Prof. Noah Isakov

Ben Gurion University of the Negev, Israel



1976-1981 Ph.D., The Weizmann Institute of Science, Rehovot, Israel

1974-1976 M.Sc., The Weizmann Institute of Science, Rehovot, Israel

1971-1974 B.Sc., Ben Gurion University of the Negev, Beer Sheba, Israel

Publications (Selected)

  1. Pandya, P., Pasvolsky, R., Babichev, B., Braiman, A., Witte, S., Altman, A. and Isakov, N. 2018. PICOT binding to the Polycomb group protein, EED, alters H3K27 methylation at the MYT1 PRC2 target gene. Biochem. Biophys. Res. Commun. 509:469-475, 2019.
  2. Nayak, S., Koven, W., Meiri, M., Khozin-Goldberg, I., Isakov, N., Zibdeh, M. and Zilberg, D. 2017. Dietary arachidonic acid affects immune function and fatty acid composition in cultured rabbitfish Siganus rivulatus. Fish Shellfish Immunol. 68:46-53.
  3. Isakov, N. 2016. DFTD: A contagious fatal cancer that threatens the Tasmanian devils. J. Clin. Cell. Immunol. 7:e118 (1-3).
  4. Sharon, G., Pimenta-Leibowitz, M., Vilchis, M. C. L., Isakov, N. and Zilberg, D. 2015. Controlled infection of Poecilia reticulata Peters (guppy) with Tetrahymena by immersion and intraperitoneal injection. J. Fish Dis. 38:67-74.
  5. Etzion, Y., Ozer, J., Ishay, Y., Sahar, G. and Isakov, N. 2014. PICOT as a dual regulator of cardiomyocyte hypertrophy and inotropy. J. Clin. Case Rep. 4: e1131.
  6. Gelkop, S., Weisman, B., Pulak, R.N., Zharhary, D. and Isakov, N. 2012. Development of unique antibodies directed against each of the six different phosphotyrosine residues within the T cell receptor CD3 chain. J. Immunol. Methods. 375:129-37.
  7. Ohayon, A., Golenser, J., Sinay, R., Tamir, A., Altman, A., Pollack, Y. and Isakov, N. 2010. PKCθ deficiency increases resistance of C57BL/6J mice to Plasmodium berghei infection-induced cerebral malaria. Infect. Immunity 78:4195-4205.
  8. Ohayon, A., Babichev, Y., Galperin, M., Altman, A. and Isakov, N. 2010. Widespread Expression of PICOT in Mouse and Human Tissues with Predominant Localization to Epithelium. 2010. J. Histochem. Cytochem. 58:799-806.
  9. Cohen, S., Braiman, A., Shubinsky, G., Ohayon, A., Altman, A. and Isakov, N. 2009. PKCO is required for hemostasis and positive regulation of thrombin-induced platelet aggregation and a-granule secretion. Biochem. Biophys. Res Commun. 385:22-27.
  10. Ohayon, A., Dong, G., Cohen, S., Galperin, M., Givoni, A., Moyal, K. and Isakov, N. 2008. PICOT: A Trx- and Grx-like protein in search of a function. The Open Enzyme Inhibition Journal. 1:48-51.
  11. Ohayon, A., Dong, G. and Isakov, N. 2007. Involvement of PKCØ in CD4+ T cell polarization and mouse resistance to cutaneous Leishmaniasis. In: ‘Lymphocyte Activation and Signal Transduction’. N. Isakov, (Ed), Transworld Research Network, Trivandrum, Kerala, India, pp. 221-238.
  12. Gelkop, S. Gish, J., Babichev, Y., Pawson, T. and Isakov, N. 2005. T cell activation-induced CrkII binding to the ZAP-70 protein tyrosine kinase is mediated by Lck-dependent phosphorylation of ZAP-70 tyrosine 315. J. Immunol. 175:8123-8132.

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