Prof. Alireza G. Senejani

Yale University School of Medicine, USA

Associate Research Scientist



2013 Post doctorate, Yale University, USA

2007 Ph.D., Genetics, University of Connecticut, USA

2000 M.Sc., Biotechnology, Mannheim University of Applied Science, Germany

1998 B.Sc., Biochemistry, Aligarh University, India

Publications (Selected)

  1. Lokanga R., Senejani A.G., Sweasy J.B., Usdin K. “Heterozygosity for a hypomorphic Polβ mutation reduces the expansion frequency in a mouse model of the repeat expansion disease Fragile X syndrome” 2015 PLoS Genetics. 2015 Apr 17; 11(4).
  2. Park H.J., Kim D.H., Choi J.Y., Kim W.J., Kim J.Y., Senejani A.G., Hwang S.S., Kim, L.K., Tobiasova Z., Lee G.R., Craft J., Choi J., Bothwell A.L., Choi J. M. “PPARγ negatively regulates T cell activation to prevent follicular helper T cells and germinal center formation” PLoS One 2014 June 12; 9(6).
  3. Senejani A.G., Liu Y., Kidane D., Maher S.E., Zeiss C.J., Park H., Kashgarian M., McNiff J.M., Zelterman D., Bothwell A., Sweasy J.B. “Mutation of A DNA Repair Enzyme Causes Lupus in Mice” Cell reports (CELL PRESS) 2014 Jan 16; 6(1): 1-8. doi: 10.1016/j.celrep.2013.12.017. Epub 2014 Jan 2.
  4. Ray S., Menezes M.R., Senejani A., Sweasy J.B. “Cellular Roles of DNA Polymerase Beta” Yale J Biol Med 2013 Dec 13; 86(4): 463-469.
  5. Sjolund A, Senejani AG, Sweasy JB “MBD4 and TDG: Multifaceted DNA Glycosylases With Ever Expanding Biological Roles” (submitted).
  6. Senejani AG, Dalal S, Liu Y, Nottoli, T, McGrath J, Clairmont CS, Sweasy JB “Y265C DNA Polymerase Beta Knockin Mice Survive Past Birth and Accumulate Base Excision Repair Intermediate Substrates” Proc Natl Acad Sci U S A. 2012 Apr 24; 109(17): 6632-7. Epub 2012 Apr 9.
  7. Senejani, A.G. and Sweasy, J.B.; Eukaryotic gene invasion by a bacterial mobile Insertion sequence element IS2 during cloning into a plasmid vector; Genome Intergrity. 2010 May 26; 1(1): 2.
  8. Swithers K.S., Senejani A.G, Fournier G.P., Gogarten J.P.; Conservation of intron and intein insertion sites: implications for life histories of parasitic genetic elements. BMC Evol Biol. 2009; 9: 303“ BMC Highly accessed article”.
  9. Senejani, A.G. and Gogarten, J.P.; Structural stability and endonuclease activity of PI-SceI GFP-fusion protein; Int J Biol Sci 2007; 3: 205-211.
  10. Gogarten, J.P., Senejani, A.G., Zhaxybayeva, O., Olendzenski, L. and Hilario, E.; Inteins: Structure, Function, and Evolution Annul. Review of Microbiology. 2002, 56: 263-287.
  11. Senejani, A.G., Hilario, E., and Gogarten, J.P.; The intein of the Thermoplasma A-ATPase A subunit: Structure, evolution and expression in E. coli. BMC Biochemistry 2001 2(1): 13,1-10.

Last Updated: July, 2015