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Biography
Hani El-Nezami

Dr. Hani El-Nezami

University of Hong Kong, China


Email: elnezami@hku.hk


Qualifications


1999 Doctor of Philosophy (Ph.D.), Nutritional Toxicology, RMIT-University, Melbourne, Australia

1995 Master of Applied Science, Nutritional Toxicology, RMIT-University, Melbourne, Australia

1985 Bachelor of Science, Biochemistry, University of Alexandria, Alexandria, Egypt


Publications (Selected)

  1. El-Nezami, H. S., Nicoletti, G., Neal, G. E., Donohue, D. and Ahokas, J. T., 1995. Aflatoxin M1 in human breast milk samples from Victoria, Australia and Thailand. Food. Chem. Toxicol., 33, 173-179. (2.321, 35/75)
  2. El-Nezami, H. S., S. Salminen and J.T. Ahokas. 1996. Biologic control of food carcinogen using Lactobacillus GG.Nutr Today. 31, 41-43.
  3. El-Nezami H. S., P.E. Kankaanpää, S. Salminen and J.T. Ahokas. 1998 (a). Ability of dairy strains of lactic acidbacteria to bind food carcinogens. Food Chem. Toxicol., 36, 321-326. (2.321, 35/75)
  4. El-Nezami H. S., P.E. Kankaanpää, S. Salminen and J.T. Ahokas. 1998 (b). Physico-chemical alterations enhance the ability of dairy strains of lactic acid bacteria to remove aflatoxins from contaminated media. J. Food Prot., 61,466-468. (1.763, 27/107)
  5. Kiriavainen, P., H. ElNezami, J. Ahokas, S. Salminen and P. Wright. 1999. The effect of orally administered viable Lactobacillus GG and Propionibacterium JS on mouse lymphocyte proliferation. Clin. Diag. Lab. Immunol., 6, 799-802. (2.237, 43/91)
  6. Kiriavainen, P., H. El-Nezami, J. Ahokas, S. Salminen and P. Wright. 1999. The Effect of Orally Administered Viable Probiotic and Dairy Lactobacilli on Mouse Lymphocyte Proliferation. FEMS Immunol.Med. Microbiol., 26, 131-135. (1.972, 58/91)
  7. El-Nezami, H. S., H. Mykkänen, P., Kankaanpää, S. Salminen and J. T., Ahokas. 2000. Ability of Lactobacillus and Propionibacterium strains to remove aflatoxin B, from the chicken duodenum. 2000. J. Food. Prot., 63: 549-552. (1.763, 27/107)
  8. El-Nezami, H. S., H. Mykkänen, P., Kankaanpää, T., Suomalainen, J T., Ahokas and S. Salminen. 2000. The ability of a mixture of Lactobacillus and Propionibacterium to influence the faecal recovery of aflatoxins in healthy Egyptian volunteers: A pilot clinical study. Biosci. Microflora, 19: 41-45.
  9. Kankaanpaa, P., E. Tuomola, H. El-Nezami, J. Ahokas, and S. Salminen. 2000. Binding of aflatoxin B1 alters the adhesion properties of Lactobacillus rhamnosus strain GG in a Caco-2 model. J Food Prot., 63: 412-414. (1.763, 27/107)
  10. Pieridis, M, H. El-Nezami, K. Peltonen, S. Salminen and J. Ahokas. 2000. Ability of dairy strains of lactic acid bacteria to bind aflatoxin M1 in a food model. J Food Prot., 63, 645-650. (1.763, 27/107)
  11. Peltonen, K., H. El-Nezami, S. Salminen and J. Ahokas. 2000. Binding of aflatoxin B1 by probiotic bacteria. J. Sci. Food Agr., 80, 1942-1945. (1.333, 6/35)
  12. Haskard C., H. El-Nezami, P. Kankaanpää, S. Salminen, and J. T. Ahokas. 2001. Surface binding of aflatoxin B1 by lactic acid bacteria. Appl. Environ. Microbiol., 67:3086-3091. (3.801, 21/91)
  13. Peltonen K, H. El-Nezami, C. Haskard, J. Ahokas, and S. Salminen. 2001. Aflatoxin B1 binding by dairy strains of lactic acid bacteria and bifidobacteria. J. Dairy Sci., 84:2152-6. (2.486, 1/45)
  14. El-Nezami, H. S., Chrevatidis, A., Auriola, S., Salminen, S. and Mykkänen, H. Removal of common Fusarium toxins in vitro by strains of Lactobacillus and Propionibacterium. 2002. Food Addit. Contam., 19: 680-686. (1.810, 26/107)
  15. El-Nezami, H. S., Polychronaki, N, Salminen, S. and Mykkänen, H. 2002. Binding rather than metabolism may explain the interaction of two food grade Lactobacillus strains with zearalenone and its derivative α-zearalenol. Appl. Environ. Microbiol., 68: 3545-3549. (3.801, 21/91)
  16. El-Nezami, H. S, C. Haskard, E. Salminen, H. Mykkänen, J. Ahokas, and S. Salminen. 2002. Lactic acid bacteria and bifidobacteria can reduce dietary exposure to aflatoxins. Br. J. Nut., 88: S115-S116. (2.764, 15/59)
  17. El-Nezami, H. S., Salminen, S. and Mykkänen, H. 2002. Probiotic bacteria-mycotoxins interactions: an approach to enhance food safety. Pol. J. Food. Nutr., Sci., 11:39-43.
  18. Lee, Y. K., El-Nezami, H. S., Haskard, C. A., Gratz, S., Puong, K. Y., Salminen S. and Mykkänen, H. 2003. A Kinetic approach to study mechanism of adsorption and desorption of aflatoxin B1 by viable and heat-treated bacteria. J. Food Prot., 66: 426-431. (1.763, 27/107)
  19. Gråsten, S., Liukkonen, K.H., Chevratidis, A., El-Nezami, H., Poutanen, K., Mykkänen, H. 2003. Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans. Nutr. Res. 23: 1503-1514. (0.866, 48/59)
  20. El-Nezami, H. S., Polychronaki, N, Lee, Y. K., Haskard, C. A., Juvonen, R., Salminen S. and Mykkänen, H. 2004. Chemical moieties and interactions involved in the binding of zearalenone to the surface of Lactobacillus rhamnosus strain GG. J Agr. Food Chem. 52:4577-4581. (2.562, 2/35)
  21. Gratz, S., Mykkänen, H., Ouwehand, A. C., R. Juvonen, S. Salminen and El-Nezami, H. 2004. Intestinal mucus alters the ability of probiotic bacteria to bind aflatoxin B1. Appl. Environ. Microbiol., 70:6306-6308. (3.801, 21/91)
  22. Mykkänen H, Zhu H, Salminen E, Juvonen RO, Ling W, Jing M, Polychronaki N, Hynninen H, Mykkänen O, Salminen S, El-Nezami H. 2005. Fecal and urinary excretion of aflatoxin B1 metabolites (AFQ1, AFM1, AFB-N7-guanine) in young Chinese males. Int J Cancer .,115:879-84. (4.734, 30 /143)
  23. Polychronaki, N., P, C. T., Mykkanen, H., Gong, Y., Amra, H., Abdel-Wahhab, M., and El-Nezami, H. 2006. Determinants of aflatoxin M1 in breast milk in a selected group of Egyptian mothers. Food addit. contam, 23: 700-708. (1.810, 26/107)
  24. El-Nezami, H. S., Polychronaki, N. N., Ma, J., Zhu, H., Ling, W., Salminen, E. K., Juvonen, R. O., Salminen, S. J., Poussa, T., and Mykkanen, H. M. Probiotic supplementation reduces a biomarker for increased risk of liver cancer in young men from Southern China. 2006. Am. J. Clin. Nutr, 83: 1199-1203. (6.74, 3/59)
  25. Gratz, S., Taubel, M., Juvonen, R. O., Viluksela, M., Turner, P. C., Mykkanen, H., and El-Nezami, H. 2006. Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B(1) in rats. Appl. Environ. Microbiol., 72: 7398-7400. (3.801, 21/91)
  26. Polychronaki, N., West, R.M., Turner, P.C., Amra, H., Abdel-Wahhab, M., Mykkanen, H. and El-Nezami, H. (2007) A longitudinal assessment of aflatoxin M1 excretion in breast milk of selected Egyptian mothers. Food Chem Toxicol, 45, 1210-5. (2.321, 35/75)
  27. Gratz, S., Wu, Q.K., El-Nezami, H., Juvonen, R.O., Mykkanen, H. and Turner, P.C. (2007) Lactobacillus rhamnosus strain GG reduces aflatoxin B1 transport, metabolism, and toxicity in Caco-2 Cells. Appl Environ Microbiol, 73, 3958-64. (3.801, 21/91)
  28. Gråsten, S. M., Juntunen, K. S., Mättö, J., Mykkänen, O. T., El-Nezami, H., Adlercreutz, H., Poutanen, K. S., Mykkänen, H. M. (2007) High-fiber rye bread improves bowel function in postmenopausal women but does not cause other putatively positive changes in the metabolic activity of intestinal microbiota. Nutrition Res, 27, 454-61. (0.866, 48/59)
  29. Anwar, W.A., Khaled, H.M., Amra, H.A., El-Nezami, H. and Loffredo, C.A. (2008) Changing pattern of hepatocellular carcinoma (HCC) and its risk factors in Egypt: possibilities for prevention. Mutat Res, 659, 176-84. (5.192, 3/75)
  30. Halttunen, T., Collado, M.C., El-Nezami, H., Meriluoto, J. and Salminen, S. (2008) Combining strains of lactic acid bacteria may reduce their toxin and heavy metal removal efficiency from aqueous solution. Lett Appl Microbiol, 46, 160-5. (1.679, 62/91)
  31. Liu, C., Sun, M., Yan, X., Han, L., Zhang, Y., El-Nezami, H. and Liu, P. (2008) Inhibition of hepatic stellate cell activation following Yinchenhao decoction administration to dimethylnitrosamine-treated rats. Hepatol Res, 38, 919-29. (1.562, 40/55)
  32. Polychronaki, N., Wild, C.P., Mykkanen, H., Amra, H., Abdel-Wahhab, M., Sylla, A., Diallo, M., El-Nezami, H. and Turner, P.C. (2008) Urinary biomarkers of aflatoxin exposure in young children from Egypt and Guinea. Food Chem Toxicol, 46, 519-26. (2.321, 35/75)
  33. Turner, P.C., Wu, Q.K., Piekkola, S., Gratz, S., Mykkanen, H. and El-Nezami, H. (2008) Lactobacillus rhamnosus strain GG restores alkaline phosphatase activity in differentiating Caco-2 cells dosed with the potent mycotoxin deoxynivalenol. Food Chem Toxicol, 46, 2118-23. (2.321, 35/75)
  34. Hatakka, K., Holma, R., El-Nezami, H., Suomalainen, T., Kuisma, M., Saxelin, M., Poussa, T., Mykkanen, H. and Korpela, R. (2008) The influence of Lactobacillus rhamnosus LC705 together with Propionibacterium freudenreichii ssp. shermanii JS on potentially carcinogenic bacterial activity in human colon. Int J Food Microbiol, 128, 406-410. (3.486, 34/91)
  35. Partanen, H.A., El-Nezami, H.S., Leppanen, J.M., Myllynen, P.K., Woodhouse, H.J. and Vahakangas, K.H. (2010) Aflatoxin B1 transfer and metabolism in human placenta. Toxicol Sci. 113:216-25.
  36. Gratz, S., Mykkanen, H. and El-Nezami, H. (2010) Probiotics and gut health : A special focus on liver disease. World J Gastero. 16:403-10. (2.081, 33/55)
  37. Salminen, S., Nybom, S., Meriluoto, J., Collado, M., Vesterlund, S. and El-Nezami, H. (2010) Probiotic pathogen/toxin interaction - benefits to human health and nutrition?. Curr op Biotech. 21, 157-167. (7.485, 5/144)
  38. Uzuner H, Fan TP, Dias A, Guo DA, El-Nezami HS, Xu Q.Establishing an EU-China.
  39. consortium on traditional Chinese medicine research. (2010). Chin Med. 5:42-47 (1.79).
  40. Storvik M., Huuskonen P., Kyllonen T., Lehtonen S., El-Nezamy H.S., Auriola S. and Pasanen M. Aflatoxin B1 – A Potential Endocrine Disruptor – Up-regulates Cyp19a1 In Jeg-3 Cells, Toxicology Letters, 2011, 202, 161-167.
  41. Gratz S., John Wallace R. and El-Nezami H.S. Recent Perspectives On The Relations Between Fecal Mutagenicity, Genotoxicity, And Diet, Frontiers in Pharmacology, 2011, 2, 1-9.
  42. Wang Q.L., Wu Q., Tao Y.Y., Liu C.H. and El-Nezamy H.S. Salvianolic Acid-b Modulates The Expression Of drug-metabolizing Enzymes In Hepg2 Cells, Hepatobiliary Pancreat Dis. Int, 2011, 10.
  43. Peng J, Li D, Chan YK, Chen Y, Lamb JR, Tam PK, El-Nezami H: Effects of water uptake on melamine renal stone formation in mice. Nephrol Dial Transplant 2011.
  44. Partanen H, Vahakangas K, Woo CS, Auriola S, Veid J, Chen Y, Myllynen P, El Nezami H: Transplacental transfer of melamine. Placenta 2012, 33(1):60-66.
  45. Woo CS, Partanen H, Myllynen P, Vahakangas K, El-Nezami H: Fate of the teratogenic and carcinogenic ochratoxin A in human perfused placenta. Toxicol Lett 2012, 208(1):92-99.
  46. Piekkola, S., Turner, P. C., Abdel-Hamid, M., Ezzat, S., El-Daly, M., El-Kafrawy, S., Savchenko, E., Poussa, T., Woo, J. C., Mykkanen, H. and El-Nezami, H. (2012). Characterisation of aflatoxin and deoxynivalenol exposure among pregnant Egyptian women. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 29(6), 962-71.