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Biography

Prof. Nour-Eddine Es-Safi

Mohammed V University in Rabat, Ecole Normale Supérieure -Rabat, Morocco


Email: nouressafi@yahoo.fr


Qualifications

1997 Ph.D., Rabat University, Organic Chemistry

1990 M.Sc., Ecole Normale Supérieure, Organic Chemistry


Publications (Selected)

  1. Mohamed Rida, Hamza El Meslouhi, Nour-Eddine Es-Safi, El Mokhtar Essassi,  Joseph Banoub. Structural fragmentation study of new synthetic benzodiazepine derivatives using electrospray ionization tandem mass spectroscopy. Rapid Communications in Mass Spectrometry 2008, 22, 2253-2268.
  2. Mohamed Rida, Hamza El Meslouhi, Noureddine Hammou Ahabchane, Bernard Garrigues, Nour-Eddine Es-Safi, El Mokhtar Essassi. A Convenient Method for the Synthesis of 1,5-benzodiazepin-2-one. The Open Organic Chemistry Journal 2008, 2, 83-87.
  3. Es-SAFI Nour-Eddine, Meudec Emmanuelle, Bouchut Claire, Fulcrand Hélène, Paul-Henri Ducrot, Herbette Gaëtan, Cheynier Véronique. New compounds obtained by evolution and oxidation of malvidin 3-O-glucoside in ethanolic medium. Journal of Agricultural and Food Chemistry 2008, 56, 4584-4591.
  4. Es-Safi Nour-Eddine, Christine Le Guernevé, Ducrot Paul-Henri. Application of NMR and MS Spectroscopy to the Structural Elucidation of Modified Flavan-3-ols and their Coupling Reaction Products.  Specroscopy Letters 2008, 41, 41-56.
  5. Guidouche Souhila, Es-Safi Nour-Eddine, Ducrot Paul-Henri. Mechanistic study on the enzymatic oxidation of flavonols. Tetrahedron Letters 2008, 49, 619-623.
  6. Es-Safi Nour-Eddine, Beauhaire Josiane, Ducrot Paul-Henri. Antioxidative activity of modified flavanols derivatives. American Journal of Food Technology 2007, 2, 618-629.
  7. Souhila Guidouche, Es-Safi Nour-Eddine, Ducrot Paul-Henri. Trametes versicolor laccase mediated oxidation of flavonoids. Influence of the hydroxylation pattern of ring B of flavonols. American Journal of Food Technology 2007, 2, 630-640.
  8. Es-Safi Nour-Eddine, Guidouche Souhila, Ducrot Paul-Henri. Flavonoids: Hemisynthesis, reactivity and antioxidative properties. Molecules 2007, 12, 2228-2258.
  9. Es-Safi Nour-Eddine, Lucien Kerhoas, Ducrot Paul-Henri. Fragmentation study of iridoid glucosides through positive and negative ESI/MS, CID/MS and tandem MS/MS. Rapid Communications in Mass Spectrometry 2007, 21, 1165-1175.
  10. Es-Safi Nour-Eddine, Lucien Kerhoas, Ducrot Paul-Henri. NMR Analysis and Fragmentation Study of Globularin through Positive and Negative ESI/MS, CID/MS and Tandem MS/MS. Specroscopy Letters 2007, 40, 695-714.
  11. Nathan Tene Ghomsi, Nour-Eddine Hammou Ahabchane, Nour-Eddine Es-Safi, El Mokhtar Essassi. Synthesis and Spectroscopic Stuctural Elucidation of New Quinoxaline Derivatives. Spectroscopy Letters 2007, 40, 741, 751.
  12. Es-Safi Nour-Eddine, Kollmann Albert, Khlifi Samira, Ducrot Paul Henri Antioxidative effect of compounds isolated from Globularia alypum L. Structure–activity relationship. LWT-Food Science and Technology 2007, 40, 1246-1252.
  13. Es-Safi Nour-Eddine, Khlifi Samira, Kollmann Albert, Ducrot Paul-Henri. Antioxidative activity of polyphenoolic compounds isolated from Globularia alypum L. Structure-activity relationship. Polyphenol Communications 2006, 493-494.
  14. Ghidouche Souhila, Es-Safi Nour-Eddine, Ducrot Paul-Henri. Importance of the substitution pattern of ring B of flavonols on their transformation by Trametes versicolor laccase. Polyphenol Communications 2006, 161-162.
  15. Es-Safi Nour-Eddine, Guyot Sylvain, Ducrot Paul Henri. NMR, ESI/MS and MALDI-TOF/MS analysis of pear juice polymeric proanthocyanidins with potent free radical scavenging activity. Journal of Agricultural and Food Chemistry 2006, 54, 6969-6977.
  16. Es-Safi Nour-Eddine, Beauhaire Josiane, Boyer François-Didier, Ducrot Paul-Henri. Substituent effects on flavanol couplings. Polyphenol Communications 2006, 57-58.
  17. Es-Safi Nour-Eddine, Khlifi Samira, Kollmann Albert, Kerhoas Lucien, El Abbouyi Ahmed, Ducrot Paul Henri Iridoid glucosides from the aerial parts of Globularia alypum L. (Globulariaceae). Chemical and Pharmaceutical Bulletin 2006, 54, 85-88.
  18. Es-Safi Nour-Eddine, Ducrot Paul Henri. Oxidation of flavan-3-ols: Gram-Scale synthesis of taxifolin. Letters in Organic Chemistry 2006, 3, 231-234.
  19. Khlifi Samira, Y. El Hachimi, Y. Khalil, Es-Safi Nour-Eddine, El Abbouyi Ahmed Antioxidant properties of Salvia verbenaca L. hydro-methanolic extract. Indian Journal of Pharmacology 2006, 38, 276-280.
  20. Es-Safi Nour-Eddine, Le Guernevé Christine, Kerhoas Lucien, Ducrot Paul Henri. Influence of an 8-trifluoroacetyl group on flavanol couplings. Tetrahedron 2006, 62, 2705-2714.
  21. Es-Safi Nour-Eddine, Kerhoas Lucien, Einhorn Jacques, Ducrot Paul-Henri Application of ESI/MS, CID/MS and tandem MS/MS to the fragmentation 2)-glucoside and luteolinàstudy of eriodictyol 7-O-glucosyl-(1 2)-glucoside. International Journal of Mass Spectrometry 2005, 247, 93-100.
  22. Es-Safi Nour-Eddine, Kerhoas Lucien, Ducrot Paul-Henri. Application of positive and negative ESI-MS, CID/MS and tandem MS/MS to a study of fragmentation of 6-hydroxyluteolin 7-O-glucoside and 3)-glucoside. Rapid Communications in Mass Spectrometry 2005, 19, 2734-2742.
  23. Es-Safi Nour-Eddine, Khlifi Samira, Kerhoas Lucien, Kollmann Albert, El Abbouyi Ahmed, Ducrot Paul-Henri. Antioxidant constituents of the aerial parts of Globularia alypum growing in Morocco. Journal of Natural Products 2005, 68, 1293-1296.
  24. Khlifi Samira, El Hachimi Y., Khalil A., Es-Safi Nour-Eddine, El Abbouyi Ahmed Antioxidant properties of Globularia alypum L. hydro-methanolic extract. Indian Journal of Pharmacology 2005, 37, 227-231.
  25. Boyer François Didier, Es-Safi Nour-Eddine, Beauhaire Josiane, Le Guernevé Christine, Ducrot Paul-Henri. Synthesis of modified proanthocyanidins: easy and general introduction of an hydroxy group at C-6 of catechin; efficient synthesis of elephantorrhizol. Bioorganic & Medicinal Chemistry Letters 2005, 15, 563-566.
  26. Beauhaire Josiane, Es-Safi Nour-Eddine, Boyer François Didier, Kerhoas Lucien, Le Guerneve Christine, Ducrot Paul-Henri. Synthesis of modified proanthocyanidins: introduction of acyl C-3à O àsubstituents at C-8 of catechin. Selective synthesis of a C-4 ether-linked procyanidin-like dimer. Bioorganic & Medicinal Chemistry Letters 2005, 15, 559-562.
  27. Es-Safi Nour-Eddine, Cheynier Véronique. Flavanols and anthocyanins as potent compounds in the formation of new pigments during storage and aging of red wine. In Red Wine Color - Exploring the Mysteries. Waterhouse AL, Kennedy JA (Eds), ACS Symposium, Series 886, Washington, DC, USA, 2004, 143-159.
  28. Es-Safi Nour-Eddine. Colour of a xanthylium pigment in aqueous solutions at different pH values. Food Chemistry 2004, 88, 367-372.
  29. 29. Es-Safi Nour-Eddine, Kerhoas Lucien, Boyer François Didier, Le Guerneve Christine, Ducrot Paul-Henri. Selective synthesis and structure of a C4-O-C3 ether-linked procyanidin-like dimer. Polyphenols Communications 2004, 578-579.
  30. Beauhaire Josiane, Boyer François Didier, Es-Safi Nour-Eddine, Le Guernevé Christine, Ducrot Paul-Henri. New methodologies for the synthesis of proanthocyanidins. Polyphenols Communications 2004, 73-74.
  31. Boyer François Didier, Es-Safi Nour-Eddine, Beauhaire Josiane, Le Guerneve Christine, Ducrot Paul-Henri. Hydroxylation on ring of the catechin, studies on the stability of resulting flavanol derivatives. Polyphenols Communications 2004, 577-578.
  32. Es-Safi Nour-Eddine, Cheynier Véronique, Moutounet Michel. Implication of phenolic reactions in food organoleptic properties. Journal of Food Composition and Analysis 2003, 16, 535-553.