Dr. Zhe Zhang

Dr. Zhe Zhang

Zhejiang University, China



2001  Ph.D., Chinese Academy of Sciences, China

1996  B.Sc., Shandong University, China

Publications (selected)

  1. Xuai Lin, Aihua Sun, Ping Ruan, Zhe Zhang, Jie Yan. Characterization of Conserved Combined T and B Cell Epitopes in Leptospira interrogans Major Outer Membrane Proteins OmpL1 and LipL41. BMC Microbiol. 2011, Jan 26; 11(1): 21.
  2. Zhe Zhang, Thomas B. Clarke, and Jeffrey N. Weiser. Cellular effectors mediating Th17-dependent clearance of pneumococcal colonization in mice. J Clin Invest, 2009, 119: 1899-1909. *Science News (ScienceDaily, June 17, 2009): Clearing pneumococcal bacteria from the upper airways.
  3. Zhe Zhang, William Reenstra, Daniel J. Weiner, Jean-Pierre Louboutin, and James M. Wilson. The p38 mitogen-activated protein kinase signaling pathway is coupled to Toll-like receptor 5 to mediate gene regulation in response to Pseudomonas aeruginosa infection in human airway epithelial cells. Infect Immun, 2007, 75: 5985-5992.
  4. Zhe Zhang, Jean-Pierre Louboutin, Daniel J. Weiner, Joanna B. Goldberg, and James M. Wilson. Human airway epithelial cells sense Pseudomonas aeruginosa infection via recognition of flagellin by Toll-like receptor 5. Infect Immun, 2005, 73: 7151-7160.
  5. Wen-Bo Zhang, Zhe Zhang (co-first author), Yan-Xiang Ni, Ya-Lan Wu and Gang Pei. A novel function of Goα: mediation of extracellular signal-regulated kinase activation by opioid receptors in neural cells. J Neurochem, 2003, 86: 1213-1222.
  6. Xiaorong Wang, Zhe Zhang, Jean-Pierre Louboutin, Christian Moser, Daniel J. Weiner, and James M. Wilson. Airway epithelia regulate expression of human β-defensin 2 through toll-like receptor 2. FASEB J, 2003, 17: 1727-1729.
  7. Zhu-Bin Lei, Zhe Zhang, Qing Jing, Yong-Wen Qin, Gang Pei, Beng-Zhen Cao, Xiao-Yan Li. OxLDL upregulates CXCR2 expression in monocytes via scavenger receptors and activation of p38 mitogen-activated protein kinase. Cardiovascular Research, 2002, 53: 524–532.
  8. Zhe Zhang, Shun-Mei Xin, Guo-Xiang Wu, Wen-Bo Zhang, Lan Ma, and Gang Pei. Endogenous δ-opioid and ORL1 receptors couple to NG108-15 cells and this is regulated by protein kinase A and protein kinase C. J Neurochem, 1999, 73: 1502-1509.
  9. Li-Guang Lou, Zhe Zhang (co-first author), Lan Ma, and Gang Pei. Nociceptin/Orphanin FQ activates mitogen-activated protein kinase in Chinese hamster ovary cells expressing opioid receptor-like receptor. J Neurochem, 1998, 70: 1316-1322.
  10. Guo-huang Fan, Jing Zhao, Ya-Lan Wu, Li-Guang Lou, Zhe Zhang, Qing Jing, Lan Ma, and Gang Pei. N-methyl-D-aspartate attenuates opioid receptor-mediated G protein activation and this process involves protein kinase C. Molecular Pharmacology, 1998, 53: 684–690.
  11. Zhi-Jie Cheng, Guo-Huang Fan, Jian Zhao, Zhe Zhang, Ya-Lan Wu, Li-Zhen Jiang, Ye Zhu, Gang Pei, and Lan Ma. Endogenous opioid receptor-like receptor in human neuroblastoma SK-N-SH cells: activation inhibitory G protein and homologous desensitization. NeuroReport, 1997, 8: 1913-1918.