Prof. Guanghui Liu

Chinese Academy of Sciences, Institute of Biophysics, China



2007 Ph.D., Graduate University of Chinese Academy of Sciences, China

2002 B.S., Peking University Health Science Center, China

Publications (Selected)

  1. Li M1, Liu GH1, Belmonte JC. Navigating the epigenetic landscape of pluripotent stem cells.Nat. Rev. Mol. Cell. Biol. 2012, in press. (1equal contribution)
  2. Giorgetti A1, Marchetto MC1, Li M1, Yu D, Fazzina R, Mu Y, Adamo A, Paramonov I, Cardoso JC, Monasterio MB, Bardy C, Cassiani-Ingoni R, Liu GH, Gage F, Belmonte JC. Cord Blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc. ProcNatlAcadSci U S A. 2012. in press
  3. Cai N1, Li M1, Qu J1, Liu GH*, Belmonte JC*. Post-translational modulation of pluripotency.J Mol Cell Biol. 2012 Jun 7.(*Corresponding author)
  4. Liu GH1*, Yi F1,Suzuki K, Qu J, Belmonte JC*. Induced neural stem cells: a new tool for studying neural development and neurological disorders.Cell Res. 2012. May 1. doi: 10.1038/cr.2012.73. (*Corresponding author)
  5. Liu GH*, Li M, Qu J, Belmonte JC*. Gating neural development and aging via nuclear pores. Cell Res. 2012 Mar; doi: 10.1038/cr.2012.35.(*Corresponding author)
  6. Gu Y, Liu GH*, Belmonte JC*. Gametogenesis in a dish.Cell Res.2012. May; doi:10.1038 / cr.2012. (*Corresponding author)
  7. Xu X1, Qu J1, Suzuki K, Li M, Zhang W, Liu GH*, Belmonte JC*. Reprogramming based gene therapy for inherited red blood cell disorders. Cell Res. 2012. 22(6):941-4. (*Corresponding author)
  8. Yi F, Liu GH*, Belmonte JC*. Rejuvenating liver and pancreas through cell transdifferentiation.Cell Res.2012. 22(4):616-9. (*Corresponding author)
  9. Liu GH, Sancho-Martinez I, Belmonte JC. Cut and Paste: restoring cellular function by gene correction. Cell Res. 2012;22(2):283-4.
  10. Wang P1, Zhang W1, Yang J, Qu J, Liu GH*.Higher-order genomic organization in pluripotent stem cells.Protein Cell.2012 Jun 6. (*Corresponding author)
  11. Zhang W1, Guan Di1, Qu J, Zhang W, Liu GH*. Non-viral iPSC: a safe way for therapy? Protein Cell. 2012. 3(4):241-5. (*Corresponding author)
  12. Yi F, Liu GH*, Belmonte JC*. Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapy.Protein Cell. 2012. 3(4):246-50. (*Corresponding author)
  13. Zhang W1, Duan S1, Li Y, Xu X, Qu J, Zhang W, Liu GH*. Converted neural cells: induced to a cure? Protein Cell. 2012.3(2):91-7. (*Corresponding author)
  14. Zhang W1, Ding Z1, Liu GH*.Evolution of iPSC disease models.Protein Cell. 2012;3:1-4. (*Corresponding author)
  15. Liu GH,Barkho BZ, Ruiz S, Diep D, Qu J, Yang SL, Panopoulos AD, Suzuki K, Kurian L, Walsh C, Thompson J, Boue S, Fung HL, Sancho-Martinez I, Zhang K, Iii JY, Belmonte JC. Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome.Nature. 2011; 14;472: 221-5 Evaluated by“Faculty of 1000” (
  16. Liu GH1, Suzuki K1, Qu J1, Sancho-Martinez I, Yi F, Li M, Kumar S, Nivet E, Kim J, Soligalla RD, Dubova I, Goebl A, Plongthongkum N, Fung HL, Zhang K, LoringJ,Laurent L, and Belmonte JC. Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs.Cell Stem Cell, 2011, 8(6):688-94. Highlighted byNature (Nature 474,8. doi:10.1038/474008c) Highlighted by Cell Stem Cell (Cell Stem Cell 9, 2: 93-94)
  17. Li M, Suzuki K, Qu J, Saini P, Dubova I, Yi F, Lee J, Sancho-Martinez I, Liu GH, Belmonte JC. Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs.Cell Res2011. 21(12):1740-4.
  18. Pan H1, Zhang W1, Zhang W, Liu GH*. Find and Replace: editing human genome in pluripotent stem cells. Protein Cell. 2011; 2(12):950-6. (*Corresponding author)
  19. Zhang W, Liu GH*.Pluripotent stem cells and human diseases. ProgBiochemBiophys. 2011; 38(11): -6. (*Corresponding author)
  20. Liu GH1*,Qu J1, Carmack AE, Kim HB, Chen C, Ren H, Morris AJ, Finck BN, Harris TE*. Lipin proteins form homo- and hetero-oligomers. Biochem J. 2010; 432(1):65-76. (*Corresponding authors)