Prof. Yu-Wen Tien

National Taiwan University, Chinese Taipei



2001 PhD in Medical Science Graduate Institute of Clinical Medicine, National Taiwan University

1985 M.D. in Koashung Medical College

Publications (Selected)

  1. Yu-Wen Tien, King-Jen Chang*, Yung-Ming Jeng, Po-Huang Lee, Ming-Shi Wu, Jaw-Town Lin, Su-Ming Hsu. Tumor Angiogenesis and Its Possible Role in Intravasation of Colorectal Epithelial. Clin Cancer Res 2001; 7:1627-1632.
  2. Jin-De Chen, Ming-Shiang Wu, Yu-Wen Tien, Kuang-Ting Kuo, Ming-Chu Chang, Jaw-Town Lin. Acinar cell carcinoma with hypervascularity. J Gastroenterol & Hepatol. 2001; 16: 107-11.
  3. Ming-Chu Chang, Yu-Ting Chang, Ming-Shiang Wu, Chia-Tung Shun, Yu-Wen Tien, Jaw-Town Lin. K-ras Mutation at Codon 12 in Stage I Pancreatic Adenocarcinoma: Analysis by Laser Capture Microdissection and Direct Sequencing. J Formos Med Assoc 2001; 100: 352-354.
  4. Yu-Wen Tien, Po-Huang Lee, Shih-Ming Wang, Su-Ming Hsu, King-Jen Chang*. Simultaneous Detection of Colonic Epithelial Cells in Portal Venous and Peripheral Blood. Dis Colon & Rectum 2002; 45: 23-29.
  5. Yu-Wen Tien*, King-Jen Chang. Diffuse pancreatic islet cell disease with hyperinsulinism in adults: problems in recognition and management. Chinese Med. J.2002; 65: 91-92.
  6. Yu-Wen Tien, Po-Huang Lee*, Rey-Heng Hu, Su-Ming Hsu, King-Jen Chang. The Role of Gelatinase in hepatic metastasis of colorectal cancer. Clin Cancer Res 2003; 9: 4891-6.
  7. Yu-Wen Tien*, Yung-Ming Jeng, Rey-Heng Hu, Po-Huang Lee, King-Jen Chang. Intravasation-Reltated metastatic factors in colorectal cancer. Tumor Biology 2004; 25:48-55.
  8. Yu-Wen Tien*, Hsien-Li Kao, and Hsiu-Po Wang. Celiac Artery Stenting: A New Strategy for Patients with Pancreaticoduodenal Artery. J. Gastroenterol. 2004; 39: 81-85.
  9. Chin-Sheng Hung, Peter Lin, Yu-Wen Tien*, Po-Huang Lee. Duodenum-Preserving pancreatic head resection: Preliminary report on indications and techniques Formos J. Surg. 2004; 37:254-260.
  10. Yu-Min Huang, Haw-Tzong Chen, Yao-Jen Chang, Yu-Wen Tien*. Huge Periampullary Tumors Simulating Hepatic Hilar Tumors---A Report of Three Cases. Tzu-Chi Med. J 2004; 16: 193-6.
  11. Yu-Wen Tien*, Kong-Han Ser, , Rey-Heng Hu , Chih-Yuan Lee , Yung-Ming Jeng , Po-Huang Lee. Solid Pseudopapillary Neoplasms of the Pancreas: is there a pathologic basis for the gender difference in incidence. Surgery 2005; 137: 591-6.
  12. Yu-Wen Tien*, Po-Huang, Chin-Yao Yang, Ming-Chih Ho, Chen-Feng Chiu. Risk factors of massive bleeding after pancreatic leak following oancreaticoduodenectomy. J of American College Surgeon 2005, 201:554-9.
  13. Ming-Chu Chang, Yu-Ting Chang, Yu-Wen Tien, Chia-Tung Sun, Ming-Shiang Wu, Jaw-Town Lin. Distinct chromosomal aberrations of ampulla of vater and pancreatic head cancers detected by laser capture microdissection and comparative genomic hybridization. Oncology Reports 2005; 14; 867-72
  14. Yu-Wen Tien*, King-Jen Chang, Yen-Feng Chiu, Kai-Wen Huang, Po-Huang Lee. Comparison of Angiogenic Factor Levels in Tumor Drainage and Peripheral Venous Blood from Colorectal Cancer Patients. Ann Surg Oncol, 2006; 13: 1357-63.
  15. Lee TC. Liu KL. Tien YW. Shun CT. Wang HP. Subserosal bullae in pneumatosis intestinalis. Surgery 2006; 139(6):851-3.
  16. Lee TC. Liu KL. Lin JT. Tien YW. Mao TL. Wang HP. An unusual cause of pancreatitis--patient with dominant dorsal pancreatic duct syndrome and intraductal papillary mucinous neoplasm (IPMN) in the ventral pancreatic duct. Gut 2006;55(2):164, 171.
  17. Ming-Chug Chang , Yu-Ting Chang, Chia-Tung Sun, Yen-Feng Chiu, Jaw-Town Lin, and Yu-Wen Tien*. Differential expressions of cyclin D1 associated with better prognosis of cancers of ampulla of Vater. World J Surg 2007; 30: 1-8.
  18. Chang MC. Chang YT. Tien YW. Liang PC. Wei SC. Wong JM.. Association of tumour necrosis factor alpha promoter haplotype with chronic pancreatitis. Gut 2006; 55(11):1674-6.
  19. Ji-Shiang Hung, Ming-Chu Chang, Po-Huang Lee, Yu-Wen Tien*. Is surgery indicated for patients with symptomatic nonfunctioning pancreatic neuroendocrine tumor and unresectable hepatic metastases? World J Surg 2007; 30: 1-8.
  20. Ji-Shiang Hung, Ching-Yao Yang, Rey-Heng Hu, Po-Huang Lee, Yu-Wen Tien*. Surgical treatment of pancreatic serous cystadenoma- Aggressive for operations but limited resections. Pancreas 2007, 35:358-360.
  21. Chang MC. Chang YT. Tien YW. Liang PC. Jan IS. Wei SC. Wong JM. T-cell regulatory gene CTLA-4 polymorphism/haplotype association with autoimmune pancreatitis. Clinic Chem 2007; 53(9):1700-5.
  22. Chang MC. Chang YT. Su TC. Yang WS. Chen CL. Tien YW. Liang PC. Wei SC. Wong JM. Adiponectin as a potential differential marker to distinguish pancreatic cancer and chronic pancreatitis. Pancreas 2007; 35(1):16-21.
  23. Chang MC. Chang YT. Wei SC. Tien YW. Liang PC. Jan IS. Su YN. Wong JM. Spectrum of mutations and variants/haplotypes of CFTR and genotype-phenotype correlation in idiopathic chronic pancreatitis and controls in Chinese by complete analysis. Clinical Genetics. 2007; 71(6):530-9.
  24. Yu-Wen Tien*, Rey-Heng Hu, Ji-Shiang Hung, Hsui-Po Wang, Po-Huang Lee. Noninvasive pancreatic cystic neoplasms can be safely and effectively treated by limited pancreatectomy. Ann Surg Oncol 2008; 15:193-198.
  25. Yu-Wen Tien*, Yao-Ming Wu, Kao-Lang Liu, Cheng-Maw Ho, Po-Huang Lee. Angiography is indicated for every sentinel Bleed. Ann Surg Oncol 2008; 15: 1855-1861.
  26. Chang YT, Chang MC, Wei SC, Tien YW, Hsu C, Liang PC, Tsao PN, Jan IS. Wong JM. Serum vascular endothelial growth factor/soluble vascular endothelial growth factor receptor 1 ratio is an independent prognostic marker in pancreatic cancer. Pancreas 2008; 37:145-150.
  27. Liu KL. Teng YC. Tien YW. Lin JT. Elevated alpha-fetoprotein and a pancreatic tumour. Gut 2008; 57:434.
  28. Chen BB, Tien YW, Lin JT, Liu KL. Image of the month. Ectopic spleen in the pancreatic tail. Arch Surg 2008; 143: 205-206.
  29. Yu-Wen Tien*, Ching-Yao Yang, Yao-Ming Wu, Rey-Heng Hu, Po-Huang Lee. Enteral Nutrition and Biliopancreatic Diversion Effectively Minimize Impacts of Gastroparesis after Pancreaticoduodenectomy. J Gastrointest Surg 2009; 13: 929-937.
  30. Yu-Wen Tien*, Yao-Ming Wu1, Wei-Chou Lin, Hsuan –Shu Lee, Po-Huang Lee. Pancreatic carcinoma cells stimulate proliferation and matrix synthesis of hepatic stellate cells. J Hepatology 200; 51: 307-14.
  31. Yu-Wen Tien*, Chi-Chuan Yeh, Shi-Po Wang, Rey-Heng Hu, Po-Huang Lee. Is Blind Pancreaticoduodenectomy Justified for Patients With Ampullary Neoplsms? J Gastrointest Surg 2009; 13: 929-937
  32. Yu-Wen Tien*, Chih-Yuan Lee, Chun-Chieh Huang Rey-Heng Hu, Po-Huang Lee. Surgery for gastrointestinal stroma tumor of the duodenum. Ann Surg Oncol 2010; 17: 109-114.
  33. Yu-Wen Tien*, Kao-Lang Liu, Rey-Heng Hu, Hsiu-Po Wang, King-Jen Chang, Po-Huang Lee. Risk of varices bleeding after spleen-preserving distal pancreatectomy with excision of splenic vessels. Ann Surg Oncol 2010, in press.
  34. Chi-Chuan Yeh, Yung-Ming Jeng, Cheng-Maw Ho, Rey-Heng Hu, Hsiu-Pi Chang, Yu-Wen Tien*. Survival after pancreaticoduopdenectomy is not affected by age. World J Surg 2010, 34:2945-2952.
  35. Jin-Ming Wu, Meng-Kun Tsai, Rey-Heng Hu, Kin-Jen Chang, Po-Huang Lee, Yu-Wen Tien*. Reflux Esophagitis and Marginal Ulcer after Pancreaticoduodenectomy (corresponding author). J Gastrointest Surg 2011, in press.