Department of Neurology
University of Texas Health Science Center at Houston,
2004-2008 Ph.D., Chosun
University, Protein Biochemistry
1999-2001 M.Sc., Jiwaji
1991-1994 B.S., Magadh
Shahnawaz M, Takahiko Tokuda, Masaaki Waragai, Nicolas Mendez, Ryotaro
Ishii, Claudia Trenkwalder, Brit Mollenhauer and Claudio Soto. Biochemical diagnosis
of Parkinson's disease by detection of α-synuclein misfolded aggregates in
cerebrospinal fluid. JAMA Neurology. 2016 Dec 5.
Salvadores N, Shahnawaz M, Scarpini E, Tagliavini F, Soto C. Detection of
Misfolded Aβ Oligomers for Sensitive Biochemical Diagnosis of Alzheimer's
Disease. Cell Reports. 2014 Mar 18.
Sharoar MG, Islam MI, Shahnawaz M, Shin SY, Park IS. Amyloid β binds
procaspase-9 to inhibit assembly of Apaf-1 apoptosome and intrinsic apoptosis
pathway. Biochim Biophys Acta. 2014 Apr; 1843(4): 685-93.
Shahnawaz M, Sharoar MG, Shin SY, Park IS. Wild-type, Flemish, and Dutch
amyloid-β exhibit different cytotoxicities depending on Aβ40 to Aβ42 interaction
time and concentration ratio. J Pept Sci. 2013 Sep; 19(9): 545-53.
Sharoar MG, Shahnawaz M, Islam MI, Ramasamy VS, Shin SY, Park IS. The
inhibitory effects of Escherichia coli maltose binding protein on β-amyloid
aggregation and cytotoxicity. Arch Biochem Biophys. 2013 Oct 1; 538(1): 41-8.
Sharoar MG, Thapa A, Shahnawaz M, Ramasamy VS, Woo ER, Shin SY, Park IS.
Keampferol-3 O-rhamnoside abrogates amyloid beta toxicity by modulating monomers
and remodeling oligomers and fibrils to non-toxic aggregates. J Biomed Sci.
2012 Dec 21; 19: 04.
Shahnawaz M, Soto Claudio. Microcin amyloid fibrils are a reservoir of
toxic oligomeric species. Journal of Biological Chemistry. 2012 Apr 6; 287(15):
Thapa A, Shahnawaz M, Karki P, Raj Dahal G, Golam Sharoar M, Yub Shin S,
Sup Lee J, Cho B, Park IS. Purification of inclusion body-forming peptides and
proteins in soluble form by fusion to Escherichia coli thermostable proteins.
Biotechniques. 2008 May; 44(6): 787-96.
Dahal GR, Karki P, Thapa A, Shahnawaz M, Shin SY, Lee JS, Cho B, Park IS.
Caspase-2 cleaves DNA fragmentation factor (DFF45)/inhibitor of caspase-activated
DNase (ICAD). Arch Biochem Biophys. 2007 Dec 1; 468(1): 134-9.
Shahnawaz M, Thapa A, Park IS. Stable activity of a deubiquitylating
enzyme (Usp2-cc) in the presence of high concentrations of urea and its
application to purify aggregation-prone peptides Biochem Biophys Res Commun.
2007 Aug 3; 359(3): 801-5.
Ashraf S, Singh PK, Yadav DK, Shahnawaz M, Mishra S, Sawant SV, Tuli R.
High level expression of surface glycoprotein of rabies virus in tobacco leaves
and its immunoprotective activity in mice. J Biotechnology. 2005 Sep 22;