Adriana Bigi

Prof. Adriana Bigi

Department of Chemistry “Giacomo Ciamician”

Alma Mater Studiorum University Of Bologna, Italy

Full Professor



1975 Degree in Chemistry, University of Bologna

Publications (selected)

  1. E. Boanini, P. Torricelli, F. Sima, E. Axente, M. Fini, I.N. Mihailescu, A. Bigi. Strontium and Zoledronate Hydroxyapatites Graded Composite Coatings for Bone Prostheses. Journal of Colloid and Interface Science 2015; 448: 1-7.
  2. S. Amadori, P. Torricelli, K. Rubini, M. Fini, S. Panzavolta, A. Bigi. Effect of sterilization and crosslinking on gelatin films. J Mater Sci: Mater Med 2015; 26: 69.
  3. E. Boanini, P. Torricelli, M. Gazzano, E. Della Bella, M. Fini, A. Bigi. Combined effect of strontium and zoledronate on hydroxyapatite structure and bone cell responses. Biomaterials 2014; 35: 5619-5626.
  4. S. Panzavolta, B. Bracci, C. Gualandi, M.L. Focarete, E. Treossi, K. Kouroupis-Agalou, K. Rubini, F. Bosia, L. Brely, N.M Pugno, V. Palermo, A. Bigi. Structural reinforcement and failure analysis in composite nano fibers of graphene oxide and gelatin. Carbon 2014; 78: 566–577.
  5. A. Fiorani, C. Gualandi, S. Panseri, M. Montesi, M. Marcacci, M.L. Focarete, A. Bigi. Comparative performance of collagen nanofibers electrospun from different solvents and stabilized by different crosslinkers. J Mater Sci: Mater Med 2014; 25: 2313–2321.
  6. S. Panzavolta, M. Gioffre, B. Bracci, K. Rubini, A. Bigi. Montmorillonite Reinforced Type A Gelatin Nanocomposites. J. Appl. Polym. Sci. 2014; 131, 40301.
  7. E. Boanini, P. Torricelli, M. C. Cassani, G. A. Gentilomi, B. Ballarin, K. Rubini, F. Bonvicini, A. Bigi. Cationic-anionic polyelectrolyte interaction as a tool to graft silver nanoparticles on hydroxyapatite crystals and prevent cytotoxicity. RSC Adv., 4, 2014; 645-652.
  8. P. Torricelli, M. Gioffrè, A. Fiorani, S. Panzavolta, C. Gualandi, M. Fini, M L Focarete, A. Bigi. Co-electrospun gelatin-poly(L-lactic acid) scaffolds: Modulation of mechanical 6 properties and chondrocyte response as a function of composition. Mater. Sci. Eng., C 2014; 36: 130-138.
  9. E. Boanini, P. Torricelli, M. Gazzano, M. Fini, A. Bigi. Crystalline Calcium Alendronate Obtained by Octacalcium Phosphate Digestion: A New Chance for Local Treatment of Bone Loss Diseases? 2013; 25: 4605–4611.
  10. S. Panzavolta, P. Torricelli, S. Amadori, A. Parrilli, K. Rubini, E. della Bella, M. Fini, A. Bigi. 3D interconnected porous biomimetic scaffolds: In vitro cell response. J Biom Mat Res A 2013, 101A: 3560–3570.
  11. E. Boanini, P. Torricelli, M. Gazzano, M. Fini, A. Bigi. The effect of alendronate doped calcium phosphates on bone cells activity. Bone 2012, 51: 944–952.
  12. E. Boanini, M. Gazzano, A. Bigi. Time Course of Zoledronate Interaction with Hydroxyapatite Nanocrystals J. Phys. Chem. C 2012, 116: 15812−15818.
  13. E. Boanini, P. Torricelli, M. Fini, F. Sima, N. Serban, I.N. Mihailescu, A. Bigi. Magnesium and strontium doped octacalcium phosphate thin films by matrix assisted pulsed laser evaporation. Journal of Inorganic Biochemistry 107, 2012; 65–72.
  14. E. Boanini, P. Torricelli, M. Gazzano, M. Fini, A. Bigi. The effect of zoledronate-hydroxyapatite nanocomposites on osteoclasts and osteoblast-like cells in vitro. Biomaterials 2012; 33: 722-730.
  15. E. Boanini, P. Torricelli, M. Fini, A. Bigi. Osteopenic bone cell response to strontium-substituted hydroxyapatite. Journal of Materials Science: Materials in Medicine 2011; 22: 2079-208.
  16. E. Boanini, A. Bigi. Biomimetic gelatin–octacalcium phosphate core–shell microspheres. Journal of Colloid and Interface Science 2011; 362: 594–599.
  17. S. Panzavolta, B. Bracci, K. Rubini, A. Bigi. Optimization of a biomimetic bone cement: Role of DCPD. Journal of Inorganic Biochemistry 2011; 105: 1060–1065.
  18. S. Panzavolta, M. Gioffrè, M. L. Focarete, C. Gualandi, L. Foroni, A. Bigi. Electrospun gelatin nanofibers: optimization of genipin crosslinking to preserve fiber morphology after exposure to water. Acta Biomater 2011; 7: 1702–1709.
  19. S. Panzavolta, P. Torricelli, B. Bracci, M. Fini, A. Bigi. Functionalization of biomimetic calcium phosphate bone cements with alendronate. J Inorg Biochem 2010; 104: 1099–1106.
  20. E. Boanini, M. Gazzano, K. Rubini, A. Bigi. Collapsed Octacalcium Phosphate Stabilized by Ionic Substitutions. Crys Growth Des 2010; 10: 3612–3617.
  21. E. Boanini, M. Gazzano, A. Bigi. Ionic substitutions in calcium phosphates synthesized at low temperature. Acta Biomater 2010; 6: 1882–1894.
  22. E. Boanini, S. Panzavolta, K. Rubini, M. Gandolfi, A. Bigi. Effect of strontium and gelatin on the reactivity of a-tricalcium phosphate. Acta Biomater 2010; 6: 936–942.
  23. E. Boanini, K. Rubini, S. Panzavolta, A. Bigi. Chemico-physical characterization of gelatin films modified with oxidized alginate. Acta Biomater 2010; 6: 383-388.
  24. B. Bracci, P. Torricelli, S. Panzavolta, E. Boanini, R. Giardino, A. Bigi. Effect of Mg2+, Sr2+, and Mn2+ on the chemico-physical and in vitro biological properties of calcium phosphate biomimetic coatings. J Inorg Biochem 2009; 103: 1666–1674.
  25. A. Bigi, E. Boanini, C. Capuccini, M. Fini, I.N. Mihailescu, C. Ristoscu, F. Sima, P. Torricelli. Biofunctional alendronate–Hydroxyapatite thin films deposited by Matrix Assisted Pulsed Laser Evaporation Biomaterials 2009; 30: 6168–6177.

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