Dr. Shengmin Sang

Center for Excellence in Post-Harvest Technologies

North Carolina A&T State University, USA

Associate Professor

Department of Food, Bioprocessing & Nutrition Sciences

North Carolina State University, USA

Adjunct Professor



1999 Ph.D., Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China

1994 B.Sc., Department of Chemistry, Shandong Normal University, China

Publications (selected)

  1. Chiou, Y.S.; Ma, N.J.;Sang, S.; Ho, C.T.; Wang, Y.J.; Pan, M.H.Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice.J. Agric. Food Chem.2012, 60(13), 3441-3451.
  2. Chen, H.; Lv, L.; Soroka, D.; Warin, R.F.; Parks, T.A.; Hu, Y.; Zhu, Y.; Chen, X.;Sang, S.Metabolism of [6]-shogaol in mice and in cancer cells.Drug Metab. Dispos.2012, 40(4), 742-753.
  3. Chen, H.; Parks, T.A.; Chen, X.; Gillitt, N.; Jobin, C.;Sang, S.Structural identification of mouse fecal metabolites of theaflavin 3, 3'-digallate using liquid chromatography tandem mass spectrometry.J. Chromatogr A.2011, 1218, 7297-7306.
  4. Zhu, Y.; Conklin, D.; Chen, H.; Wang, L.;Sang, S.5-Alk(en)ylresorcinols as the major active components in wheat bran inhibit human colon cancer cell growth.Bioorg. Med. Chem.2011, 19(13), 3973-3982.
  5. Lv, L.S.; Shao, X.; Chen, H.; Ho, C.T.;Sang, S.Genisteininhibits advanced glycation end products formation by trapping methylglyoxal.Chem. Res. Toxicol. 2011, 24(4), 579-586.
  6. Lv, L.S.; Chen, H.; Ho, C.T.;Sang, S.Chemical Components of the Roots of Noni(Morinda citrifolia)and Their Cytotoxic Effects.Fitoterapia2011, 8(4), 704-708.
  7. Sang, S.; Lambert, J.D.; Ho, C.T.; Yang, C.S. The chemistry and biotransformation of tea constituents.Pharm. Res.2011, 64, 87-99.
  8. Shao, X.; Lv, L.; Parks, T.; Wu, H.; Ho, C.T.;Sang, S.Quantitative analysis of ginger components in commercial products usingliquid chromatography with electrochemical array detection. J. Agric. Food Chem.2010, 58(24), 12608-12614.
  9. Ibarra, A.; Bai, N.S.; He, K.; Bily, A.; Cases, J.; Roller, M.;Sang, S.Fraxinus excelsiorseed extract FraxiPure™ limits weight gain and hyperglycemia in high-fat diet induced obese and diabetic mice.Phytomedicine2010, 18(6), 479-486.
  10. Lambert, J.D.;Sang, S.; Hong, J.; Yang, C.S. Anticancer and anti-inflammatory effects of cysteine metabolites of the green tea polyphenol, (-)-epigallocatechin-3-gallate.J. Agric. Food Chem.201058(18), 10016-10019.
  11. Shao, X.; Chen, X.;Badmaev, V.; Ho, C.T.;Sang, S.Structural identification of mouse urinary metabolites of pterostilbene using liquid chromatography tandem mass spectrometry.Rapid Commun Mass Spectrom2010, 24(12), 1770-1778.
  12. Wu, H.; Hsieh, M.C.; Lo, C.Y.; Liu, C.B.;Sang, S.; Ho, C.T.; Pan, M.H. 6-Shogaol is more effective than 6-gingerol and curcumin in inhibiting 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in mice.Mol Nutr Food Res.2010, 54(9), 1296-1306.
  13. Lv, L.S.; Shao, X.; Wang, L.Y.; Huang, D.R.; Ho, C.T.;Sang, S.Stilbene glucoside fromPolygonum multiflorumThunb: A novel natural inhibitor of advanced glycation end products formation by trapping of methylglyoxal.J. Agric. Food Chem.2010, 58 (4), 2239-2245.
  14. Sang, S.; Hong, J.; Wu, H.; Liu, J.; Yang, C.S.; Pan, M.H.; Ho, C.T.Increased Growth Inhibitory Effects on Human Cancer Cells and Anti-Inflammatory Potency of Shogaols from Zingiber officinale Relative to Gingerols.J. Agric. Food Chem.2009, 57 (22), 10645-10650.
  15. Wu, H.; Dushenkov, S.; Ho, C. T.;Sang, S.Novel acetylated flavonoid glycosides fromAllium ursinum.Food Chem.2009115(2), 592-595.
  16. Yang, C. S.; Lambert, J.D.;Sang, S.Antioxidative and anti-carcinogetic activities of tea polyphenols.Arch Toxicol.2008, 83(1), 11-21.
  17. Sang, S.; Yang, C.S.Structure identification of novel glucoside and glucuronide metabolite of (-)-epigallocatechin-3-Gallate in mouse urine using liquid chromatography/electrospray ionization tandem mass spectrometry.Rapid Commun Mass Spectrom2008, 22 (22), 3693-3699.
  18. Shao, X.; Bai, N.S.; He, K.; Ho, C.T.; Yang, C.S.;Sang, S.Apple polyphenols, phloretin and phloridzin: new trapping agents of reactive dicarbonyl species.Chem. Res. Toxicol. 2008, 21 (10):2042-2050.
  19. Sang, S.; Lee, M.J.; Yang, I.; Buckley, B.; Yang, C.S.Human Urinary Metabolite Profile of Tea Polyphenols analyzed by Liquid Chromatography/electrospray Ionization Tandem Mass Spectrometry with Data-dependent Acquisition.Rapid Commun Mass Spectrom200822(10):1567-1578.
  20. Yang, C.S.;Sang, S.; Lambert, J.D.; Lee, M.J.Bioavailability issues in studying the health effects of plant polyphenolic compounds.Mol Nutr Food Res.200852(S1), 139-151.
  21. Lambert, J.D.;Sang, S.; Yang, C.S.N-Acetylcysteine enhances the lung cancer inhibitory effect of epigallocatechin-3-gallate and forms a new adduct.Free Radical Bio. Med.2008, 44(6), 1069-1074.
  22. Lo, C.Y.; Li, S.; Wang, Y.; Tan, D.; Pan, M.X.;Sang, S.; Ho, C.T.Reactive Dicarbonyl Compounds and 5-(Hydroxymethyl)-2-furfural in Carbonated Beverages Containing High Fructose Corn Syrup.Food Chem.2008, 107(3), 1099-1105.
  23. Sang, S.; Shao, X.; Bai, N.; Yang, C.S.; Ho, C.T. Tea Polyphenol (-)-Epigallocatechin 3-Gallate: a New Trapping Agent of Reactive Dicarbonyl Species.Chem. Res. Toxicol. 2007,20(12):1862-1870.
  24. Sang, S.; Yang, H.; Buckley, B.; Ho, C.T.; Yang, C.S.Autoxidative quinone formationin vitroand metabolite formationin vivofrom tea polyphenol (-)-epigallocatechin-3-gallate: studied by real-time mass scanning combined with tandem mass ion mapping.Free Radical Bio. Med.2007, 43(3), 362-371.
  25. Li, S.;Sang, S.; Pan, M.X.; Lai, C.S.; Lo, C.; Yang, C.S.; Ho, C.T. Anti-inflammatory property of the urinary metabolites of nobiletin in mouse.Bioorg Med Chem Lett.200717(18), 5177-5181.

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