Dr. Alan Dart Loon Sihoe

Dr. Alan Dart Loon Sihoe

The University of Hong KongandQueen Mary Hospital, China

Associate Professor



1992-1994 MBBChir, Cambridge University, UK

1989-1992 BA, Cambridge University(pre-clinical), UK

Publications (selected)

  1. Arifi AA, Wong RH, Sihoe AD, Manlulu AV. Double aortic arch causing tracheo-esophageal obstruction.Asian Cardiovasc Thorac Ann 2006; 14:88.
  2. Wong RH, Tse GM, Sihoe AD, Lee TW, Wan IY, Arifi AA, Yim AP. Lung adenocarcinoma with solitary metastasis to nasopharynx: a long-term survivor after radiotherapy. Chest 2005; 128:475S.
  3. Sihoe ADL, Lee TW, Wan IYP, Thung KH, Yim APC.The use of gabapentin for post-operative and post-traumatic pain in thoracic surgery patients.Eur J Cardiothorac Surg 2006; 25:795-799.
  4. Garzon JC, Ng CSH, Sihoe ADL, Manlulu AV, Wong RHL, Lee TW, Yim APC.Video-assisted thoracic surgery pulmonary resection for lung cancer in patients with poor lung function.Ann ThoracSurg2006; 81:1996-2003.
  5. Wong RHL, Lee TW, Sihoe ADL, Wan IYP, Ng CSH, Chan SKC, Wong WWL, Liang YM, Yim APC.Analgesic effect of electro-acupuncture in post-thoracotomy pain: a prospective randomized trial.AnnThorac Surg 2006; 81:2031-2036.
  6. Sihoe ADL, Cheng LC, Sit AKY. Mediastinal parathyroid cyst: a rare benign cause of voice hoarseness. Chest 2006; 130:347S.
  7. Tsang FHF, Chung SS, Sihoe ADL.Video-assisted thoracic surgery for bronchopulmonary sequestration. Interactive CardioVasc Thorac Surg 2006; 5:424 – 426.
  8. Sihoe ADL, Manlulu AV, Lee TW, Thung KH, Yim APC. Pre-emptive local anesthesia for needlescopic video-assisted thoracic surgery: a randomized controlled trial. Eur J Cardiothorac Surg 2007; 31:103 - 108.
  9. Tsang FHF, Sihoe ADL, Cheng LC. Unusual retained foreign body in the lung: a tree branch. Eur J Cardiothorac Surg 2007; 31: 309 - 310.
  10. Sihoe ADL, Chan HHY. Surgical management of pulmonary emphysema: an update for primary care physicians. Hong Kong Practitioner 2007; 29:43-51.
  11. Sihoe ADL, Ng VMW, Liu RWT, Cheng LC. Pulmonary alveolar proteinosis in extremis: the case for aggressive whole lung lavage with extracorporeal membrane oxygenation support. Heart LungCirculation 2007; 17:69-72.
  12. Chan DTL, Sihoe ADL, Chan S, Tsang DSF, Fang B, Lee TW, Cheng LC.Surgery for empyema thoracis: is video-assisted thoracic surgery 'better' than thoracotomy?Ann Thorac Surg 2007; 84:225-231.
  13. Sihoe AD, Liu RW, Lee AK, Lam CW, Cheng LC. Is previous thoracic sympathectomy a risk factor for exertional heat stroke? Ann Thorac Surg 2007; 84:1025-1027.
  14. Wong MK, Wong MP, Lam DC, Sihoe A, Cheng LC, Lam B, Ip MS, Nakajima T, Yasufuku K, Lam WK, Ho JC. Endobronchial ultrasound for diagnosis of synchronous primary lung cancers.Lung Cancer2009; 63:154-157.
  15. Wong DW, Leung EL, So KK, Tam IY, Sihoe AD, Cheng LC, Ho KK, Au JS, Chung LP, Pik Wong M; University of Hong Kong Lung Cancer Study Group. The EML4-ALK fusion gene is involved in varioushistologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS. Cancer 2009; 115:1723-1733.
  16. Sihoe AD, Das SR, Ling LC, Cheng LC.Retrieval of broken paravertebral catheter by video-assisted thoracic surgery.Asian Cardiovasc Thorac Ann 2008; 16:321-323.
  17. Leung EL, Tam IY, Tin VP, Chua DT, Sihoe AD, Cheng LC, Ho JC, Chung LP, Wong MP. SRC promotes survival and invasion of lung cancers with epidermal growth factor receptor abnormalities and is apotential candidate for molecular-targeted therapy. Mol Cancer Res 2009; 7:923-932.
  18. Sihoe AD. Survival and risk factors of surgically treated mediastinal invasion T4 non-small cell lung cancer. [Invited commentary] Ann Thorac Surg 2009; 88:378-379.
  19. Chan RW, Chan MC, Wong AC, Karamanska R, Dell A, Haslam SM, Sihoe AD, Chui WH, Triana-Baltzer G, Li Q, Peiris JS, Fang F, Nicholls JM. DAS181 inhibits H5N1 influenza virus infection of humanlung tissues. Antimicrob Agents Chemother 2009; 53:3935-3941.
  20. Tam IY, Leung EL, Tin VP, Chua DT, Sihoe AD, Cheng LC, Chung LP, Wong MP. Double EGFR mutants containing rare EGFR mutant types show reduced in vitro response to gefitinib compared withcommon activating missense mutations. Mol Cancer Ther 2009; 8:2142-2151.
  21. Sihoe AD, Shiraishi Y, Yew WW. The current role of thoracic surgery in tuberculosis management. Respirology 2009; 14:954-968.
  22. Chan MC, Chan RW, Yu WC, Ho CC, Yuen KM, Fong JH, Tang LL, Lai WW, Lo AC, Chui WH, Sihoe AD, Kwong DL, Wong DS, Tsao GS, Poon LL, Guan Y, Nicholls JM, Peiris JS. Tropism and innate hostresponses of the 2009 pandemic H1N1 influenza virus in ex vivo and in vitro cultures of human conjunctiva and respiratory tract. Am J Pathol 2010; 176:1828-1840.
  23. Sit AK, Sihoe AD, Suen WS, Cheng LC.Positron-emission tomography for lung cancer in a tuberculosis-endemic region. Asian Cardiovasc Thorac Ann 2010; 18:33-38.
  24. Lee SM, Chan RW, Gardy JL, Lo CK, Sihoe AD, Kang SS, Cheung TK, Guan YI, Chan MC, Hancock RE, Peiris MJ. Systems-level comparison of host responses induced by pandemic and seasonalinfluenza A H1N1 viruses in primary human type I-like alveolar epithelial cells in vitro. Respir Res 2010; 11:147.
  25. Leung EL, Fiscus RR, Tung JW, Tin VP, Cheng LC, Sihoe AD, Fink LM, Ma Y, Wong MP. Non-small cell lung cancer cells expressing CD44 are enriched for stem cell-like properties. PLoS One 2010;5:e14062.
  26. Wong DW, Leung EL, Wong SK, Tin VP, Sihoe AD, Cheng LC, Au JS, Chung LP, Wong MP. A novel KIF5B-ALK variant in nonsmall cell lung cancer. Cancer 2011; 117:2709-2718.

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