Dr. Yoshihide
Fujigaki
Teikyo
University, Japan
Professor
Email: fujigakiyoshihide@gmail.com
Qualifications
1991 Ph.D., Hamamatsu University, Japan
1984 M.Sc., Hamamatsu University, Japan
Publications
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Sun Y, Fujigaki Y, Sakakima M, Fujikura T,
Togawa A, Huang Y, Hishida A: Acquired resistance to rechallenge injury in rats
that recovered from mild renal damage induced by uranyl acetate: accelerated
proliferation and hepatocyte growth factor/c-Met axis. Clin Exp Nephrol.
15:666-75, 2011.
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Sakao Y, Kato A, Tsuji T, Yasuda H, Togawa A,
Fujigaki Y, Kahyo T, Setou M, Hishida A: Cisplatin induces Sirt1 in association
with histone deacetylation and increased Werner syndrome protein in the kidney.
Clin Exp Nephrol. 15:363-72, 2011.
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Yasuda H, Kato A, Fujigaki Y, Hishida A:
Incidence and clinical outcomes of acute kidney injury requiring renal
replacement therapy in Japan. 2010. Ther Apher Dial 6:541-546.2010.
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Togawa A, Sfakianos J, Ishibe S, Suzuki S,
Fujigaki Y, Kitagawa M, Mellman I, Cantley LG: Hepatocyte Growth Factor
stimulated cell scattering requires ERK and Cdc42-dependent tight junction
disassembly. Biochem Biophys Res Commun. 400:271-277,2010.
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Fujigaki Y, Sun Y, Fujikura T, Sakao Y,
Togawa A, Suzuki H, Yasuda H, Hishida A: Immunohistochemical study of heat
shock protein 27 with respect to survival and regeneration of proximal tubular
cells after uranyl acetate-induced acute tubular injury in rats. Ren Fail
32:119-125, 2010.
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Fukasawa H, Yamamoto T, Fujigaki Y, Misaki T,
Ohashi N, Uakayama T, Mugiya S, Oda T, Uchida C, Kitagawa K, Hattori T, Suzuki
S, Hayashi H, Ozono S, Kitagawa M, Hishida A: Reduction of transforming
growth factor-ß type II receptor is caused by the enhanced ubiquitin-dependent
degradation in human renal cell carcinoma. Int J Cancer. 127:1517-1525, 2010.
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Sun Y, Fujigaki Y, Sakakima M, Hishida A:
Acquired resistance to rechallenge injury in rats recovered from subclinical
renal damage with uranyl acetate - Importance of proliferative activity of
tubular cells. Toxicol Appl Pharmacol. 243:104-110, 2010.
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Misaki T, Yamamoto T, Suzuki S, Fukasawa H,
Togawa A, Ohashi N, Suzuki H, Fujigaki Y, Oda T, Uchida C, Kitagawa K, Hattori
T, Kitagawa M, Hishida A: Decrease in tumor necrosis factor-alpha
receptor-associated death domain results from ubiquitin-dependent degradation
in obstructive renal injury in rats. Am J Pathol 175:74-83, 2009.
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Ikegaya N, Yoshida T, Kohsaka T, Suzuki A,
Kobayashi N, Yamamoto T, Fujigaki Y, Hishida A, Kumagai H: Effects of relaxin
on development of mesangial proliferative nephritis. Ann N Y Acad Sci
1160:300-303, 2009.
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Fujigaki Y, Sakakima M, Sun Y, Fujikura T,
Tsuji T, Yasuda H, Hishida A: Cell division and phenotypic regression of
proximal tubular cells in response to uranyl acetate insult in rats. Nephrol
Dial Transplant 24;2686-2692, 2009.
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Tsuji T, Kato A, Yasuda H, Miyaji T, Luo J,
Sakao Y, Ito H, Fujigaki Y, Hishida A: The dimethylthiourea-induced attenuation
of cisplatin nephrotoxicity is associated with the augmented induction of heat
shock proteins. Toxicol Appl Pharmacol 234:202-208, 2009.
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Joh K, Taguchi T, Shigematsu H, Kobayashi Y,
Sato H, Nishi S, Katafuchi R, Nomura S, Fujigaki Y, Utsunomiya Y, Sugiyama H,
Saito T, Makino H: Proposal of podocytic infolding glomerulopathy as a new
disease entity: a review of 25 cases from nationwide research in Japan. Clin
Exp Nephrol 12:421-431, 2008.
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Fujigaki Y, Muranaka Y,
Sakakima M, Ohta I, Sakao Y,
Fujikura T, Sun Y, Katafuchi R,
Joh K, Hishida A: Analysis of intra-GBM
microstructures in a SLE case with glomerulopathy associated with podocytic
infolding. Clin Exp Nephrol 12:509-512, 2008.
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Ohashi N, Yamamoto T, Huang Y, Misaki T,
Fukasawa H, Suzuki H, Togawa A, Suzuki S, Fujigaki Y, Nakagawa T, Nakamura Y,
Suzuki F, Kitagawa M, Hishida A: Intrarenal RAS activity and urinary
angiotensinogen excretion in anti-thymocyte serum nephritis rats. Am J Physiol
Renal Physiol 295:F1512-1518, 2008.
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Sakakima M, Fujigaki Y, Yamamoto T, Hishida
A: A distinct population of tubular cells in the distal S3 segment contributes
to S3 segment regeneration in rats following acute renal failure induced by
uranyl acetate. Nephron Exp Nephrol 109:e57-70, 2008.
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Luo J, Tsuji T, Yasuda H, Sun Y, Fujigaki Y,
Hishida A: The molecular mechanisms of the attenuation of cisplatin-induced
acute renal failure by N-acetylcysteine in rats. Nephrol Dial Transplant
23:2198-205, 2008.
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Ohashi N, Kato A, Misaki T, Sakakima M,
Fujigaki Y, Yamamoto T, Hishida A: Association of serum adiponectin levels with
all-cause mortality in hemodialysis patients. Intern Med 47:485-491, 2008.
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Fujigaki Y, Sakakima M, Sun Y, Goto T, Ohashi
N, Fukasawa H, Tsuji T, Yamamoto T, Hishida A: Immunohistochemical study on
caveolin-1a regenerating process of tubular cells in gentamicin-induced acute
tubular injury in rats. Virchows Arch 450:671-681, 2007.
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Yamamoto T, Nakagawa T, Suzuki H, Ohashi N,
Fukasawa H, Fujigaki Y, Kato A, Nakamura Y, Suzuki F, Hishida A: Urinary
Angiotensinogen as a Marker of Intrarenal Angiotensin II Activity Associated
with Deterioration of Renal Function in Patients with Chronic Kidney Disease.
J Am Soc Nephrol 18:1558-1565, 2007.
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