Jacques Nör

Prof. Jacques E. Nör

Department of Cardiology

University of Michigan, USA



2001    Post-doc, University of Michigan Medical School, Cancer Cell Biology

1999    Ph.D., University of Michigan Dental School, Oral Health Sciences

1994    M.S., University of Michigan Dental School, Pediatric Dentistry

1990    Certificate, Brazilian Federal University, Pediatric Dentistry

1985    D.D.S., Brazilian Federal University, Dentistry

Publications (Selected)

  1. Imai A, Zeitlin BD, Visioli F, Dong Z, Zhang Z, Krishnamurthy S, Light E, Worden F, Wang S, Nör JE. Metronomic regimen enhances the anti-tumor and anti-angiogenic effect of the BH3-mimetics drug AT101. Cancer Res (In press).
  2. Casagrande L, Cordeiro MM, Nör SA, Nör JE. Dental Pulp Stem Cells in Regenerative Dentistry. Odontology 2011;99:1-7.
  3. Morelli T, Neiva R, Nevins ML, McGuire MK, Scheyer ET, Oh TJ, Braun TM, Nör JE, Bates D, Giannobile WV. Angiogenic Markers and Healing of Living Cellular Constructs. J Dent Res 2011 Jan 19. [Epub ahead of print]
  4. Sakai VT, Cordeiro MM, Dong Z, Zhang Z, Zeitlin BD, Nör JE. Tooth Slice/Scaffold Model of Dental Pulp Tissue Engineering. Adv Dent Res (in press).
  5. Krishnamurthy S, Dong Z, Vodopyanov D, Imai A, Helman JI, Prince ME, Wicha MS, Nör JE. Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells. Cancer Res 70:9969-9978, 2010.
  6. Zhang Z, Neiva K, Lingen MW, Ellis LM, Nör JE. VEGF-dependent tumor angiogenesis requires the inverse and reciprocal regulation of VEGFR1 and VEGFR2. Cell Death Diff 17:499-512, 2010.
  7. Zeitlin BD, Spalding AC, Campos MS, Ashimori N, Dong Z, Wang S, Lawrence TS, Nör JE. Metronomic small molecule inhibitor of Bcl-2 is anti-angiogenic and potentiates the anti-tumor effect of ionizing radiation. Int J Radia Oncol 78:879-887, 2010 (Highlights section).
  8. Giordano RJ, Cardó-Vila M, Salameh A, Anobom CD, Zeitlin BD, Hawke DH, Valente AP, Almeida FC, Nör JE, Sidman RL, Pasqualini R, Arap W. From combinatorial peptide selection to drug prototype (I): Targeting the vascular endothelial growth factor receptor pathway. Proc Natl Acad Sci USA 107:5112-5117, 2010.
  9. Casagrande L, Demarco F, Zhang Z, Araujo FB, Shi S, Nör JE. Dentin-derived BMP2 and odontoblastic differentiation of SHED. J Dent Res 89:603-608, 2010 (Journal Cover).
  10. Sakai VT, Zhang Z, Dong Z, Neiva K, Machado M, Shi S, Santos C, Nör JE. SHED Differentiate Into Functional Odontoblasts and Endothelium. J Dent Res 89:791-796, 2010.
  11. Demarco F, Casagrande L, Zhang Z, Dong Z, Tarquinio S, Zeitlin B, Shi S, Smith A, Nör JE. The effects of morphogen and scaffold porogen on the differentiation of dental pulp stem cells. J Endod 36:1805-1811, 2010 (Journal cover).
  12. Chokechanachaisakul U, Kaneko T, Okiji T, Kaneko R, Suda H, Nör JE. Laser Capture Microdissection in Dentistry. Int J Dent 2011 Jan 13. [Epub ahead of print]
  13. Botero TM, Son JS, Vodopyanov D, Shelburne CE, Nör JE. MAPK signaling is required for LPS-induced VEGF in pulp stem cells. J Dent Res 89:264-269, 2010 (Journal cover).
  14. Liu J, Jin T, Chang S, Czajka-Jakubowska A, Zhang Z, Nör JE, Clarkson BH. The effect of novel fluorapatite (FA) surfaces on osteoblast-like cell adhesion, growth and mineralization. Tissue Engineering Part A 16:2977-2986, 2010.
  15. Aranha A, Zhang Z, Neiva KG, Costa CA, Hebling J, Nör JE. Hypoxia enhances the angiogenic potential of human dental pulp cells. J Endod 36:1633-1637, 2010.
  16. Kim J, Shukla R, Casagrande L, Nör JE, Baker J, Hill E. Dendrimer-RGD Conjugates Enhance Dental Pulp Cell Differentiation. J Dent Res 89:1433-1438, 2010.
  17. Nedel F, Soki FN, Conde MC, Zeitlin BD, Tarquinio SB, Nör JE, Seixas FK, Demarco FF. Comparative analysis of two colorimetric assays in dental pulp cell density. Int Endod J 44:59-64, 2011.
  18. Zhang R, Cooper P, Smith G, Nör JE, Smith AJ. Angiogenic activity of dentin matrix components”. J Endod 37:26-30, 2011.
  19. Zeitlin BD, Nör JE. Small-Molecule Inhibitors Reveal a New Function for Bcl-2 as a Proangiogenic Signaling Molecule. Curr Top Microbiol Immunol 2010 Oct 13. [Epub ahead of print].
  20. Hegen A, Blois A, Tiron CE, Hellesøy M, Micklem DR, Nör JE, Akslen LA, Lorens JB. Efficient in vivo vascularization of tissue engineering scaffolds. J Tissue Engin Regen Med 2010 Sep 23. [Epub ahead of print].