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Biography
Dr. Reba Goodman

Prof. Reba Goodman

Columbia University Health Sciences,USA

Professor Emeritus Clinical Pathology; Special Lecturer in Pathology


Email: rmg5@columbia.edu


Qualifications

1956 Ph.D., Developmental Genetics, Columbia University, USA

1953 M.A., Developmental Genetics, Columbia University, USA

1949 B.A., Zoology and Botany, Indiana University, USA


Publications (Selected)

  1. Goodman R, Bassett CAL, Henderson A (1983) Pulsing electromagnetic fields induce cellular transcription. Science 220: 1283-1285.
  2. Goodman R and Henderson A (1986) Sine waves enhance cellular transcription. Bioelectromagnetics 7: 23-29.
  3. Goodman, R and Henderson, A (1988) Exposure of salivary gland cells to low-frequency electromagnetic fields alters polypeptide synthesis. Proc Natl Acad Sci (USA) 85: 3928-3932.
  4. Goodman, R, Wei, L-X Xu, J-C and Henderson, A (1989) Exposure of human cells to low-frequency electromagnetic fields results in quantitative changes in transcripts. Biochim Biophys Acta 1009: 216-220.
  5. Wei, L-X, Goodman, R and Henderson, A (1990) Changes in levels of c-myc and histone H2B following exposure of cells to low frequency sinusoidal electromagnetic fields: evidence for a window effect. Bioelectromagnetics 11: 269-272.
  6. Litovitz T, Montrose C, Goodman R, Elson E (1990) Power windows and transiently augmented transcription from exposure to electromagnetic radiation. Bioelectromagnetics 11: 250-266.
  7. Goodman, R and Henderson, A (1990) Exposure to cells to extremely low frequency electromagnetic fields: relationship to malignancy? Cancer Cells 2: 355-359.
  8. Goodman, R and Henderson A (1991) Transcription and translation in cells exposed to low frequency electromagnetic fields. Bioelectrochem Bioenerg 25: 335-355.
  9. Goodman R, Weisbrot D, Uluc A, Henderson, A (1992) Transcription in Drosophila melanogaster salivary gland cells is altered following exposure to low frequency electromagnetic fields: Analysis of chromosome 3R. Bioelectromagnetics13: 111-118.
  10. Goodman, R, Wei, L-X, Bumann, J, and Henderson, A (1992) Exposure to electric and magnetic fields increase transcripts in HL60 cells: does adaptation to EM fields occur? Bioelectrochem Bioenerg 29: 185-192.
  11. Goodman, R, Weisbrot, D, Uluc, A and Henderson, A (1992) Transcription in Drosophila melanogaster salivary gland cells is altered following exposure to low frequency electromagnetic fields: analysis of chromosomes 3L and X.Bioelectrochem Bioenerg 28:311-318.
  12. Goodman, R, Bumann, J, Wei, L-X and Henderson, AS (1992) Exposure of human cells to electromagnetic fields: effect of time and field strength on transcript levels. Electro-and Magnetobiology 11: 19-28.
  13. Blank, M, Soo, L, Henderson, A and Goodman, R (1992) Changes in transcription in HL60 cells following exposure to alternating currents from electric fields. Bioelectrochem Bioenerg 28: 301-309.
  14. Goodman, R, Chizmadzhev, Y and Hnderson, A (1993) Electromagnetic fields and cells. J Cellular Biochem 51: 436-441.
  15. Weisbrot D, Khorkova O, Lin H, Henderson A, Goodman, R (1993) The effect of low frequency electric and magnetic fields on gene expression in Saccharomyces cerevisiae Bioelectrochem Bioenerg 31: 167-177.
  16. Blank, M, Khorkova, O and Goodman, R (1993) Similarities in the proteins synthesized by Sciara salivary glands in response to electromagnetic fields and to heat shock. Bioelectrochem Bioenerg 31:27-38.
  17. Blank M, Khorkova O, Goodman, R (1994) Changes in polypeptide distribution stimulated by different levels of electromagnetic and thermal stress. Bioelectrochem Bioenerg 33: 109-114.
  18. Lin H, Goodman R, Henderson A (1994) Specific region of the c-myc promoter is responsive to electric and magnetic fields. J. Cell Biochem 55: 1-8.
  19. Karabakhtsian, R, Broude, N, Shalts, N, Kochlatyi, S, Goodman, R and Henderson, AS (1994) Calcium is necessary in the cell response to EM fields. FEBS Lett 349: 1-6.
  20. Broude, N, Karabakhtsian, Shalts, N, Goodman, R and Henderson, AS (1994) Correlation between amplitude of plasma membrane fluctuations and the response fo cells to electric and magnetic fields. Bioelectrochem Bioenerg 33: 19-23.
  21. Goodman R, Blank M, Lin H, Khorkova O, Soo L, Weisbrot D, Henderson, A (1994) Increased levels of hsp70 transcripts are induced when cells are exposed to low frequency electromagnetic fields. Bioelectrochem Bioenerg 33:115-120.
  22. Lin H, Blank M, Jin M, Lam H, Goodman, R (1996) Electromagnetic field stimulation of biosynthesis:changes in c-myc transcript levels during continuous and intermittent exposures. Bioelectrochem Bioenerg 39: 215-220.
  23. Opler, M, Rukenstein, L, Cote, L and Goodman, R (1997) Reduced dopamine levels in PC12 cells exposed to low frequency electromagnetic fields. Bioelectrochem Bioenerg 42: 235-240.
  24. Jin M, Lin H, Han L, Opler M, Maurer S, Blank M, Goodman, R (1997) Biological and technical variables in MYC expression in HL60 cells exposed to 60Hz electromagnetic fields. Bioelectrochem Bioenerg 44: 111-120.
  25. Blank, M and Goodman, R (1997) Do electromagnetic fields interact directly with DNA? Bioelectromagnetics 18: 111-115.
  26. Lin H, Opler M, Head M,Blank M, Goodman R (1997) Electromagnetic field exposure induces rapid transitory heat shock factor activation in human cells J Cell Biochem 66: 482-488.
  27. Goodman R and Blank M (1998) Magnetic field stress induces expression of hsp70. Cell Stress & Chaperones 3: 79-88.
  28. Lin H, Head M, Blank M, Jin M, Goodman R (1998a) Myc-mediated transactivation of HSP70 expression following exposure to magnetic fields J Cell Biochem 69: 181-188.
  29. Lin H, Han L, Blank M, Head M,Goodman R (1998b) Magnetic field activation of protein-DNA binding. J Cell Biochem: 70 297-303.
  30. Han L, Lin H, Jin M, Blank M, Goodman R (1998) Application of magnetic field-induced heat shock protein 70 for presurgical cytoprotection. J Cell Biochem 71: 577-583.
  31. Lin, H, Blank M, Head M, Goodman R (1999) Magnetic field-responsive domain in the human HSP70 promoter.J Cell Biochem 75: 170-176.
  32. Blank M and Goodman R (1999) Electromagnetic fields may act directly on DNA. J Cellular Biochem 75: 369-374.
  33. Jin M, Blank M, Goodman R (2000) ERK1/2 phosphorylation, induced by electromagnetic fields, diminishes during neoplastic transformation. J Cellular Biochem, 78: 371-379.
  34. Blank M, Goodman R (2000)Stimulation of the stress response by low frequency electromagnetic fields: Possibility of direct interaction with DNA. IEEE Trans. Plasma Sci 28: 168-172.
  35. Carmody S, Wu XL, Lin H, Blank M Goodman R (2000) Cytoprotection by electromagnetic field-induced hsp70: a model for clinical appl;ication. J Cellular Biochem, 79: 453-459.
  36. Lin H, Blank M, Goodman R (2001) Regulating genes with electromagnetic response elements. J Cellular Biochem, 81:143-148.
  37. Blank M and Goodman R (2001) Electromagnetic initiation of transcription at specific DNA sites. J Cellular Biochem 81: 689-692.
  38. Goodman R and Blank M (2002) Insights into electromagnetic interaction mechanisms. J Cellular Physiology 192:16-22.
  39. Blank M and Goodman R (2002) Biomedical applications of electromagnetic fields. In:( Kostarakis, Stavroulakis eds.) Millenium International Workshop on Biological Effects of Electromagnetic Fields, Proceedings, Haraklion, Crete, Greece. 17-20 October 2000, pp169-175, ISBN: 960-86733-0-5.
  40. Blank M, Goodman R (2002) Interaction of Weak Low Frequency Electromagnetic Fields with DNA: Mechanism and Biomedical Applications. IEEE Transactions on Plasma Science 30: 1497-1500.
  41. Blank M and Goodman R (2003) Stress Protein Synthesis and Enzyme Reactions are Stimulated by Electromagnetic Fields. In Magnetotherapy: Potential Therapeutic Benefits and Adverse Effects. MJ McLean, S Engström, RR Holcomb (eds), Floating Gallery Press, New York, pp. 19-28.
  42. Blank M and Goodman R (2003) Biomedical Applications of Electromagnetic Fields. In Biological Effects of Electromagnetic Fields, P Stavroulakis (ed), Springer, pp.494-502.
  43. Weisbrot D, Lin H, Ye L, Blank M, Goodman R (2003) Effects of Mobile Phone Radiation On Growth and Development In Drosophila melanogaster. J Cellular Biochemistry 89: 48-55.
  44. Blank M and Goodman R (2004) Initial interaction in electromagnetic field-induced biosynthesis. J Cell Physiol. 199: 359-363.
  45. Blank M and Goodman R (2004) A biological guide for electromagnetic safety: The stress response. Bioelectromagnetics 25(8):642-646.
  46. Blank M Goodman R (2004). Initial interactions in electromagnetic field-induced biosynthesis. J Cell Physiol 199:359-363.
  47. Blank M, Goodman R (2007). A mechanism for stimulation of biosynthesis by electromagnetic fields: charge transfer in DNA and base pair separation.
  48. Madkan A, Avary Lin-Ye, Spiro Pantazatos, Matthew S. Geddis, Martin Blank, Reba Goodman (2009).Frequency sensitivity of nanosecond pulse EMF on regrowth and hsp70 levels in transected planaria Ash J. Biomedical Science and Engineering, 2009, 4, 227-238.
  49. Althaus IW, Chou JJ, Gonzales AJ, Deibel MR, Chou KC, Kezdy FJ, Romero DL, Palmer JR, Thomas RC, Aristoff PA, Tarpley WG, Reusser F: Kinetic Studies with the Non-nucleoside HIV-1 Reverse Transcriptase Inhibitor U-88204E. Biochemistry, 32, 6548-6554 (1993).
  50. Althaus IW, Gonzales AJ, Chou JJ, Romero DL, Deibel MR, Chou KC, Kezdy FJ, Rensnick L, Busso ME, So AG, Downey KM, Thomas RC, Aristoff PA, Tarpley WG, Reusser F: The Quinoline U-78036 is a Potent Inhibitor of HIV-1 Reverse Transcriptase. J. Biol. Chem., 268, 14875-14880 (1993).