David J. Riese II

Dr. David J. Riese II

Auburn University, USA



1993 Ph.D., Yale University School of Medicine, Genetics

1989 M. Phil., Yale University School of Medicine, Human Genetics

1987 A.B., Wabash College, Biology

Publications (Selected)

  1. C. Leptak, S Ramon y Cajal, R Kulke, BH Horwitz, DJ Riese II, GP Dotto, and D DiMaio. Tumorigenic transformation of murine keratinocytes by the E5 genes of bovine papillomavirus type 1 and human papillomavirus type 16. J Virology 65: 7078-7083 (1991). PMID: 1658398. PMCID: 250837.
  2. JK Selkirk, BK Mansfield, DJ Riese, A Nikbakht, and RC Mann. Two-dimensional gel electrophoretic comparison of cytoplasmic proteins in C3H10T1/2 cells, a chemically-transformed 10T1/2 line, and a transformation resistant C3H mouse ventral prostate cell line. Appl Theoret Electrophoresis 2: 43-51 (1991). PMID: 1932209.
  3. ES Hwang, DJ Riese II, J Settleman, LA Nilson, J Honig, S Flynn, and D DiMaio. Inhibition of cervical carcinoma cell line proliferation by the introduction of a bovine papillomavirus regulatory gene. J Virology 67: 3720-3729 (1993). PMID: 8389903. PMCID: 237735.
  4. DJ Riese II, TM van Raaij, GD Plowman, GC Andrews, and DF Stern. The cellular response to neuregulins is governed by complex interactions of the erbB receptor family. Mol Cell Biol 15: 5770-5776 (1995). PMID: 7565730. PMCID: 230829.
  5. DJ Riese II and D DiMaio. An intact PDGF signaling pathway is required for efficient growth transformation of mouse C127 cells by the bovine papillomavirus E5 protein. Oncogene 10: 1431-1439 (1995). PMID: 7731695.
  6. DJ Riese II, Y Bermingham, TM van Raaij, S Buckley, GD Plowman, and DF Stern. Betacellulin activates the epidermal growth factor receptor and erbB4, and induces cellular response patterns distinct from those stimulated by epidermal growth factor or neuregulin-β. Oncogene 12:345-353 (1996). PMID: 8570211.
  7. DJ Riese II, ED Kim, K Elenius, S Buckley, M Klagsbrun, GD Plowman, and DF Stern. The epidermal growth factor receptor couples transforming growth factor alpha, amphiregulin, and heparin-binding EGF-like growth factor to neu, erbB3, and erbB4. J Biol Chem 271: 20047-20052 (1996). PMID: 8702723.
  8. S Kannan, M De Santis, M Lohmeyer, DJ Riese II, GH Smith, N Hynes, M Seno, R Brandt, C Bianco, G Persico, N Kenney, N Normanno, I Martinez-Lacaci, F Ciardiello, DF Stern, WJ Gullick, and D Salomon. Cripto enhances the tyrosine phosphorylation of shc and activates map-kinase in mammary epithelial cells. J Biol Chem 272: 3330-3335 (1997). PMID: 9013573.
  9. H Chang, DJ Riese II, W Gilbert, DF Stern, and UJ McMahan. Ligands for erbB family receptors encoded by a newly characterized neuregulin-like gene. Nature 387: 509-512 (1997). PMID: 9168114.
  10. DJ Riese II and DF Stern. Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 20: 41-48 (1998). PMID: 9504046.
  11. DJ Riese II, T Komurasaki, GD Plowman, and DF Stern. Activation of ErbB4 by the bifunctional EGF family hormone epiregulin is regulated by ErbB2. J Biol Chem 273: 11288-11294 (1998). PMID: 9556621.
  12. C Sweeney, C Lai, DJ Riese II, AJ Diamonti, LC Cantley, and KL Carraway III. Ligand discrimination in signaling through an ErbB4 receptor homodimer. J Biol Chem 275: 19803-19807 (2000). PMID: 10867024.
  13. F Mu, SL Coffing, DJ Riese II, RL Geahlen, P Verdier-Pinard, E Hamel, J Johnson, and M Cushman. Design, synthesis, and biological evaluation of a series of Lavendustin A analogs which inhibit EGFR and Lck tyrosine kinases, as well as tubulin polymerization. J Med Chem 44: 441-452 (2001). PMID: 11462983.
  14. K Feroz, EE Williams, and DJ Riese II. ErbB2 and ErbB3 do not quantitatively modulate ligandinduced ErbB4 tyrosine phosphorylation. Cell Signal 14: 793-798 (2002). PMID: 12034361.
  15. DJ Penington, I Bryant, and DJ Riese II. Constitutively active ErbB4 and ErbB2 mutants exhibit distinct biological activities. Cell Growth Differ 13: 247-256 (2002). PMID: 12114214.
  16. SS Hobbs, SL Coffing, ATD Le, EM Cameron, EE Williams, M Andrew, EN Blommel, RP Hammer, H Chang, and DJ Riese II. Neuregulin isoforms exhibit distinct patterns of ErbB family receptor activation. Oncogene 21: 8442-8452 (2002). PMID: 12466964.
  17. J Walker-Daniels, DJ Riese II, and MS Kinch. c-Cbl dependent EphA2 protein degradation is induced by ligand binding. Mol Cancer Res 1: 79-87 (2002). PMID: 12496371.
  18. EE Williams, LJ Trout, RM Gallo, SE Pitfield, DJ Penington, I Bryant, and DJ Riese II. A constitutively-active ErbB4 mutant inhibits drug-resistant colony formation by the DU-145 and PC-3 human prostate tumor cell lines. Cancer Lett 192: 67-74 (2003). PMID: 12637154.
  19. SS Hobbs, EM Cameron, RP Hammer, ATD Le, RM Gallo, EN Blommel, SL Coffing, and DJ Riese II. Five carboxyl-terminal residues of Neuregulin2 are critical for stimulation of signaling by the ErbB4 receptor tyrosine kinase. Oncogene 23: 883-894 (2004). PMID: 14661053.