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Biography
7

Dr. Eran Meshorer

The Hebrew University of Jerusalem, Israel


Email: meshorer@cc.huji.ac.il


Qualifications


2003 Ph.D., Molecular neuroscience, The Hebrew University of Jerusalem

1999 M.Sc., Molecular microbiology, The Hebrew University of Jerusalem

1996 B.Sc., Biology, The Hebrew University of Jerusalem


Publications(Selected)

  1. Nissim-Rafinia M and Meshorer E (2011) Fluorescence recovery after photobleaching of chromatin proteins in embryonic stem cells. J Vis Exp. In press.
  2. Badi Sri, S, Takizawa T and Meshorer E (2010) Chromatin immunoprecipitation (ChIP) in mouse hippocampal cells and tissues. Methods Mol Biol, In press.
  3. Gaspar-Maia A, Alajem A, Meshorer E and Ramalho-Santos M (2010) Open chromatin in stem cells and pluripotency. Nat Rev Mol Cell Biol, 12(1):36-47.
  4. Mattout, A and Meshorer E (2010) Chromatin and nuclear architecture in pluripotent embryonic stem cells. Curr Opin Cell Biol, 22:334-341.
  5. Schwartz S, Meshorer E and Ast G (2009) Chromatin organization marks exon-intron structure. Nat Struct Mol Biol. 16:990-996 (cover).
  6. Gaspar-Maia A, Alajem A, Polesso F, Sridharan R, Mason MJ, Heidersbach A, Ramalho-Santos J, McManus MT, Plath K, Meshorer E, Ramalho-Santos M (2009) Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature, 460: 863-868.
  7. Raghu Ram EVS and Meshorer E (2009) Transcriptional competence in pluripotency. Genes Dev. 23:2793-8.
  8. Efroni, S, Melcer S, Nissim-Rafinia M and Meshorer E (2009) Cells do play with dice: a statistical physics view of transcription. Cell Cycle. 8:43-48.
  9. Prokocimer M, Davidovich M, Nissim-Rafinia M, Wiesel-Motiuk N, Bar D, Barkan R, Meshorer E and Gruenbaum Y (2009) Nuclear lamins: key regulators of nuclear structure and activities. J Cell Mol Med. 13:1059-1085.
  10. Efroni S, Duttagupta R, Cheng J, Dehghani H, Hoeppner DJ, Dash C, Bazett-Jones DP, Le Grice S, McKay RDG, Buetow KH, Gingeras TR, Misteli T, Meshorer E (2008) Global transcription in pluripotent embryonic stem cells. Cell Stem Cell, 2:437-447.
  11. Takizawa T and Meshorer E (2008) Chromatin and nuclear architecture in the central nervous system. Trends Neurosci. 31:343-352.
  12. Meshorer E and Gruenbaum Y (2008) Gone with the Wnt/Notch: stem cells in laminopathies, progeria and aging. J Cell Biol. 181:9-13.
  13. Meshorer E (2008) Imaging chromatin in embryonic stem cells. StemBook, doi/10.3824/stembook.1.2.1, http://www.stembook.org.
  14. Meshorer E (2007) Chromatin in embryonic stem cell neuronal differentiation. Histol. istopathol. 22:311-319.
  15. Meshorer E, Yellajoshula D, George E, Scambler PJ, Brown D and Misteli T (2006) Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Dev Cell, 10:105-116.
  16. Meshorer E and Soreq H (2006) Virtues and woes of acetylcholinesterase alternative splicing in stress related neuropathology. Trends Neurosci. 29:216-224.
  17. Meshorer E, Bryk B, Toiber D, Cohen J, Podoly E, Dori A and Soreq H (2005) SC35 promotes sustainable stress-induced alternative splicing of neuronal acetylcholinesterase mRNA. Mol. Psych. 10:985-997. [Lilly award winner. Cover].
  18. Meshorer E, Biton I, Ben-Shaul Y, Assaf Y, Soreq H and Cohen Y (2005) Brain diffusion and transport abnormalities under cholinergic imbalance. FASEB J. 19:910-22.
  19. Meshorer E, Toiber D, Zurel D, Sahly I, Dori A, Cagnano E, Schreiber L, Grisaru D, Tronche F and Soreq H (2004) Combinatorial Complexity of 5’ Alternative ACHE Transcripts and Protein Products. J. Biol. Chem. 279:29740-29751.
  20. Stoilov P, Meshorer E, Gencheva M, Glick D, Soreq H and Stamm S (2002) Defects in pre-mRNA processing as causes of and predisposition to diseases. DNA Cell Biol. 21:803-818
  21. Meshorer E and Soreq H (2002) Pre-mRNA splicing modulations in senescence. Aging Cell 1:10-16 (Cover).
  22. Meshorer E, Erb C, Gazit R, Pavlovsky L, Kaufer D, Friedman A, Glick D, Ben-Arie N and Soreq H (2002) Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity. Science, 295:508-512.
  23. Lev-Lehman E, Evron T, Broide RS, Meshorer E, Ariel I, Seidman S and Soreq H (2000) Synaptogenesis and myopathy under acetylcholinesterase overexpression. J. Mol. Neurosci. 14:93-105.
  24. Sigalevich P, Meshorer E, Helman Y and Cohen Y (2000) Transition from anaerobic growth conditions of the sulfate reducing bacterium Desufovibrio oxyclinae resulting in floculation. Appl. Environ. Microbiol. 66:5005-5012