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Dr. Stefan Lorkowski

Friedrich Schiller University, Germany


Email: stefan.lorkowski@uni-jena.de


Qualifications

2009 Safety officer, Friedrich Schiller University, Germany

2008 Associate Professor, Friedrich Schiller University, Germany

2006-2008 Assistant Professor, Westphalian Wilhelms University, Germany

2004-2008 Biosafety officer, Leibniz Institute of Arteriosclerosis Research Münster, Germany


Publications (Selected)

  1. Rauch, U., Saxena, A., Lorkowski, S., Rauterberg, J., Durbeej‐Hjalt, M., Hultgårdh‐Nilsson, A. Laminin isoforms in atherosclerotic arteries from mice and man. Histology and Histopathology 2011
  2. Maeß, M.B., Sendelbach, S., Lorkowski, S. Selection of reliable reference genes during THP‐1 monocyte differentiation into macrophages. BMC Molecular Biology 2010; 11:90.  DOI: 10.1186/1471‐2199‐11‐90 This article was highlighted by BMC Molecular Biology as ‘highly accessed’.
  3. Lorkowski, S., Rauterberg, J., Harrach‐Ruprecht, B., Troyer, D.Collagen‐bound LDL modifies endothelial cell adhesion to type V.Central European Journal of Biology 2009; 4(4): 536‐542. DOI: 10.2478/s11535‐009‐0047‐8
  4. Lorkowski, S., Rauterberg, J., Harrach‐Ruprecht, B., Troyer, D.Collagen‐bound low density lipoprotein modifies endothelial cell adhesion to type V collagen: Implications for atherosclerosis. (No peer‐review) Nature Precedings 2007; 1‐4. DOI: 10.1038/npre.2007.1238.1
  5. Robenek, H., Buers, I., Hofnagel, O., Lorkowski, S., Severs, N.J.GFP‐tagged proteins visualized by freeze‐fracture immuno‐electron microscopy: a new tool in cellular and molecular medicine. Journal of Cellular and Molecular Medicine 2009; 13(7):1381‐1390. DOI: 10.1111/j.1582‐4934.2008.00407.x
  6. Schnoor, M., Buers, I., Sietmann, A., Brodde, M., Hofnagel, O., Robenek, H., Lorkowski, S. Efficient nonviral transfection of THP‐1 cells. Journal of Immunological Methods 2009; 344(2):109‐115. DOI: 10.1016/j.jim.2009.03.014
  7. Buers, I., Robenek, H., Lorkowski, S., Nitschke, Y., Severs, N.J., Hofnagel, O. TIP47, a lipid cargo protein involved in macrophage triglyceride metabolism. Arteriosclerosis, Thrombosis and Vascular Biology 2009; 29(5):767‐773. DOI: 10.1161/ATVBAHA.108.182675
  8. Tölle, M., Pawlak, A., Schuchardt, M., Kawamura, A., Tietge, U.J., Lorkowski, S., Keul, P., Assmann, G., Chun, J., Levkau, B., van der Giet, M., Nofer, J.‐R. HDL‐associated lysosphingolipids Inhibit NAD(P)H oxidase‐dependent monocyte chemoattractant protein‐1 production. Arteriosclerosis, Thrombosis and Vascular Biology 2008; 28(8):1542‐1548.
  9. DOI: 10.1161/ATVBAHA.107.161042
  10. Schmidt, A., Bilgasem, S., Lorkowski, S., Vischer, P., Völker, W., Breithardt, G., Siegel, G., Buddecke, E. Exogenous nitric oxide regulates activity and synthesis of vascular endothelial nitric oxide synthase. European Journal of Clinical Investigation 2008; 38(7): 476‐485. DOI: 10.1111/j.1365‐2362.2008.01967.x
  11. Schnoor, M., Cullen, P., Lorkowski, J., Stolle, K., Robenek, H., Troyer, D., Rauterberg, J., Lorkowski, S. Production of type VI collagen by human macrophages: a new dimension in macrophage functional heterogeneity. Journal of Immunology 2008; 180(8):5707‐5719.
  12. Broadbent, H.M., Peden, J.F. Lorkowski, S., Goel, A., Ongen, H., Green, F., Clarke, R., Collins, R., Franzosi, M.G., Tognoni, G., Seedorf, U., Rust, S., Eriksson, P., Hamsten, A., Farrall, M., Watkins, H., for the PROCARDIS consortium. Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked, SNPs in the ANRIL locus on chromosome 9p. Human Molecular Genetics 2008; 17(6):806‐814. DOI: 10.1093/hmg/ddm352
  13. Stolle, K., Schnoor, M., Fuellen, G., Spitzer, M., Cullen, P., Lorkowski, S. Cloning, genomic organization, and tissue‐specific expression of the TGF‐β1 inducible RASL11B gene. Biochimica et Biophysica Acta 2007; 1769(7‐8):514‐524. DOI: 10.1016/j.bbaexp.2007.05.005
  14. Uehara, Y., Miura, S., von Eckardstein, A., Abe, S., Fujii, A., Matsuo, Y., Rust, S., Lorkowski, S., Assmann, G., Yamada, T., Saku, K. Unsaturated fatty acids suppress the expression of the ATP‐binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsible element. Atherosclerosis 2007; 191(1):11‐21.DOI: 10.1016/j.atherosclerosis.2006.04.018