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Biography
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Dr. Jenny Wong

Illawarra Health and Medical Research Institute and the School of Biological Sciences

University of Wollongong, Australia

Molecular Biologist and Biochemist


Email: jwong@uow.edu.au


Qualifications

2007 Ph.D., School of Biotechnology and Biomolecular Sciences, University of New South Wales, Australia

2004 B.Sc., School of Biotechnology and Biomolecular Sciences, University of New South Wales,Australia


Publications (selected)

  1. Wong J, Duncan C, Beveridge N, Webster MJ, Cairns M, and Weickert CS (2012). Expression of NPAS3 in the human cortex and evidence of its post-transcriptional regulation by miR-17 during development, with implications for schizophrenia. Schizophr Bull. Epub ahead of print (6th Jan 2012).
  2. Bhatia S, Knoch B, Wong J, Kim WS, Else PL, Oakley AJ, and Garner B. (2011). Selective Reduction of Hydroperoxyeicosatetraenoic Acids to their Hyrdoxy Derivatives. Biochem J. Epub ahead of print (12th Dec 2011).
  3. Wong J, Woon HG and Weickert CS (2011). Interaction between estrogen receptor alpha and TrkB suggests convergence in gene susceptibility pathways in schizophrenia. Mol Cell Neurosci 46:67-78.
  4. Wong J, Hyde TM, Cassano HL, Deep-Soboslay A, Kleinman JE and Weickert CS (2010). Promoter Specific Alterations of BDNF mRNA in Schizophrenia. Neuroscience.169:1071-1084.
  5. Luberg K, Wong J, Weickert CS, Timmusk T (2010). Human TrkB gene: novel alternative transcripts, protein isoforms and expression pattern in the prefrontal cerebral cortex during postnatal development. J Neurochem 113:952-964.
  6. Wong J and Weickert CS (2009). Transcriptional interaction of an estrogen receptor splice variant and ErbB4 suggest convergence in gene susceptibility pathways in schizophrenia. J Biol Chem 284:18824-18832.
  7. Kim WS, Wong J, Weickert CS and Garner B (2009). Age-related regulation of apolipoprotein-D expression in human prefrontal cortex. J Neurochem 109:1053-1066.
  8. Wong J, Webster MJ, Cassano H and Weickert CS (2009). Changes in alternate brain-derived neurotrophic factor transcript expression in the developing human prefrontal cortex. Eur J Neurosci 29:1311-1322.
  9. Wong J, Quinn CM, Gelissen IC, and Brown AJ (2008). Endogenous 24(S),25- epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis. J Biol Chem 283:700-707.
  10. Yan D, Mäyränpää MI, Wong J, Perttilä J, Lehto M, Jauhiainen M, Kovanen PT, Ehnholm C, Brown AJ and Olkkonen VM (2008). The endoplasmic reticulum oxysterol-binding protein ORP8 suppresses cholesterol efflux from macrophages. J Biol Chem 283:332-340.
  11. Wong J, Quinn CM, Guillemin G and Brown AJ (2007). Primary human astrocytes produce 24(S),25 epoxycholesterol with implications for brain cholesterol homeostasis. J Neurochem 103(5):1764-1773.
  12. Wong J, Quinn CM and Brown AJ (2006). SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1 by generating oxysterol ligands for LXR. Biochem J 400:485-491.
  13. Glaros EN, Kim WS, Quinn CM, Wong J, Gelissen I, Jessup W and Garner B (2005). Glycosphingolipid accumulation inhibits cholesterol efflux via the ABCA1/apolipoprotein A-I pathway: 1-phenyl-2-decanoylamino-3-morpholino-1-propanol is a novel cholesterol efflux accelerator. J Biol Chem 280:24515-24523.
  14. Quinn CM, Jessup W, Wong J, Kritharides L and Brown AJ (2005). Expression and regulation of sterol 27-hydroxylase (CYP27A1) in human macrophages: a role for RXR and PPARgamma ligands. Biochem J 385:823-830.
  15. Wong J, Quinn CM and Brown AJ (2004). Statins inhibit synthesis of an oxysterol ligand for the liver X receptor in human macrophages with consequences for cholesterol flux. Arterioscler Thromb Vasc Biol 24:2365-2371


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