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Biography
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Dr. Shengmin Sang

Center for Excellence in Post-Harvest Technologies

North Carolina A&T State University, USA

Associate Professor

Department of Food, Bioprocessing & Nutrition Sciences

North Carolina State University, USA

Adjunct Professor


Email: ssang@ncat.edu


Qualifications

1999 Ph.D., Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China

1994 B.Sc., Department of Chemistry, Shandong Normal University, China

Publications (selected)

  1. Chiou, Y.S.; Ma, N.J.;Sang, S.; Ho, C.T.; Wang, Y.J.; Pan, M.H.Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice.J. Agric. Food Chem.2012, 60(13), 3441-3451.
  2. Chen, H.; Lv, L.; Soroka, D.; Warin, R.F.; Parks, T.A.; Hu, Y.; Zhu, Y.; Chen, X.;Sang, S.Metabolism of [6]-shogaol in mice and in cancer cells.Drug Metab. Dispos.2012, 40(4), 742-753.
  3. Chen, H.; Parks, T.A.; Chen, X.; Gillitt, N.; Jobin, C.;Sang, S.Structural identification of mouse fecal metabolites of theaflavin 3, 3'-digallate using liquid chromatography tandem mass spectrometry.J. Chromatogr A.2011, 1218, 7297-7306.
  4. Zhu, Y.; Conklin, D.; Chen, H.; Wang, L.;Sang, S.5-Alk(en)ylresorcinols as the major active components in wheat bran inhibit human colon cancer cell growth.Bioorg. Med. Chem.2011, 19(13), 3973-3982.
  5. Lv, L.S.; Shao, X.; Chen, H.; Ho, C.T.;Sang, S.Genisteininhibits advanced glycation end products formation by trapping methylglyoxal.Chem. Res. Toxicol. 2011, 24(4), 579-586.
  6. Lv, L.S.; Chen, H.; Ho, C.T.;Sang, S.Chemical Components of the Roots of Noni(Morinda citrifolia)and Their Cytotoxic Effects.Fitoterapia2011, 8(4), 704-708.
  7. Sang, S.; Lambert, J.D.; Ho, C.T.; Yang, C.S. The chemistry and biotransformation of tea constituents.Pharm. Res.2011, 64, 87-99.
  8. Shao, X.; Lv, L.; Parks, T.; Wu, H.; Ho, C.T.;Sang, S.Quantitative analysis of ginger components in commercial products usingliquid chromatography with electrochemical array detection. J. Agric. Food Chem.2010, 58(24), 12608-12614.
  9. Ibarra, A.; Bai, N.S.; He, K.; Bily, A.; Cases, J.; Roller, M.;Sang, S.Fraxinus excelsiorseed extract FraxiPure™ limits weight gain and hyperglycemia in high-fat diet induced obese and diabetic mice.Phytomedicine2010, 18(6), 479-486.
  10. Lambert, J.D.;Sang, S.; Hong, J.; Yang, C.S. Anticancer and anti-inflammatory effects of cysteine metabolites of the green tea polyphenol, (-)-epigallocatechin-3-gallate.J. Agric. Food Chem.201058(18), 10016-10019.
  11. Shao, X.; Chen, X.;Badmaev, V.; Ho, C.T.;Sang, S.Structural identification of mouse urinary metabolites of pterostilbene using liquid chromatography tandem mass spectrometry.Rapid Commun Mass Spectrom2010, 24(12), 1770-1778.
  12. Wu, H.; Hsieh, M.C.; Lo, C.Y.; Liu, C.B.;Sang, S.; Ho, C.T.; Pan, M.H. 6-Shogaol is more effective than 6-gingerol and curcumin in inhibiting 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in mice.Mol Nutr Food Res.2010, 54(9), 1296-1306.
  13. Lv, L.S.; Shao, X.; Wang, L.Y.; Huang, D.R.; Ho, C.T.;Sang, S.Stilbene glucoside fromPolygonum multiflorumThunb: A novel natural inhibitor of advanced glycation end products formation by trapping of methylglyoxal.J. Agric. Food Chem.2010, 58 (4), 2239-2245.
  14. Sang, S.; Hong, J.; Wu, H.; Liu, J.; Yang, C.S.; Pan, M.H.; Ho, C.T.Increased Growth Inhibitory Effects on Human Cancer Cells and Anti-Inflammatory Potency of Shogaols from Zingiber officinale Relative to Gingerols.J. Agric. Food Chem.2009, 57 (22), 10645-10650.
  15. Wu, H.; Dushenkov, S.; Ho, C. T.;Sang, S.Novel acetylated flavonoid glycosides fromAllium ursinum.Food Chem.2009115(2), 592-595.
  16. Yang, C. S.; Lambert, J.D.;Sang, S.Antioxidative and anti-carcinogetic activities of tea polyphenols.Arch Toxicol.2008, 83(1), 11-21.
  17. Sang, S.; Yang, C.S.Structure identification of novel glucoside and glucuronide metabolite of (-)-epigallocatechin-3-Gallate in mouse urine using liquid chromatography/electrospray ionization tandem mass spectrometry.Rapid Commun Mass Spectrom2008, 22 (22), 3693-3699.
  18. Shao, X.; Bai, N.S.; He, K.; Ho, C.T.; Yang, C.S.;Sang, S.Apple polyphenols, phloretin and phloridzin: new trapping agents of reactive dicarbonyl species.Chem. Res. Toxicol. 2008, 21 (10):2042-2050.
  19. Sang, S.; Lee, M.J.; Yang, I.; Buckley, B.; Yang, C.S.Human Urinary Metabolite Profile of Tea Polyphenols analyzed by Liquid Chromatography/electrospray Ionization Tandem Mass Spectrometry with Data-dependent Acquisition.Rapid Commun Mass Spectrom200822(10):1567-1578.
  20. Yang, C.S.;Sang, S.; Lambert, J.D.; Lee, M.J.Bioavailability issues in studying the health effects of plant polyphenolic compounds.Mol Nutr Food Res.200852(S1), 139-151.
  21. Lambert, J.D.;Sang, S.; Yang, C.S.N-Acetylcysteine enhances the lung cancer inhibitory effect of epigallocatechin-3-gallate and forms a new adduct.Free Radical Bio. Med.2008, 44(6), 1069-1074.
  22. Lo, C.Y.; Li, S.; Wang, Y.; Tan, D.; Pan, M.X.;Sang, S.; Ho, C.T.Reactive Dicarbonyl Compounds and 5-(Hydroxymethyl)-2-furfural in Carbonated Beverages Containing High Fructose Corn Syrup.Food Chem.2008, 107(3), 1099-1105.
  23. Sang, S.; Shao, X.; Bai, N.; Yang, C.S.; Ho, C.T. Tea Polyphenol (-)-Epigallocatechin 3-Gallate: a New Trapping Agent of Reactive Dicarbonyl Species.Chem. Res. Toxicol. 2007,20(12):1862-1870.
  24. Sang, S.; Yang, H.; Buckley, B.; Ho, C.T.; Yang, C.S.Autoxidative quinone formationin vitroand metabolite formationin vivofrom tea polyphenol (-)-epigallocatechin-3-gallate: studied by real-time mass scanning combined with tandem mass ion mapping.Free Radical Bio. Med.2007, 43(3), 362-371.
  25. Li, S.;Sang, S.; Pan, M.X.; Lai, C.S.; Lo, C.; Yang, C.S.; Ho, C.T. Anti-inflammatory property of the urinary metabolites of nobiletin in mouse.Bioorg Med Chem Lett.200717(18), 5177-5181.


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