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Biography
Dr. Izabela Tworowska

Dr. Izabela Tworowska

Therapeutic Nuclear Medicine Research Institute, USA


Email: izabela.tworowska@gmail.com


Qualifications


2001 Ph.D., Polish Academy of Sciences, Poland

1992 M.Sc., Pharm., Clinical Pharmacy, Medical University, Poland


Publications (selected)

  1. I. Tworowska, H. Saso, J. Sims-Mourtada, F. Mourtada, E. Delpassand and A. Azhdarinia, 68Ga-glucosamine analogs for PET imaging of cancer, J Nucl Med. 2009; (50) 376.
  2. I. Tworowska, H. Saso, J. Sims-Mourtada, A. Azhdarinia, Synthesis and properties of 68Ga-MPC-glucosamine conjugates for PET imaging of cancer, ACS National Meeting, 2009.
  3. Tworowska and E. ψ32, ψ39-modified anticodon arm of P. Nikonowicz, Base pairing within the Escherichia coli tRNAPhe , J. Am. Chem. Soc., 2006, 128 (49), 15570-15571.
  4. Jaroniec CP, Boisbouvier J, Tworowska I, Nikonowicz EP, Bax A, Accurate measurement of 15N-13C residual dipolar couplings in nucleic acids, J Biomol NMR., 2005, 31(3), 231-41.
  5. W. Dabkowski, A. Ozarek and I. Tworowska, Highly selective O-phosphitylation of amino alcohols using PIII reagents containing 4-nitro and 2,4-dinitroaryloxy leaving groups, New Journal of Chemistry, 2005, (29), 1396-1399.
  6. W. Dabkowski and I. Tworowska, Synthesis of phosphorofluoridates and phosphorofluorido-thioates via phosphoramidite approach, Org. Biomol. Chemistry, 2005, 3, 866-874.
  7. J. Cabello-Villegas, I. Tworowska and E. P. Nikonowicz, Metal Ion Stabilization of the U-turn of the A37 N6-dimethylally-Modified Anticodon Stem Loop of Escherichia coli tRNAPhe, Biochemistry 2004, 43, 55-56.
  8. Tworowska, W. Dabkowski and J. Michalski, The Phosphorofluoroamidite Aproach to Mixed Phosphites, J. Organometalic Chem. 2002, 643-644, 490-493.
  9. Tworowska, W. Dabkowski and J. Michalski, Synthesis of P-Fluorodithioacids of Phosphorus and their Synthetic Application, Phosphorus, Sulfur and Silicon, 2002, 177, 1855-1858.
  10. W. Dabkowski and I. Tworowska Synthesis of Phosphorofluoridates and Phosphorofluorido-thioates via the Phosphoramidite Approach., J. Chem. Soc., Perkin Trans. 1, 2001, 2462-2469.
  11. Tworowska, W. Dabkowski, and J. Michalski, Novel Synthesis of Tri- and Tetra-coordinate Phosphorus Compounds Containing the P-trifluoromethyl Group by Nucleophilic Trifluoromethylation of the Corresponding P-Fluoro Systems., Angew. Chem. Int. Ed. 2001 40(15), 2898-2990.
  12. W. Dabkowski, I. Tworowska, J. Michalski, F. Cramer, New Efficient Synthesis of Thymidine Cyclic 3', 5'-Phosphorofluoridate and Its Sulfur Analogue via the Phosphoroamidite Route, Nucleosides & Nucleotides, 2000, 19 (10&12), 1779-1785.
  13. W. Dabkowski, I. Tworowska, J. Michalski, F. Cramer, 2, 4-Dinitrophenol: a Novel Activating Reagent in Nucleotide Synthesis via the Phosphoramidite Route. Design of New Effective Phosphitylating Reagents., Tetrahedron Lett., 2000, 41, 7535-7539.
  14. W. Dabkowski, I. Tworowska, E. Poniatowska, J. Michalski, F. Cramer, Novel Unique Activating Reagents in Synthesis of Biophosphates via Phosphoroamidite Route., Phosphorus, Sulfur and Silicon, 1999, 144-146, 109-112.
  15. W. Dabkowski, I. Tworowska, E. Poniatowska, J. Michalski, F. Cramer, New Phosphitylating Reagents Containing P-F Bond and Their Application in the Synthesis of P-Fluoro Nucleosidyl Phosphates, Thiophosphates and Selenophosphates, Nucleosides & Nucleotides, 1999, 18(6,7), 1247-1248.
  16. W. Dabkowski, I. Tworowska, New strategies for chemical synthesis of phosphorodithioates from 2'- or 3'- or 5'-thionucleosides, Nucleosides & Nucleotides, 1999 18(4, 5), 977-988.
  17. W. Dabkowski, M. Michalska, I. Tworowska, A Simple and Efficient Synthesis of Nucleotide containing 5’-S- or 3’-S-phosphorothioate Linkage., Nucleosides & Nucleotides, 1998, 9-11, 1635-1637.
  18. W. Dabkowski, I. Tworowska, J. Michalski, F. Cramer, Novel Unique Catalytic Activating Reagents in the Synthesis of Biophosphates via the phosphoramidite Route. Nucleosides & Nucleotides, 1998, 9-11, 1639-1644.
  19. W. Dabkowski, M. Michalska, I. Tworowska, Highly Efficient Synthesis of Phosphorodithioates Derived from 3’-Thiothymidine by Anhydro-ring Opening of 2,3’-Anhydro-5’-tritylthymidine with O,O-Disubstitued Phosphorothioic Acids., J. Chem. Soc., Chem. Commun., 1998, 427-428.
  20. W. Dabkowski, I. Tworowska, J. Michalski, F. Cramer, Trimethylchlorosilane: a novel activating reagent in nucleotide synthesis via the phosphoramidite route., J. Chem. Soc., Chem. Commun., 1997, 877-878.

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