Prof. Devrishi Goswami

The SCRIPPS Research Institute

Jupiter, USA



2010 Ph.D., Max Planck Institute of Biophysics, Frankfurt, Germany

2004 M.Sc., Pondichery University, India, Biotechnology

Publications (Selected)

  1. Goswami D, Devarakonda S, Chalmers MJ, Pascal B, Spiegelman BM, Griffin PR (2013). Time window expansion for HDX analysis of an intrinsically disordered protein.J Am Soc Mass Spectrom Oct; 24(10): 1584-92.
  2. Landgraf RR*, Goswami D*, RajamohanF, Harris MS, Pascal BD, Chalmers MJ, Kurumbail R. Griffin PR (2013) Mechanism of activation of AMP activated protein kinase revealed by hydrogen/deuterium exchange mass spectrometry.StructureSep 24, PMID 24076403.
  3. Zhang Y,Goswami D, Wang D, Wang TS, Sen S, Magliery TJ, Griffin PR, Wang F and Schultz PG (2013) An Antibody with an Antiparallel Heterodimeric coiled Coil CDR3 Protein Fusion.Angew Chem Int Ed Engl(Accepted)
  4. Harms MJ, Eick GN,Goswami D, Colucci JK, Griffin PR, Ortlund EA, Thornton JW (2013) Biophysical mechanisms for large-effect mutations in the evolution of steroid hormone receptors.PNASU S A. Jul 9;110(28):11475-80.
  5. Kumar R,Moure CM, Khan SH, Callaway C, Grimm S,Goswami D, Griffin PR, and Edwards DP (2013)Regulation of the structurally dynamic amino-terminal domain of progesterone receptor by protein induced folding.J Biol ChemAug 30. [Epub ahead of print]
  6. Chang MR,Goswami D, Mercer BA, Griffin PR (2012) Therapeutic potential of RORγ modulators in the treatment of human disease.J. of exp. Pharmacology.:4, 141-148.
  7. Pascal BD, Willis S, Lauer JL, Landgraf RR, West GM, Marciano D, Novick S,Goswami D, Chalmers MJ, Griffin PR. (2012). HDX Workbench: Software for the Analysis of H/D Exchange MS Data.J Am Soc Mass Spectrom. Oct;24(10):1584-92.
  8. Khan SH, Awasthi S, Guo C,Goswami D, Ling J, Griffin PR, Simons SS Jr, Kumar R. (2012). Binding of the N-terminal region of coactivator TIF2 to the intrinsically disordered AF1 domain of the glucocorticoid receptor is accompanied by conformational reorganizations.J Biol Chem.Dec 28;287(53):44546-60.
  9. Goswami D, Kaur J, Surade S, Grell E and Michel H. (2012) Heterologous production, functional and thermodynamic characterization of cation diffusion facilitator (CDF) transporters of mesophilic and hyperthermophilic origin.Biol Chem. Jul;393(7):617-29.
  10. Bajaj K, Dewan PC, Chakrabarti P,Goswami D, Barua B, Baliga C, Varadarajan R. (2008). Structural correlates of the temperature sensitive phenotype derived from saturation mutagenesis studies of CcdB. Biochemistry 47(49):12964-73.