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Biography
Dr. Daniel J. Canney

Dr. Daniel J. Canney

The Chair of the department of Pharmaceutical Sciences

Temple University, USA


Email: canney@temple.edu


Qualifications


1990 Postdoctoral Fellow, Department of Pharmacology and Molecular Biology, Washington University, School of Medicine, St. Louis, MO

1986 Ph.D., Medicinal Chemistry, Temple University

1979 B.S., Pharmacy, Temple University


Publications (Selected)

  1. Canney, D.J.:  Monographs on Cholinomimetic Drugs in Remington:  The Science and Practice of Pharmacy, 22nd Edition, Loyd V. Allen (ed.), Pharmaceutical Press, London, UK, September, 2012.
  2. Canney, D.J.: Monographs on Antimuscarinic and Antispasmodic Drugs inRemington:  The Science and Practice of Pharmacy, 22nd Edition, Loyd V. Allen (ed.), Pharmaceutical Press, London, UK, September, 2012.
  3. Canney, D.J.: Chapter 71:  Cholinomimetic Drug in Remington: The Science and Practice of Pharmacy, 21st Edition, A.R. Gennaro (ed.), Lippincott, Williams & Wilkins, Baltimore, MD, 2005.
  4. Canney, D.J.: Chapter 73:  Antimuscarinic and Antispasmodic Drugs in Remington:  The Science and Practice of Pharmacy, 21st Edition, A.R. Gennaro (ed.), Lippincott, Williams & Wilkins, Baltimore, MD, 2005.
  5. Bhandare, R., Canney, D.J., and Kharkar, P. Novel γ-Butyrolactone Derivatives as Muscarinic Receptor Antagonists: Pharmacophore Elucidation and Docking Analyses,Proceedings of ICPAC, Springer, 2014.
  6. Gao, R., Fan, R., Canney, D.J.  Synthesis of β,β-disubstituted γ-butyrolactones by chemoselective oxidation of 1,4-diols and γ-hydroxy olefins with RuCl3/NaIO4, Synlett,2015, 26(05): 661-66. (DOI: 10.1055/s-0034-1379614)
  7. Bhandare, R., Canney, D.J. Bioisosteric replacement in the design, synthesis and evaluation of ligands for muscarinic acetylcholine receptors, Medicinal Chemistry Journal (Bentham), 2014, 10(4):361-375.
  8. Gao, R., Bhandare, R., Canney, D.J. Homologation as a lead modification approach en route to a series of lactone-based muscarinic ligands, Medicinal Chemistry Research,2014, 23(2):1023–1030
  9. Annadurai, S., Martinez, R., Canney, D.J., Dunman, P.M., Abou-Gharbia, M. Promising 2-aminothiazole based antimicrobial leads against MRSA strains. Bioorg. Med. Chem. Lett., 2012 Dec 15;22(24),7719-7725.
  10. Sharan, S., Iwuchukwu, O. F., Canney, D.J., Zimmerman, C.L., Nagar, S. In-vivo Formed Versus Preformed Metabolite Kinetics of Trans-resveratrol-3-sulfate (R3S) and Trans-resveratrol-3-glucuronide (R3G). Drug Metab Dispos., 2012 Oct;40(10):1993-2001.
  11. Iwuchukwu, O. F., Sharan, S., Canney, D.J., Nagar, S.   Analytical method development for conjugated metabolites of trans-resveratrol, and application to pharmacokinetic studies. J. Pharm. Biomed. Anal. 2012, 63, 1-8.
  12. Nantogmah, S., Desai, S., Bhandare, R., Gabriel, J., Soprano, D., Canney, D.J. Synthesis and Preliminary Evaluation of Affinity for Retinoic Acid Receptors for Novel Organosilicon-Based retinoids. Pharmaceutical Chemistry Journal, 2012, 45(10), 612-621.
  13. Annadurai, S., Canney, D.J., Lebo, D, Krynetskaia, N., Krynetskiy, E.  Are glycyrrhizin derivatives specific inhibitors of HMGB1/DNA interactions? Der Pharmacia Lettre, 2011,3(3), 470-477.
  14. Gao, R., Canney, D.J.  A Versatile and Practical Microwave Assisted Synthesis of Sterically Hindered N-Aryl Piperazines, J. Org. Chem., 2010, 75(21), 7451–7453.
  15. Annadurai, S., Krynetskaia, Phadke, M.S., Krynetskiy, E., Canney, D.J.  Inhibition of sequence independent DNA-binding activity of human recombinant HMGB1 protein with natural triperpines. Der Pharmacia Lettre, 2010, 2(3), 432-443.
  16. Bhandare, R.R., Canney, D.J.  Modifications to five-substituted 3,3-diethyl-4,5-dihydro-2(3H)-furanones en route to novel muscarinic receptor ligands. Medicinal Chemistry Research, 2010, 20 (5), 558-565.
  17. Crismon, M.L., Albright, F.S., Canney, D.J., Das, N,G,, Mehanna, A,S,, Welage, L,S,, Wu-Pong, S., Miller, K.W. The role of dual-degree programs in colleges and schools of pharmacy: the report of the 2008-09 Research and Graduate Affairs Committee. Am J Pharm Educ. 2009;73, Suppl:S6.
  18. Gao, R., Canney, D.J.  A modified Prins reaction for the facile synthesis of structurally diverse substituted 5-(2-hydroxyethyl)-3,3-dihydrofurane-2(3H)-ones. Tetrahedron Lett.,2009, 50;43, 5914-5916.
  19. Sun, W., Carroll, P.J., Soprano, D.,Canney, D.J. .Identification of a Chromone-Based Retinoid Containing a Polyolefinic Side Chains via Facile Synthetic Routes. Bioorg. Med Chem Lett. 2009, 19:15, 4339-42.