Prof. Antonio Giordano

University of Siena, Italy



2002-present Director, Sbarro Institute for Cancer Research and Molecular Medicine & Professor of Biology, College of Science and Technology, Temple University, Philadelphia, PA

2001-2002 Professor, Depts. of Pathology, Anatomy & Cell Biology, Jefferson Medical College, Philadelphia, PA

1996-2001 Associate Professor, Depts. of Pathology, Anatomy & Cell Biology Jefferson Medical College, Philadelphia, PA

1994-1996 Assistant Professor, Depts. of Microbiology-Immunology and Pathology, Kimmel Cancer Institute, Jefferson Medical College, Philadelphia, PA


  1. Esposito L, Caligiuri I, Giordano A. Treatment for glioma recurrence: new hope Cancer Biol Ther. 2010 Jan;9(1):40-41. Epub 2010 Jan 1. No abstract available.
  2. Di Bernardo G, Galderisi U, Fiorito C, Squillaro T, Cito L, Cipollaro M, Giordano A, Napoli C. Dual role of parathyroid hormone in endothelial progenitor cells and marrow stromal mesenchymal stem cells. J Cell Physiol. 2010 Feb;222(2):474-480.
  3. Mattioli E, Giordano A, Pentimalli F. Predicting breast cancer outcome: Traditional prognosticators still on center stage. Cancer Biol Ther. 2010 Feb 22;9(4).
  4. D'Urso V, Collodoro A, Mattioli E, Giordano A, Bagella L. Cytometry and DNA ploidy: clinical uses and molecular perspective in gastric and lung cancer. J Cell Physiol.2010 Mar;222(3):532-539. Review.
  5. Balestrieri ML, Lu SJ, de Nigris F, Giovane A, Williams-Ignarro S, D'Armiento FP, Feng Q, Fiorito C, Testa G, Pastore L, Cacciatore F, Mancini FP, Servillo L, De Rosa G, Pagliarulo C, Rienzo M, Minucci PB, Farzati B, Salvatore F, Rengo F, Ignarro LJ, Giordano A, Baker A, Lanza R, Napoli C. Therapeutic angiogenesis in diabetic apolipoprotein E-deficient mice using bone marrow cells, functional hemangioblasts and metabolic intervention. Atherosclerosis. 2010 Apr;209(2):403-414. Epub 2009 Oct 29.
  6. Caracciolo V, Macaluso M, D'Agostino L, Montanari M, Scheff J, Reiss K, Khalili K, Giordano A. Cross-talk between T-Ag presence and pRb family and p53/p73 signaling in mouse and human medulloblastoma. J Cell Biochem. 2010 May;110(1):182-190.
  7. D'Agostino L, Caracciolo V, Giordano A. NSP 5a3a's link to nuclear-cyto proteins B23 and hnRNP-L between normal and aberrant breast cell lines. Cell Cycle. 2010 Mar 18;9(6). [Epub ahead of print]
  8. Rizzolio F, Tuccinardi T, Caligiuri I, Lucchetti C, Giordano A. CDK inhibitors: from the bench to clinical trials. Curr Drug Targets. 2010 Mar;11(3):279-290. Review.
  9. Caracciolo V, D'Agostino L, Dráberová E, Sládková V, Crozier-Fitzgerald C, Agamanolis DP, de Chadarévian JP, Legido A, Giordano A, Dráber P, Katsetos CD. Differential expression and cellular distribution of gamma-tubulin and betaIII-tubulin in medulloblastomas and human medulloblastoma cell lines. J Cell Physiol. 2010 May;223(2):519-529.
  10. Indovina P, Giordano A. Targeting the checkpoint kinase WEE1: Selective sensitization of cancer cells to DNA-damaging drugs. Cancer Biol Ther. 2010 Apr 22;9(7). [Epub ahead of print] No abstract available.
  11. Squillaro T, Alessio N, Cipollaro M, Renieri A, Giordano A, Galderisi U. Partial silencing of methyl cytosine protein binding 2 (MECP2) in mesenchymal stem cells induces senescence with an increase in damaged DNA. FASEB J. 2010 May;24(5):1593-1603. Epub 2010 Jan 11.
  12. Rizzolio F, Esposito L, Muresu D, Fratamico R, Jaraha R, Caprioli GV, Giordano A. RB gene family: genome-wide ChIP approaches could open undiscovered roads. J Cell Biochem. 2010 Apr 1;109(5):839-843. Review.
  13. Indovina P, Acquaviva A, De Falco G, Rizzo V, Onnis A, Luzzi A, Giorgi F, Hadjistilianou T, Toti P, Tomei V, Pentimalli F, Carugi A, Giordano A. Downregulation and aberrant promoter methylation of p16INK4A: a possible novel heritable susceptibility marker to retinoblastoma. J Cell Physiol. 2010 Apr;223(1):143-150.
  14. Naviglio S, Di Gesto D, Illiano F, Chiosi E, Giordano A, Illiano G, Spina A.Leptin potentiates antiproliferative action of cAMP elevation via protein kinase A downregulation in breast cancer cells. J Cell Physiol. 2010 Jun 29. [Epub ahead of print]
  15. Tuccinardi T, Botta M, Giordano A, Martinelli A. Protein kinases: docking and homology modeling reliability. J Chem Inf Model. 2010 Aug 23;50(8):1432-41.
  16. Federico M, Symonds CE, Bagella L, Rizzolio F, Fanale D, Russo A, Giordano A. R-Roscovitine (Seliciclib) prevents DNA damage-induced cyclin A1 upregulation and hinders non-homologous end-joining (NHEJ) DNA repair. Mol Cancer. 2010 Aug 4;9:208.
  17. de Nigris F, Crudele V, Giovane A, Casamassimi A, Giordano A, Garban HJ, Cacciatore F, Pentimalli F, Marquez-Garban DC, Petrillo A, Cito L, Sommese L, Fiore A, Petrillo M, Siani A, Barbieri A, Arra C, Rengo F, Hayashi T, Al-Omran M, Ignarro LJ, Napoli C. CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14484-9. Epub 2010 Jul 26.
  18. Terracciano D, Mazzarella C, Di Carlo A, Mariano A, Ferro M, Di Lorenzo G, Giordano A, Altieri V, De Placido S, Macchia V. Effects of the ErbB1/ErbB2 kinase inhibitor GW2974 on androgen-independent prostate cancer PC-3 cell line growth and NSE, chromogranin A and osteopontin content. Oncol Rep. 2010 Jul;24(1):213-7.
  19. Fiorito F, Marfè G, Granato GE, Ciarcia R, De Blasio E, Tafani M, Florio S, De Martino L, Muzi G, Pagnini U, Giordano A. 2,3,7,8-Tetrachlorodibenzo-p-dioxin modifies expression and nuclear/cytosolic localization of Bovine Herpesvirus 1 immediate-early protein (bICP0) during infection. J Cell Biochem. 2010 May 12. [Epub ahead of print]
  20. Ciarcia R, d'Angelo D, Pacilio C, Pagnini D, Galdiero M, Fiorito F, Damiano S, Mattioli E, Lucchetti C, Florio S, Giordano A. Dysregulated calcium homeostasis and oxidative stress in chronic myeloid leukemia (CML) cells. J Cell Physiol. 2010 Aug;224(2):443-53.
  21. Rizzolio F, La Montagna R, Tuccinardi T, Russo G, Caputi M, Giordano A. Adenosine receptor ligands in clinical trials. Curr Top Med Chem. 2010;10(10):1036-45.
  22. Rossi A, Schenone S, Angelucci A, Cozzi M, Caracciolo V, Pentimalli F, Puca A, Pucci B, La Montagna R, Bologna M, Botta M, Giordano A. New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells. FASEB J. 2010 Aug;24(8):2881-92. Epub 2010 Mar 30.
  23. D'Andrilli G, Bovicelli A, Giordano A. HPV vaccines: state of the art. J Cell Physiol. 2010 Sep;224(3):601-4. Review.
  24. Piscitelli P, Iolascon G, Greco M, Marinelli A, Gimigliano F, Gimigliano R, Gisonni P, Giordano A, Migliore A, Granata M, Tarantino U, Brandi ML, Baggiani A, Distante A.The Occurence of Acute Myocardial Infarction in Italy: a Five-years Analysis of Hospital Discharge Records. Aging Clin Exp Res. 2010 Jul 21. [Epub ahead of print]
  25. Aloisi AM, Ceccarelli I, Fiorenzani P, Maddalena M, Rossi A, Tomei V, Sorda G, Danielli B, Rovini M, Cappelli A, Anzini M, Giordano A. Aromatase and 5-alfa Reductase Gene Expression: Modulation by Pain and Morphine Treatment in Male Rats. Mol Pain. 2010 Oct 26;6(1):69. [Epub ahead of print]
  26. Cito L, Pentimalli F, Forte I, Mattioli E, Giordano A. Rb family proteins in gastric cancer (Review). Oncol Rep. 2010 Dec; 24(6): 1411-1418.