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Biography

Dr. Enming Joseph Su

University of Michigan, USA


Email: bartl@chem.utah.edu


Qualifications
1998  Ph.D., Pathology, University of Washington, USA

1991  B.Sc., Biology, Oral Roberts University, USA


Publications(Selected)
  1. Su EJ, Geyer M, Wahl M, Mann K, Ginsburg D, Brohmann H, Petersen KU, Lawrence DA. The thrombomodulin analog Solulin promotes reperfusion and reduces infarct volume in a thrombotic stroke model.J Thromb Haemost. 2011 Jun;9(6):1174-82. PMCID: PMC3111949
  2. Su EJ, Fredriksson L, Schielke GP, Eriksson U, Lawrence DA. Tissue plasminogen activator-mediated PDGF signaling and neurovascular coupling in stroke. J Thromb Haemost, 2009 Jul; 7 Suppl 1:155-8. PMCID: PMC291222
  3. Hyman MC, Petrovic-Djergovic D, Visovatti SH, Liao H, Yanamadala S, Bouïs D, Su EJ, Lawrence DA, Broekman MJ, Marcus AJ, Pinsky DJ.Self-regulation of inflammatory cell trafficking in mice by the leukocyte surface apyrase CD39.J Clin Invest. 2009;119(5):1136-49. PMCID: PMC2673847
  4. Su EJ, Fredriksson L, Geyer M, Folestad E, Cale J, Andrae J, Gao Y, Pietras K, Mann K, Yepes M, Strickland DK, Betsholtz C, Eriksson U, Lawrence DA. Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain integrity during ischemic stroke. Nat. Med. 2008;14:731-737. (see commentaries Nat. Med, 2008; 14: 712-713; Science Signaling (Editors' Choice) 2008; 1(28), ec255 Ed (doi:0.1126/scisignal.128ec255); Nature Reviews Drug Discovery, 2008; 7, 643 (doi:10.1038/nrd2642); SciBX: Science–Business eXchange, 2008; 1(23): 1-4.) PMCID: PMC2811427
  5. Stefansson S, Su EJ, Ishigami S, Cale JM, Gao Y, Gorlatova N, Lawrence DA. The contributions of integrin affinity and intergri-cytoskeletal engagement in endothelial and smooth muscle cell adhesion to vitronectin. J Bio Chem, 2007; 282:15679-15689.
  6. Leik CE, Su EJ, Nambi P, Crandall DL, Lawrence D.A. Effect of Pharmacologic PAI-1 Inhibition on Cell Motility and Tumor Angiogenesis. J Thromb Haemost. 4:2710-2715, 2006.
  7. Cao C, Lawrence DA, Li Y, Von ArnimCA, Herz J, Su EJ, Makarova A, Hyman BT, Strickland DK, Zhang L; Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration. EMBO J. 2006 May 3;25(9):1860-70.
  8. Su EJ, Cioffi CL,Stefansson S, Mittereder N,Garay M, Hreniuk D, Liau G. Gene Therapy Vector-mediated Expression of Insulin-like Growth Factors Protects Cardiomyocytes from Apoptosis and Enhances Neovascularization. Am J Physiol Heart Circ Physiol 2003 Apr 284(4):H1429-40.
  9. Ancellin N, Colmont C, Su J, Li Q, Mittereder N, Chae SS, Stefansson S, Liau G, Hla T. Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation. J Biol Chem 2002 Feb 22; 277(8):6667-75.
  10. Liau G, Su EJ, Dixon KD. Clinical efforts to modulate angiogenesis in the adult: gene therapy versus conventional approaches. Drug Discov Today 2001 Jul 1; 6(13): 689-697.
  11. Su EJ, Stevenson SC, Rollence M, Marshall-Neff J, Liau G: A genetically modified adenoviral vector exhibits enhanced gene transfer of human smooth muscle cells. J Vasc Res 2001 Sep-Oct; 38(5): 471-8.
  12. Su EJ, Lombardi DM, Wiener J, Daemen MJAP, Reidy MA, Schwartz SM: Mitogenic effect of angiotensin II on rat carotid arteries and type II or III mesenteric microvessels, but not type I mesenteric microvessels, is mediated by endogenous basic fibroblast growth factor. Circ Res. 1998; 82:321-327.
  13. Su EJ, Lombardi DM, Siegal J, Schwartz SM: Angiotensin II indues smooth muscle replication in the vessel wall independent of blood pressure. Hypertension. 1998; 31(6): 1331-7.
  14. deBlois D, Lombardi DM, Su EJ, Clowes AW, Schwartz SM, Giachelli CM: Angiotensin II induction of osteopontin expression and DNA replication in rat arteries. Hypertension. 1996; 28:1055-1063.
  15. deBlois D, Schwartz SM, Van Kleef EM, Su EJ, Griffin KA, Bidani AK, Daemen MJAP, Lombardi DM: Chronic alpha1-adrenoreceptor stimulation increases DNA synthesis in rat arterial wall:modulation of responsiveness after vascular injury. Arteriosclerosis, Thrombosis, and Vascular Biology 1996; 16:1122-1129.