Prof. Yuping Zhou

Eli Lilly and Company, USA

Research Scientist



2013 Ph.D., Bio-Analytical Chemistry, University of Massachusetts Amherst, USA

2008 M.S., Chemistry, Zhejiang University, Hangzhou, China

2006 B.S., Chemistry (Minor in German), Zhejiang University, Hangzhou, China,

Research Fields

Mass Spectrometry

Separation Science

Protein structure characterization

Publications (Selected)

  1. Zhou, Y. P. "The potential Biomedical Application of Cyclopeptides from Marine Natural Products" Curr. Org. Chem., 2014, 18, 918-924
  2. Borotto, N.; Weber, N.; Zhou, Y.P.; Vachet, R.W. "Label Scrambling During CID of Covalently Labeled Peptide Ions" J. Am. Soc. Mass Spectrom., 2014, 25, 1739-1746
  3. Zhou, Y. P.; Vachet, R.W. "Covalent Labeling with Isotopically Encoded Reagents for Faster Structural Analysis of Proteins by Mass Spectrometry" Anal. Chem., 2013, 85, 9664-9670
  4. Guo, C.; Zhou, Y. P.; Liu, P. Y.; Chai, Y. F.; Pan, Y. J. "Gas Phase Chemistry of Li+ with Amides: the observation of LiOH Loss in Mass Spectrometry" J. Am. Soc. Mass Spectrom., 2012, 23, 1191-1201
  5. Zhou, Y. P.; Vachet, R.W. "Diethylpyrocarbonate labeling for the structural analysis of proteins: label scrambling in solution and how to avoid it" J. Am. Soc. Mass Spectrom., 2012, 23, 899-907 (Cover Article)
  6. Zhou, Y. P.; Vachet, R.W. "Increased protein structural resolution from diethylpyrocarbonate-based covalent labeling and mass spectrometric detection" J. Am. Soc. Mass Spectrom., 2012, 23, 708-717
  7. Zhou, Y. P.; Dong, J.; Vachet, R. W. "Electron Transfer Dissociation of Modified Peptides and Proteins" Curr. Pharm. Biotechnol. 2011, 12, 1558-1567
  8. Hu, N.; Liu, P. Y.; Jiang, K. Z.; Zhou, Y. P.; Pan, Y. J. "Mechanism study of SO2 elimination from sulfonamides by negative electrospray ionization mass spectrometry" Rapid Commun. Mass Spectrom., 2008, 17, 2715-2722
  9. Zhou, Y. P.; Pan, Y. J.; Cao, X. J.; Wu, J.; Jiang, K. Z. "Gas-phase smiles rearrangement reactions of deprotonated 2-(4,6-dimethoxypyrimidin-2-ylsulfanyl)-N-phenylbenzamide and its derivatives in electrospray ionization mass spectrometry" J. Am. Soc. Mass Spectrom., 2007, 18 1813-1820

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