Borroto-Escuela DO, Tarakanov AO, Mudó G, Narvaez M, Pérez-Alea M, Agnati LF, Ciruela F, Belluardo N, Fuxe K. Agonist-induced formation of FGFR1 homodimers and signaling differ among members of the FGF family. Biochem Biophys Res Commun. 2011 Jun 17;409(4):764-8
  6. Díaz-Cabiale Z, Parrado C, Narváez M, Puigcerver A, Millón C, Santín L, Fuxe K, Narváez JA. Galanin receptor/Neuropeptide Y receptor interactions in the dorsal raphe nucleus of the rat. Neuropharmacology. 2011 Jul-Aug;61(1-2):80-6
  7. Díaz-Cabiale Z, Parrado C, Narváez M, Millón C, Puigcerver A, Fuxe K, Narváez JA. Neurochemical modulation of central cardiovascular control: the integrative role of galanin. EXS. 2010;102:113-31
  8. Borroto-Escuela DO, Correia PA, Romero-Fernandez W, Narvaez M, Fuxe K, Ciruela F, Garriga P . Muscarinic receptor family interacting proteins: role in receptor function. J Neurosci Methods. 2011 Feb 15;195(2):161-9
  9. Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Gómez-Soler M, Corrales F, Marcellino D, Narvaez M, Frankowska M, Flajolet M, Heintz N, Agnati LF, Ciruela F, Fuxe K. Characterization of the A2AR-D2R interface: focus on the role of the C-terminal tail and the transmembrane helices. Biochem Biophys Res Commun. 2010 Nov 26;402(4):801-7.
  10. Díaz-Cabiale Z, Parrado C, Narváez M, Millón C, Puigcerver A, Fuxe K, Narváez JA. The Galanin N-terminal fragment (1-15) interacts with neuropeptide Y in central cardiovascular control: Involvement of the NPY Y2 receptor subtype. Regul Pept. 2010 Aug 9;163(1-3):130-6
  11. Borroto-Escuela DO, Correia PA, Perez Alea M, Narvaez M, Garriga P, Fuxe K, Ciruela F. Impaired M(3) muscarinic acetylcholine receptor signal transduction through blockade of binding of multiple proteins to its third intracellular loop. Cell Physiol Biochem. 2010;25(4-5):397-408
  12. Vela C, Diaz-Cabiale Z, Parrado C, Narvaez M, Covenas R, Narvaez JA. Involvement of oxytocin in the nucleus tractus solitarii on central cardiovascular control: interactions with glutamate. J Physiol Pharmacol. 2010 Feb;61(1):59-65.
  13. Borroto-Escuela DO, Marcellino D, Narvaez M, Flajolet M, Heintz N, Agnati L, Ciruela F, Fuxe K. A serine point mutation in the adenosine A2AR C-terminal tail reduces receptor heteromerization and allosteric modulation of the dopamine D2R. Biochem Biophys Res Commun. 2010 Mar 26;394(1):222-7
  14. Borroto-Escuela DO, Narvaez M, Marcellino D, Parrado C, Narvaez JA, Tarakanov AO, Agnati LF, Díaz-Cabiale Z, Fuxe K. Galanin receptor-1 modulates 5-hydroxtryptamine-1A signaling via heterodimerization. Biochem Biophys Res Commun. 2010 Mar 19;393(4):767-72.