Prof. Zheng Dong

Medical college of Georgia

Georgia Health Sciences University, USA


Medical Research/Nephrology

Charlie Norwood VA Medical Center, USA



Publications (selected)

  1. Soodvilai S, Jia Z, Wang MH, Dong Z, Yang T.mPGES-1 Deletion Impairs Diuretic Response to Acute Water Loading.American Journal of Physiology (renal) 296(5):F1129-35. 2009.
  2. Su S, Li Y, Luo Y, Sheng Y, Padia RN, Pan ZK, Dong Z, Huang S. Proteinase-Activated Receptor 2 expression in breast cancer and its role in breast cancer cell migration. Oncogene 28: 3047-3057, 2009.
  3. Chen H, Zhu G, Li Y, Padia RN, Dong Z, Pan ZK, Liu K, Huang S. Extracellular Signal-Regulated Kinase Signaling Pathway Regulates Breast Cancer Cell Migration by Maintaining slug Expression. Cancer Research 69(24):9228-35, 2009.
  4. Zhou L, Seo K, Pacholczyk R, He H, Meng M, Xu J, Li L, She J, Dong Z, Mi Q. Tie2cre-induced inactivation of miRNA-processing enzyme Dicer disrupts invariant NKT cell development. Proceedings of National Academy of Sciences (USA)106: 10266–10271, 2009.
  5. Pabla N, Murphy R, Liu K, Dong Z. The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity. American Journal of Physiology (renal) 296(3):F505-11, 2009.
  6. Jiang M, Wang C, Huang S, Yang T, Dong Z. Cisplatin-induced apoptosis in p53-deficient renal cells via the intrinsic mitochondrial pathway. American Journal of Physiology (renal) 296(5):F983-93, 2009.
  7. Brooks C, Wei Q, Cho S, Dong Z. Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. Journal of Clinical Investigation 119(5): 1275-85, 2009.
  8. Li Y, Zhang M, Chen H, Dong Z, Ganapathy V, Thangaraju M, Huang S. Rotio of miR-196 to HOXC8 mRNA correlates to breast cancer cell migration and metastasis. Cancer Research 70(20):7894-904, 2010.
  9. Mi QS, He HZ, Dong Z, Isales C, Zhou L.microRNA deficiency in pancreatic islet cells exacerbates streptozotocin-induced murine autoimmune diabetes. Cell Cycle 9(15):3127-9. 2010.
  10. Zhang J, Dong Z, Chu L. Hydrogen Sulfide Induces Apoptosis in Human Periodontium Cells. Journal of Periodontal Research 45: 71–78, 2010.
  11. Xu M, Bower K, Chen G, Shi X, Dong Z, Ke K, Luo J. Ethanol Enhances the Interaction of Breast Cancer Cells Over-expressing ErbB2 with Fibronectin. Alcoholism: Clinical and Experimental Research 34(5):751-60, 2010.
  12. Kaddour-Djebbar I, Choudhary V, Brooks C, Ghazaly T, Lakshmikanthan V, Dong Z, Kumar MV. Specific mitochondrial calcium overload induces mitochondrial fission in prostate cancer cells. International Journal of Oncology 36(6):1437-44, 2010.
  13. Seo K, Zhou L, Meng D, Xu J, Dong Z, Mi Q. Loss of microRNAs in thymus perturbs invariant NKT cell development and function. Cellular & Molecular Immunology Nov;7(6):447-53, 2010.
  14. Dong G, Luo J, Kumar V, Dong Z. Inhibitors of histone deacetylases suppress cisplatin-induced p53 activation and apoptosis in renal tubular cells. American Journal of Physiology (Renal) 298(2):F293-300, 2010.
  15. Jiang M, Liu K, Luo J, Dong Z. Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury. American Journal of Pathology 176(3):1181-92 , 2010 (Highlighted by Kidney International 77, 563–564).
  16. Bhatt K, Zhou L, Mi Q, Huang S, She JX, Dong Z. microRNA-34a is induced via p53 during cisplatin nephrotoxicity and contributes to cell survival. Molecular Medicine 16(9-10):409-16, 2010.
  17. Wei Q, Bhatt K, He H, Mi Q, Haase VH, Dong Z. Targeted deletion of Dicer from proximal tubules protects against ischemic acute kidney injury. Journal of American Society of Nephrology 21: 756-761, 2010.
  18. Cho SG, Du Q, Huang S, Dong Z. Drp1 dephosphorylation in ATP depletion-induced mitochondrial injury and tubular cell apoptosis. American Journal of Physiology (Renal) 299 (1) F199-F206, 2010.
  19. Li X, Pabla N, Wei Q, Dong G, Messing RO, Wang C, Dong Z. PKC-δ regulates renal tubular cell apoptosis associated with proteinuria or albuminuria. Journal of American Society of Nephrology 21 1115‑1124 (Editorial Commentary by B.Lelongt. JASN 21:1063-1065).
  20. Ha Y, Dun Y, Thangaraju M, Duplantier JN, Dong Z, Liu K, Ganapathy V, Smith SB. Sigma receptor 1 modulates ER stress in retinal neurons. Investigative Ophthalmology & Visual Science 52(1):527-40, 2011.