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Dr. Murat Sentürk

Department of Chemistry, Science and Art Faculty

Agri Ibrahim Cecen University, Turkey

Assistant Professor


E-mail: senturkm36@gmail.com, msenturk@agri.edu.tr


Qualifications

2009 Ph.D., Biochemistry, Atatürk University, Turkey

2006 M.Sc., Biochemistry, Atatürk University, Turkey

2002 B.Sc., Chemistry, Atatürk University, Turkey


Publications (selected)

  1. Senturk, M.,Kufrevioglu, O.I., 2009. In vitro effects of some nucleoside analogue drugs on enzyme activities of carbonic anhydrase isozymes I and II from human erythrocytes. Hacettepe Journal of Biology and Chemistry. 37 (4), 289-294.
  2. Ozdemir, Z.O.,Senturk, M., Ekinci, D. 2011. Glucose 6-Phosphate Dehydrogenase Activatory Properties of Some Organic Compounds and Amino Acids. Hacettepe Journal of Biology and Chemistry. 39 (2), 157-162.
  3. Ekinci, D., Ozdemir, Z.O.,Senturk, M. 2011. Peptide Based Biological Active Molecules. Hacettepe Journal of Biology and Chemistry. 39 (4), 351-357.
  4. Senturk, M.,Gulcin, I., Ciftci, M., Kufrevioglu O.I., 2008. Dantrolene Inhibits Human Erythrocyte Glutathione Reductase. Biological & Pharmaceutical Bulletin, 31; 11,2036-2039.
  5. Tekman B., Ozdemir, H.,Senturk, M.,Ciftci, M., 2008. Purification and Characterization of Glutathione Reductase from Rainbow Trout (Oncorhynchus mykiss) Liver and Inhibition Effects of Some Metal Ions on Enzyme Activity. Comparative Biochemistry and Physiology C-Toxicology & Pharmacology, 148: 2; 117–121.
  6. Bayram, E.,Senturk, M.,Kufrevioglu, O.I., Supuran C.T., 2008. In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II. Bioorganic & Medicinal Chemistry, 16: 20; 9101–9105 .
  7. Senturk, M., Gulcin, I., Dastan, A., Kufrevioglu, O.I., Supuran, C.T., 2009. Carbonic anhydrase inhibitors: Inhibitor of human erythrocyte I and II isoenzymes with antioxidant phenolic compounds. Bioorganic & Medicinal Chemistry, 17: 8; 3207-3211.
  8. Senturk, M.,Talaz, O., Ekinci, D., Cavdar, H., Kufrevioglu, O.I., 2009. In vitro inhibition of human erythrocyte glutathione reductase by some new organic nitrates. Bioorganic & Medicinal Chemistry Letters. 19, 3661-3663.
  9. Senturk, M.,Ceyhun, S.B., Erdogan, O., Kufrevioglu, O.I., 2009. In vitro and in vivo effects of some pesticides on glucose-6-phosphate dehydrogenase enzyme activity from rainbow trout (oncorhynchus mykiss) erythrocytes. Pesticide Biochemistry and Physiology. 95, 95-99.
  10. Sahin, A.,Senturk, M.,Ciftci, M., Varoglu, E., Kufrevioglu, O.I., 2010. Effects of thallium-201 and radioactivity on human erythrocyte glucose 6-phosphate dehydrogenase activity. Nuclear Medicine and Biology. 37, 389-394.
  11. Ceyhun, S.B.,Senturk, M., Erdogan, O., Kufrevioglu, O.I. 2010. In vitro and in vivo effects of some pesticides on carbonic anhydrase enzyme from rainbow trout (oncorhynchus mykiss) gills. Pesticide Biochemistry and Physiology. 97, 177-181.
  12. Ekinci, D., Cavdar, H., Talaz, O.,Senturk, M., Supuran, C.T. 2010. Evaluation of the influences of novel organic nitrate compounds with potential anticancer capacity on the activity of carbonic anhydrase I and II isozymes.Bioorganic & Medicinal Chemistry. 18, 3559-3563.
  13. Ceyhun, S.B.,Senturk, M.,Ekinci, D., Erdogan, O., Ciltas, A., Kocaman, M. 2010. Deltamethrin attenuates antioxidant defense system and induces the expression of heat shock protein 70 in rainbow trout. Comparative Biochemistry and Physiology C-Toxicology & Pharmacology, 152, 215-223.
  14. Alp, C., Ekinci, D., Gultekin, M.S.,Senturk, M., Sahin E., Kufrevioglu O.I. 2010. A novel one-pot synthesis of new 1-tosyl pyrrol-2-one derivatives and analysis for carbonic anhydrase inhibitory potencies. Bioorganic & Medicinal Chemistry. 18, 4468-4474.
  15. Ekinci, D.,Senturk, M.,Beydemir, S., Kufrevioglu, O.I., Supuran, C.T. 2010. An alternative purification of human serum Paraoxonase 1 and Interactions with Sulfonamides. Chemical Biology & Drug Design. 76, 552–558.
  16. Ekinci, D., Ceyhun, S.B.,Senturk, M.,Erdem, D., Kufrevioglu, O.I., Supuran, C.T., 2011. Characterization and anions inhibition studies of an -carbonic anhydrase from the teleost fishDicentrarchus labrax.Bioorganic & Medicinal Chemistry. 19, 744-748.
  17. Akkemik, E., Senturk, M., Ozgeris, F.B., Taser, P., Ciftci, M. 2011. In vitro effects of some drugs on human erythrocyte glutathione reductase. Turkish Journal of Medical Sciences. 41, 235-241.
  18. Durdagi, S., Senturk, M., Ekinci, D., Balaydin, H.T., Goksu, S., Kufrevioglu, O.I., Innocenti, A., Scozzafava, A., Supuran, C.T., 2011. Kinetic and docking study of phenol-based inhibitors of carbonic anhydrase isoform I, II, IX and XII evidence a new binding mode within the enzyme active site. Bioorganic & Medicinal Chemistry. 19, 1381-1389.
  19. Senturk, M., Gulcin, I., Beydemir, S., Kufrevioglu, O.I., Supuran, C.T. 2011. In vitro inhibition of human carbonic anhydrase I and II isozymes with natural phenolic compounds. Chemical Biology & Drug Design. 77, 494-499.
  20. Ceyhun, S.B., Senturk, M., Yerlikaya, E., Erdogan, O., Kufrevioglu, O.I., Ekinci, D., 2011. Purification and characterization of carbonic anhydrase from the teleost fish dicentrarchus labrax (european seabass) liver and toxicological effects of metals on enzyme activity. Environmental Toxicology and Pharmacology. 32, 69-74.
  21. Ozturk Sarikaya, S.B., Topal, F., Senturk, M., Gulcin, I., Supuran, C.T. 2011. In vitro inhibition of some phenolic compounds on some -carbonic anhydrase isozymes. Bioorganic & Medicinal Chemistry Letters. 21, 4259-4262.
  22. Cakmak, R., Durdagi, S., Ekinci, D., Senturk, M., Topal, G. 2011. Design, synthesis and biological evaluation of novel nitroaromatic compounds as potent glutathione reductase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21, 5398-5402.
  23. Senturk, M., Ekinci, D., Alici, H.A., Beydemir, S., 2011. Paraoxonase-1, an organophosphate detoxifier and cardioprotective enzyme, is inhibited by anesthetics: an in vitro and in vivo insight. Pesticide Biochemistry and Physiology. 101, 206-211.
  24. Ekinci, D., Senturk, M., Kufrevioglu, O.I. 2011. Salicylic acid derivatives: synthesis, features and usage as therapeutic tools. Expert Opinion On Therapeutic Patents. 21, 1831-1841.
  25. Cavdar, H., Ekinci, D., Talaz, O., Saracoglu, N., Senturk, M., Supuran, C.T. 2012. -Carbonic anhydrases are sulfatases with cyclic diol monosulfate esters. Journal of Enzyme Inhibition and Medicinal Chemistry. 27, 148-154.
  26. Senturk, M., Ekinci, D., Goksu, S., Supuran, C.T. 2012. Effects of dopaminergic compounds on carbonic anhydrase isozymes I, II, and VI. Journal of Enzyme Inhibition and Medicinal Chemistry, doi: 10.3109/14756366.2011.591290.
  27. Sahin, A., Senturk, M., Akkemik, E., Ciftci, M., 2012. The effects of chemical and radioactive properties of Tl-201 on human erythrocyte glutathione reductase activity. Nuclear Medicine and Biology. 39, 161-165.
  28. Ekinci, D., Senturk, M. 2012. Assesment of metal inhibition of antioxidant enzyme glutathione reductase from rainbow trout liver. Journal of Enzyme Inhibition and Medicinal Chemistry, doi: 10.3109/14756366.2011.615745.
  29. Balaydin, H.T., Senturk, M., Menzek, A. 2012. Synthesis and carbonic anhydrase inhibitory properties of novel cyclohexanonyl bromophenol derivatives. Bioorganic & Medicinal Chemistry Letters. 22, 1352-1357.
  30. Ekinci, D., Kurbanoglu, N.I., Salamci, E.,Senturk, M., Supuran, C.T. 2012.In vitroinhibition of some benzenesulfonamides and cyclitols on some carbonic anhydrase isozymes. Journal of Enzyme Inhibition and Medicinal Chemistry, doi: 10.3109/14756366.2011.621122.
  31. Ekinci, D., Cavdar, H., Durdagi, S., Talaz, O.,Senturk, M., Supuran, C.T. 2012. Structure-activity relationships for the interaction of 5,10-dihydroindeno[1,2-b]indole derivatives with human and bovine carbonic anhydrase isoforms I, II, III, IV and VI. European Journal of Medicinal Chemistry. 49, 68-73.
  32. Mercan, L., Okumus, A.,Senturk, M., Ekinci, D. 2012.In vitroenzymatic response of Turkish native chicken “Gerze” to heavy metal exposure. Journal of Enzyme Inhibition and Medicinal Chemistry, doi: 10.3109/14756366.2011.627509.


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