Prof. Reza Hakkak

Prof. Reza Hakkak

University of Arkansas for Medical Sciences, USA




1986  Ph.D., University of Arkansas, USA

1981  M.S., Tarleton State University, USA


Publications (Selected)

  1. Hakkak R, Shaaf S, Jo C, McLeod S and Korourian S. Effects of soy vs. casein proteindiet and obesity on DMBA-induced mammary tumor development. Oncology Letters 2: 29-36, 2011.
  2. Hakkak R, Shaaf S, Jo C, McLeod S, Korourian S. Dehydroepiandrosterone intake protects against 7,12-dimethylbenz(a)anthracene-induced mammary tumor development in the obese Zucker rat model. Oncology Reports 24: 57-362, 2010.
  3. Chowdhury P, Scott J, Holley A and Hakkak R. Obesity and laboratory diets affects tissue Malondialdehyde (MDA) levels in obese rats. J American Institute of Physics Proc. 1229, 54, 2010.
  4. Enderlin C, Coleman A, Stewart CB and Hakkak R. Dietary soy intake and breast cancer. Oncology Nursing Forum. 36:531-9, 2009.
  5. Whitehead T, Holley AW, Kieber-Emmons T, Korourian S, Shaaf S and Hakkak R. 1H nuclear magnetic resonance metabolomic analysis of mammary tumors from lean and obese Zucker rats exposed to 7,12-dimethylbenz[a]anthracene (DMBA). Int. J. Mol. Medicine, 20:573-80, 2007.
  6. Hakkak R, MacLeod S, Shaaf S, Holley AW, Simpson P, Fuchs G, Jo CH, Kieber-Emmons T, Korourian S. Obesity Increases the Incidence of 7,12-dimethylbenz(a)anthracene-Induced Mammary Tumors in Ovariectomized Zucker Rat. International Journal of Oncology, 30:557-563, 2007.
  7. Hakkak R, Holley AW, MacLeod S, Simpson P, Fuchs G, Jo CH, Kieber-Emmons T, Korourian S. Obesity Promotes 7,12-dimethylbenz(a)anthracene-Induced Mammary Tumor Development in Female Zucker Rats. Breast Cancer Research, 7:R627-R633, 2005. (According to Breast Cancer Research, this article was accessed 4,205 times as of 1/20/2010.)
  8. Ronis MJ, Hakkak R, Korourian S, Albano E, Yoon S, Ingelman-Sundberg M, Lindros KO, Badger TM. Alcoholic liver disease in rats fed ethanol as part of oral or intragastric low-carbohydrate liquid diets. Exp Biol Med. 229:351-60, 2004.
  9. Ronis MJ, Korourian S, Zipperman M, Hakkak R, Badger TM. Dietary saturated fat reduces alcoholic hepatotoxicity in rats by altering Fatty Acid metabolism and membrane composition. J. Nutr. 134:904-12, 2004.
  10. Rowlands, JC, Hakkak R, Ronis MJJ, and Badger TM. Altered mammary gland differentiation and progesterone receptor expression in rats fed soy protein and whey proteins. Toxicological Sciences 70; 40-45, 2002.
  11. Rowlands C, Hakkak R, Ronis MJJ, and Badger TM. Soy and whey proteins down-regulate DMBA-induced liver and mammary gland CYP1A, expression in female rats. J. Nutr. 131:3281-3287, 2001.
  12. Hakkak R, Korourian S, Ronis M, Johnston J, and Badger TM. Dietary whey protein protects against AOM- induced colon cancer in male rats. Cancer Epidemiology Biomarkers & Prevention. 10: 555-558, 2001.
  13. Hakkak R, Korourian S, Ronis M, Johnston J, and Badger TM. Soy protein isolate consumption protects against azoxymethane-induced colon tumors in male rats. Cancer Letters 106: 27-32, 2001.
  14. Hakkak R, Korourian S, Shelnutt S, Lensing S, Ronis MJJ, and Badger TM. Diet containing whey protein or soy protein isolate protect against DMBA-induced breast cancer in rats. Cancer Epidemiology Biomarkers & Prevention. 2000, 9; 111-117.
  15. Korourian S, Hakkak R,Shelnutt S, Ronis MJ, Waldron JA, and Badger TM. Diet and risk of ethanol-induced hepatotoxicity: carbohydrate-fat relationships in rats. Toxicological Sciences. 1999; 47:110-117.
  16. Hakkak R,Korourian S, Ronis MJJ, and Badger TM. Effects of diet and chronic ethanol treatment on azoxymethane-induced liver and gastrointestinal neoplasm of male rats. Cancer Letters 1996; 107:257-264.
  17. Hakkak R,Korourian S, Ronis MJ, Ingelman-Sundberg M, and Badger TM. Effects of diet and ethanol treatment on expression of cytochrome P450 isozymes CYP 2E1 and CYP 2C7 in the colon of male rats. Biochemical Pharmacology 1996; 51:61-69.
  18. Hakkak R, Ronis MJ, and Badger TM. Effects of enteral nutrition and ethanol on cytochrome P450 distribution in small intestine of male rats. Gastroenterology 1993; 104:1611-1618.