Rupert Leong

Prof. Rupert Leong

Department of Gastroenterology and Hepatology

The University of New South Wales, Australia



2004 Fellow of the Royal Australasian College of Physicians Doctor of Medicine, Chinese University of Hong Kong, China

1994 Bachelor of Medicine. Bachelor of Surgery (UWA)

Publications (Selected)

  1. Fanning S, Kwok A, Jones B, Leong R. EUS aspiration needle size: smaller is better? Gastrointest Endosc. 2010 Oct;72(4):904-5
  2. Paramsothy S, Leong RW. Endoscopy: Fluorescein contrast in confocal laser endomicroscopy. Nat Rev Gastroenterol Hepatol. 2010 Jul;7(7):366-8
  3. Leong RW. Confocal endomicroscopy in the evaluation of celiac disease. Endoscopy. 2010 Jul;42(7):606
  4. Koo JH, Arasaratnam MM, Liu K, Redmond DM, Connor SJ, Sung JJ, Leong RW. Knowledge, perception and practices of colorectal cancer screening in an ethnically diverse population. Cancer Epidemiol. 2010 Jun 25
  5. Gearry RB, Day AS, Barclay ML, Leong RW, Sparrow MP. Azathioprine and allopurinol: A two-edged interaction. J Gastroenterol Hepatol. 2010 Apr;25(4):653-5
  6. Ooi CJ, Fock KM, Makharia GK, Goh KL, Ling KL, Hilmi I, Lim WC, Kelvin T, Gibson PR, Gearry RB, Ouyang Q, Sollano J, Manatsathit S, Rerknimitr R, Wei SC, Leung WK, de Silva HJ, Leong RW; Asia Pacific Association of Gastroenterology Working Group on Inflammatory Bowel Disease. The Asia-Pacific consensus on ulcerative colitis. J Gastroenterol Hepatol. 2010 Mar;25(3):453-68
  7. Leong RW, Kamm MA, Hu PJ, Sung JJ; Asia Pacific Inflammatory Bowel Disease Working Party. Inflammatory bowel disease in Asia. J Gastroenterol Hepatol. 2010 Mar;25(3):436-8
  8. Leong RW Environmental risk factors in inflammatory bowel disease. J Gastroenterol Hepatol. 2010 Feb;25(2):227-8
  9. Fanning SB, Chapman G, Yau Y, Leong RW. Education and imaging. Gastrointestinal: Improvement of granuloma annulare with anti-tumour necrosis factor alpha therapy for Crohn's disease. J Gastroenterol Hepatol. 2010 Jan;25(1):215
  10. Humphris J, Swartz D, Leong RW. New endoscopic technology: confocal endomicroscopy. Gastrointestinal Endoscopy Review Letters 2009 (invited)
  11. Leong RW, Chang D, Merrett ND, Biankin AV. Taking optical biopsies with confocal endomicroscopy. J Gastroenterol Hepatol. 2009 Nov;24(11):1701-3
  12. Tee HP, Swartz D, Tydd T, Leong RW. Gastrointestinal: Eosinophilic enteritis manifesting as brown-pigmented duodenal ulcers. J Gastroenterol Hepatol. 2009 Dec;24(12):1892
  13. Koo JH, Leong RW. Sex differences in epidemiological, clinical and pathological characteristics of colorectal cancer. J Gastroenterol Hepatol. 2009 Oct 27
  14. Sharifian A, Humphris J, Leong RW, Jones DB. Education and imaging. Gastrointestinal: Mycobacterium genavense enteritis in an immunosuppressed patient. J Gastroenterol Hepatol 2009;24:1474
  15. Paramsothy S, Papdopoulos G, Mollison LC, Leong RW. Resumption of oral intake following percutaneous endoscopic gastrostomy. J Gastroenterol Hepatol 2009; 24(6):1095-7
  16. Chang DK, Nguyen NQ, Merrett ND, Dixson H, Leong RW, Biankin AV. Role of endoscopic ultrasound in pancreatic cancer. Expert Rev Gastroenterol Hepatol. 2009 Jun;3(3):293-303
  17. Leong RWL. Differences in peptic ulcer between the East and the West. Gastroenterol Clin North Am. 2009 Jun;38(2):363-79
  18. Chang DK, Johns AL, Merrett ND, Gill AJ, Colvin EK, Scarlett CJ, Nguyen NQ, Leong RWL, Cosman PH, Kelly MI, Sutherland RL, Henshall SM, Kench JG, Biankin AV on behalf of the NSW Pancreatic Cancer Network. Margin Clearance and Outcome in Resected Pancreatic Cancer. J Clin Oncol. 2009;27(17):2855-62
  19. Nguyen NQ, Biankin AV, Leong RW, Chang DK, Cosman PH, Delaney P, Kench JG, Merrett ND. Real time intraoperative confocal laser microscopy-guided surgery. Ann Surg. 2009;249(5):735-7
  20. Leong RWL, Koo JH. Colorectal cancer in inflammatory bowel disease. J Gastroenterol Hepatol. 2009 Apr;24(4):503-5
  21. Chow DK, Leong RW, Tsoi KK, Ng SS, Leung WK, Wu JC, Wong VW, Chan FK, Sung JJ. Long-term follow-up of ulcerative colitis in the Chinese population. Am J Gastroenterol. 2009 Mar;104(3):647-54
  22. Chow DK, Sung JJ, Tsoi KK, Wong VW, Wu JC, Leong RW, L Chan FK. Predictors of corticosteroid-dependent and corticosteroid-refractory inflammatory Bowel Disease: analysis of a Chinese Cohort Study. Aliment Pharmacol Ther. 2009 Apr 15;29(8):843-54. Epub 2009 Jan 20
  23. Chow DK, Sung JJ, Wu JC, Tsoi KK, Leong RW, Chan FK. Upper gastrointestinal tract phenotype of Crohn's disease is associated with early surgery and further hospitalization. Inflamm Bowel Dis 2009 Apr;15(4):551-7
  24. Leung M, Piatkov, I, Rochester C, Leong RWL. Normal Thiopurine Methyl Transferase Phenotype Testing in a Crohn´s Disease Patient with Azathioprine Induced Myelosuppression. Int Med J 2009 Feb;39(2):121-6
  25. Gill AJ, Johns AL, Eckstein R, Samra JS, Kaufman A, Chang DK, Merrett ND, Cosman PH, Smith RC, Biankin AV, Kench JG; New South Wales Pancreatic Cancer Network (NSWPCN). Synoptic reporting improves histopathological assessment of pancreatic resection specimens. Pathology. 2009 Feb;41(2):161-7
  26. Leong RWL. Continuing Medical Education Activities. Gastroenterol 2008 Dec;135(6):2141-3
  27. Leong RWL, Nguyen NQ, Meredith CG, Al-Sohaily S, Kukic D, Delaney PM, Murr ER, Yong J, Merrett ND, Biankin AV. In vivo Confocal Endomicroscopy in the Evaluation of Celiac Disease. Gastroenterol 2008 Dec;135(6):1870-6 [plus journal cover]
  28. [Article selected for Faculty of 1000 Medicine]
  29. Nguyen NQ, Leong RWL. Current application of confocal endomicroscopy in gastrointestinal disorders. J Gastroenterol Hepatol 2008;23:1483-91
  30. Chang DK, Merrett ND, Biankin AV; NSW Pancreatic Cancer Network. Improving outcomes for operable pancreatic cancer: is access to safer surgery the problem? J Gastroenterol Hepatol. 2008;23:1036-45
  31. Leong RW, Gearry RB, Sparrow MP. Thiopurine hepatotoxicity in inflammatory bowel disease: the role for adding allopurinol. Expert Opin Drug Saf. 2008;7:607-16
  32. Koo JH, Wong SKC, Kneebone A, Jalaludin B, Liu K, Arasaratnam MM, Redmond D, Connor SJ, Leong RWL. Clinical and pathologic outcomes of colorectal cancer in a multi-ethnic population. Clin Gastroenterol Hepatol 2008;6(9):1016-21
  33. Koo JH, Jalaludin B, Wong SK, Kneebone A, Connor SJ, Leong RW. Improved survival in young women with colorectal cancer. Am J Gastroenterol. 2008;103:1488-95
  34. Kwok A, Lam T, Katelaris P, Leong RW. Helicobacter pylori eradication therapy: indications, efficacy and safety. Expert Opin Drug Saf. 2008;7:271-81
  35. Al-Sohaily S, Leong RWL. The yield of ileoscopy in colonoscopy (editorial). J Gastroenterol Hepatol 2008; 23: 4-5
  36. Chow DKL, Leong RWL, Lai LH, Wong GLH, Leung WK, Chan FKL, Sung JJY. Changes in Crohn’s Disease Phenotype over time in the Chinese Population: Validation of the Montreal Classification System. Inflam Bowel Dis 2008; 14:536-41
  37. Chow DKL, Leong RWL. Tacrolimus in the treatment of inflammatory bowel disease. Expert Opin Drug Saf 2007;6(5):479-486
  38. Holthouse DJ, Chen F, Leong RW, Chleboun J, Hallam L. Aeromonas hydrophilia colitis mimicking ischaemic colitis in an elderly woman. J Gastroenterol Hepatol. 2007;22:1554-5
  39. Chin BW, Leong RW, Chong AK, Chieng YH, Meredith C. Inferior vena cava filter eroding into duodenum. Gastrointest Endosc 2006;64(5):817
  40. Leong RWL, Chan FKL. Drug-induced side effects affecting the gastrointestinal tract. Expert Opin Drug Saf 2006;5:585-92
  41. Leong RWL, Lawrance IC, Chow DKL, To KF, Lau JY, Wu J, Leung WK, Chan FKL, Sung JJY. Association of Intestinal Granulomas with Smoking, Phenotype, and Serology in Chinese Patients with Crohn’s Disease. Am J Gastroenterol 2006; 101:1024-9
  42. Chin BW, Grimm M, Connor SJ, Leong RWL. Inflammatory bowel disease. Medicine Today 2006;7:14-24 plus journal cover
  43. Lawrance IC, Hall A, Leong R, Pearce C, Murray K. A Comparative Study of Goblet Cell and Pancreatic Exocrine Autoantibodies Combined with ASCA and pANCA in Chinese and Caucasian Patients with IBD. Inflamm Bowel Dis 2005;11:890-897
  44. Hung LC, Ching JY, Sung JJ, To KF, Hui AJ, Wong VW, Leong RW, et al. Long-term Outcome of Helicobacter pylori-Negative Idiopathic Bleeding Ulcers: A Prospective Cohort Study. Gastroenterol 2005;128:1845-50
  45. Leong RWL, Lawrance IC, Ching JYL, Cheung VMY, Fung SSL, Ho JNC, Philpott J, Wallace AR, Sung JJY. Knowledge, quality of life and use of complementary and alternative medicine and therapies in inflammatory bowel disease: a comparison of Chinese and Caucasian patients. Dig Dis Sci 2004;49:1672-6
  46. Lawrance IC, Murray K, Hall A, Sung JJ, Leong RW. A prospective comparative study of ASCA and pANCA in Chinese and Caucasian IBD patients. Am J Gastroenterol 2004;99:2186-94
  47. Leong RWL, Smith DW, Garas G, Beaman JM, Mitchell AW, Heath DI, House AK, Jeffrey GP. A cost-effectiveness analysis of aciclovir or ganciclovir in cytomegalovirus universal prophylaxis in liver transplantation. Int Med J 2004;34:410-5
  48. Leong RW, Lau JY, Sung JJY. The epidemiology and phenotype of Crohn’s disease in the Chinese population. Inflam Bowel Dis 2004; 10:646-51
  49. Wu JC, Chan FK, Ching JY, Leung WK, Hui Y, Leong RW, Chung SC, Sung JJ. Effect of Helicobacter pylori eradication on treatment of gastro-oesophageal reflux disease: a double blind, placebo controlled, randomized trial. Gut 2004;53:174-9
  50. Wong VWS, Leong RW, Chan FKL. Upper gastrointestinal complications related to non-steroidal anti-inflammatory drugs – what have we achieved so far? Digest Liver Dis2004;36;1-3
  51. Leong RW, House AK, Jeffrey GP. Chylous ascites caused by portal vein thrombosis treated with octreotide. J Gastroenterol Hepatol 2003;18:1211-3
  52. Lee YT, Walmsley RS, Leong RW, Sung JJ. Dieulafoy's lesion. Gastrointest Endosc 2003;58:236-43
  53. Leong RW, Armuzzi A, Ahmad T, Wong ML, Tse P, Jewell DP, Sung JJY. NOD2/CARD15 gene polymorphisms and Crohn’s disease in the Chinese population. Aliment Pharm Ther 2003;17:1465-70
  54. Yu J, Leung WK, Ebert MPA, Leong RW, Tse CH, Chan MMW, Bai AHC, Malfertheiner P, Sung JJY. Absence of Cyclin D2 expression is associated with promoter hypermethylation in gastric cancer. Br J Cancer 2003;88:1560-5
  55. Leong RW, Lee YT. Ching JYL, Sung JJY. Quality of life in Chinese patients with inflammatory bowel disease: validation of the Chinese translation of the inflammatory bowel disease questionnaire. Aliment Pharmacol Ther 2003;17:711-8
  56. Leong RW, Lee CC, Ling TK, Leung WK, Sung JJ. Evaluation of the string test for the detection of Helicobacter pylori. World J Gastroenterol 2003; 9:309-11
  57. Sung JJY, Lee YT, Leong RW. EUS in portal hypertension. Gastrointest Endosc 2002; 56:S35-42
  58. Leung WK, Hung LCT, Kwok CKL, Leong RW, Ng ACW, Ng DKK, Sung JJY. Serial urea breath test results in patients after consumption of antibiotics for extra-gastrointestinal infections. World J Gastroenterol 2002; 8:703-6
  59. Leong RW, JJY Sung. Helicobacter and hepatobiliary diseases. Aliment Pharmacol Ther. 2002; 16;1037-45
  60. Leong RW, Chan FK, Sung JJ. Helicobacter pylori and nonsteroidal anti-inflammatory drugs. Approaching the end of the controversy in the new millennium, or room for more debate? J Gastroenterol. 2001;36:731-9
  61. Leong RW, Lee YT, Leung WK, Sung JJY. Histologic findings after cyanoacrylate inj ection. Gastrointest Endosc 2001; 54:751