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Biography
Prof. Andrei P. Surguchov

Prof. Andrei P. Surguchov

Kansas University Medical Center, USA


Email: asurguchov@kumc.edu


Qualifications


Ph.D., Molecular Biology, Cardiology Research Center, Russia

M.Sc., Molecular Biology, Moscow State University, Russia

B.Sc., Biochemistry, Moscow State University, Russia


Publications (selected)

  1. A.P. Surguchov, M.V. Telkov and V.N. Smirnov. 1986. Absence of structural homology between sup1 and sup2 genes of yeast S. cerevisiae and identification of their transcripts. FEBS Letters, 206,1, 147 - 150
  2. Kushnirov, V.V., Ter-Avanesyan, M.D., Surguchov, A.P., Smirnov, V.N., Inge-Vechtomov, S.G. 1987. Localization of possible functional domains in sup2 gene product of the yeast S. cerevisiae. FEBS Letters, 215, 2, pp.257 - 260
  3. Kushnirov V.V., Ter-Avanesyan, M.D.,Surguchov A.P., V.N. Smirnov, S.G. Inge-Vechtomov. 1988. Nucleotide sequence of the sup2 gene of yeast S. cerevisiae. Gene, 66, pp. 45 - 54
  4. V.A. Kosykh, A.P. Surguchov, E.E. Podrez, V.N. Smirnov. 1988. 7-ketocholesterol inhibits VLDL secretion by cultured human and rabbit hepatocytes. Biochim Biophys Res Comm 153, 3, pp. 1116 - 1122
  5. V.A. Kosykh, E.A. Podrez, A.B. Novikov, A.P.Surguchov, V.N. Smirnov.1988. VLDL apoprotein secretion and apoB mRNA level in primary cultures of cholesterol loaded rabbit hepatocytes. FEBS Letters, v. 232, 1, pp. 103 - 106
  6. A.P. Surguchov. 1987. Common genes for mitochondrial and cytoplasmic proteins. Trends in Biochemical Sciences (TIBS). v. 12, 9, pp. 335 - 339
  7. A.P. Surguchov. 1988. Omnipotent nonsense suppressors : new clues to an old puzzle. Trends in Biochemical Sciences (TIBS), v. 13, 4, pp. 120 - 123
  8. A.B. Sudarikov and A.P. Surguchov. 1988. Probe for rabbit apolipoprotein B gene. Nucleic Acids Research, v.16, 16, p. 8187
  9. A.P. Surguchov. 1990. Apolipoprotein gene family : organization of upstream elements and regulation of gene expression. Biomedical Sciences, Turpin Transactions Ltd., Pion Ltd., v. 1, No. 4, pp. 344 - 354
  10. A.P. Surguchov . 1991. Migration of promoter elements between genes : a role in transcriptional regulation and evolution. Biomedical Sciences (Turpin Transactions Ltd., Pion Ltd.) , v. 2, pp. 22 - 28
  11. A.P. Surguchov, E. Boerwinkle, R. Sharett, W. Patsch. 1994. Apolipoprotein E genotype and plasma lipid transport : insight into the role of the E4 allele from populational studies. Atherosclerosis, v.106, p.119
  12. A.P. Surguchov, S. Liu, W. Patsch. 1995. Simple non-radioactive methods of analysis of polymorphic markers flanking human apolipoprotein C-III gene. Disease Markers, v. 12, pp. 167 - 174
  13. Y.Ch. Lin-Lee, S. Soyal, S. Sanders, A. Surguchov, W. Patsch, 1995 Thyroid hormone influences conditional transcript elongation of the apolipoprotein A-I gene in rat liver. J. Lipid Research , v. 36, pp. 1586-1595.
  14. A.P. Surguchov, G.P. Page, L. Smith, W. Patsch, E. Boerwinkle. 1996. Polymorphic markers in apo-lipoprotein C-III gene flanking regions and hyper- lipoproteinemia. Arteriosclerosis, Thrombosis and Vascular Biology, v.16, 8, pp.941-948
  15. I.G. Surgucheva, W. Baehr, A. Surguchov. 1997. Differential effect of expression of heterologous genes in baculovirus transfer vector on the level of baculovirus protein expression. Mol Biol of the Cell, 139, 806
  16. Surguchov, I.Surgucheva, K. Howes, W. Baehr. 1999. Synoretin - a new retina protein belonging to the synuclein family. Mol Cell Neurosci, 13, 95-103.
  17. Surguchov, B. McMahon, E. Masliah, I. Surgucheva. 2001. Synucleins in ocular tissues. J Neurosci Res, 65, 68-77
  18. A Surguchov, RE. Palazzo, and I Surgucheva. 2001. Gamma synucleins: subcellular localization in neuronal and non-neuronal cells and effect on signal transduction. Cell Motility and Cytoskeleton, 2001, 49, 218-228
  19. Pronin AN, Morris AJ, Surguchov A, Benovic JL. 2000. Synucleins are a novel class of substrates for G protein-coupled receptor kinases. J Biol Chem., 275, 26515-26522
  20. Surgucheva I., McMahan B, F. Ahmed , Tomarev S, Wax MB, Surguchov A. 2002. Synucleins in glaucoma: implication of gamma-synuclein in glaucomatous alterations in the optic nerve. J Neurosci Res, 68: 97-106.
  21. Surgucheva I, Sivak, JM, Fini ME, Palazzo RE and Surguchov AP. 2003. Effect of gamma-synuclein overexpression on matrix metalloproteinases in retinoblastoma Y79 cells. Arch Biochem Biophys. 410:167-176.
  22. Maurage CA, Ruchoux MM, De Vos R, Surguchov A, Destee A. 2004. Retinal involvement in dementia with Lewy bodies: A clue to hallucinations? Ann Neurol. 54(4):542-7.
  23. Snyder HM, Mensah K, Surgucheva I, Festoff B, Surguchov A, Wolozin B. 2005. b-Synuclein prevents proteasomal inhibition by α-synuclein but not γ-synuclein. J Biol Chem, 280(9):7562-9.
  24. Surgucheva, B. Yue, BC Park, S Tomarev and A. Surguchov. 2005. Interaction of myocilin with gamma-synuclein and its role in neurodegeneration in glaucoma. Cellular Molecular Neurobiology, 25, 6, 1009-1033.
  25. Surgucheva I, Ninkina N, Buchman VL, Grasing K, A. Surguchov. 2005. Protein aggregation in retinal cells and approaches to cell protection. Cellular Molecular Neurobiology, 25, 6, 1051-1066.

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