Dr. Harald John

Bundeswehr Institute of Pharmacology and Toxicology, Germany



1998 Ph.D., Westfälische Wilhelms-University Münster, Analytical Chemistry

1994 M.Sc., Westfälische Wilhelms-University Münster, Analytical Chemistry

1991 A.Sc., Westfälische Wilhelms-University Münster, Chemistry

Publications (selected)

  1. Gäb, J., John, H., Blum, MM. Formation of pyrophosphonate adducts from nerve agents sarin, soman and cyclosarin in phosphate buffer: implications for analytical and toxicological investigations. Toxicology Letters. 200 (2011) 34-40.
  2. John, H., Breyer, F., Thumfart, JO., Höchstetter, H., Thiermann, H. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for detection and identification of albumin phosphylation by organophosphorus pesticides and G- and V-type nerve agents. Analytical and Bioanalytical Chemistry. 398 (2010) 2677-2691.
  3. John, H., Eyer, F., Zilker, T., Thiermann, H. High-performance liquid-chromatographic tandem-mass spectrometric methods for atropinesterase-mediated enantioselective and chiral determination of R- and S-hyoscyamine in plasma. Analytica Chimica Acta. 680 (2010) 32-40.
  4. Becker, C., Worek, F., John, H. Chromatographic analysis of toxic phosphylated oximes (POX): a brief overview Drug Testing and Analysis 2 (2010) 460-468.
  5. Worek, F., Aurbek, N.,Herkert, N.M., John, H., Eddleston, M., Eyer, P., Thiermann, H., Evaluation of medical countermeasures against organophosphorus compounds: the value of experimental data and computer simulations. Chemico-Biological Interactions. 187 (2010) 259-264.
  6. Gäb, J., John, H., Melzer, M., Blum, MM., Stable adducts of nerve agents sarin and cyclosarin with buffer compounds TRIS and TES – Characterization by LC-ESI-MS/MS and NMR and implications for analytical chemistry. Journal of Chromatography. B 878 (2010) 1382-1390.
  7. John, H., Eddleston, M., Clutton, R.E., Worek, F., Thiermann, H., Simultaneous quantification of the organophosphorus pesticides dimethoate and omethoate in porcine plasma and urine by LC-ESI MS/MS and flow-injection ESI-MS/MS. Journal of Chromatography. B 878 (2010) 1234-1245.
  8. John, H., Thiermann, H. Preface: Bioanalysis of organophosphorus toxicants and corresponding antidotes Journal of Chromatography B 878 (2010) 1205-1206.
  9. Blum, MM., Tomanicek, SJ., John, H., Leif Hanson, B., Rüterjans, H., Schoenborn, BP., Langan, P., Chen, JCH., X-ray structure of perdeuterated diisopropyl fluorophosphatase (DFPase): Perdeuteration of proteins for neutron diffraction. Acta Crystallographica Section. F 66 (2010) 379-385.
  10. Thiermann, H., Gonder, S., John, H., Kehe, K., Koller, M., Steinritz, D., Worek, F., Chemische Kampfstoffe In: "Toxikologie- Band 2: Toxikologie der Stoffe", 1st Ed.; (HW. Vohr, ed.) Wiley-VCHWeinheim, Germany. (2010) 201-233.

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