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Biography
C. Cameron

Dr. C. Cameron Yin

Department of Hematopathology

University of Texas MD Anderson Cancer Center, USA


Email: cyin@mdanderson.org


Qualifications

2004-2005 Fellowship, Molecular Genetic Pathology, UT MD Anderson Cancer Center, USA

2003-2004 Fellowship, Hematopathology, UT MD Anderson Cancer Center, USA

1999-2003 Residency, Anatomic and Clinical Pathology, Kansas University Medical Center, USA

1998 Ph.D., Pathology, University of Wisconsin, USA

1990 M.D., Medicine, Beijing Medical University, China


Publications(Selected)

  1. Jones D, Thomas D, Yin CC, O'Brien S, Cortes JE, Jabbour E, Breeden M, Giles FJ, Zhao W, Kantarjian HM. Kinase domain point mutations in Ph+ acute lymphoblastic leukemia (ALL) emerge following therapy with BCR-ABL kinase inhibitors. Cancer 2008;113(5):985-94.
  2. Huh YO, Lin KI, Vega F, Schlette E, Yin CC, Keating MJ, Luthra R, Medeiros LJ, Abruzzo LV. Myc translocation in chronic lymphocytic leukemia is associated with increased prolymphocytes and a poor prognosis. Br J Haematol 2008;142(1):36-44.
  3. Yin CC, Jones D, Cortes J, Kantarjian H, Medeiros LJ, Bueso-Ramos CE. Type B CBFb/MYH11 fusion transcript in de novo myeloid blast phase of chronic myeloid leukemia: Correlation with nuclear and cytoplasmic localization of the fusion protein. Clin Leukemia 2008;2(4):257-60.
  4. Lin P, Lenon PA, Yin CC, Abruzzo LV. Chronic myeloid leukemia in blast phase associated with t(3;8)(q26;q24). Cancer Genetics and Cytogenetics 2009; 193(2):119-22.
  5. Zhang S, Mao Y, Huang J, Ma T, Zhang L, Zhu X, Zheng J, Wu L, Yin CC, Qiu X. Immunoglobulin gene locus events in epithelial cells of lactating mouse mammary glands. Cell Mol Life Sci 2009;67(6):985-94.
  6. Yin CC, Lin KI, Ketterling RP, Knudson RA, Medeiros LJ, Barron LL, Huh YO, Luthra R, Keating MJ, Abruzzo LV. Chronic lymphocytic leukemia with t(2;14)(p16;q32) involves the BCL11A and IgH genes, and is associated withth atypical morphology, unmutated IgVH genes, and an aggressive clinical course. Am J Clin Pathol 2009;131(5):663-70.
  7. Yin CC, Abruzzo LV, Qiu X, Apostolidou JE, Cortes JE, Medeiros LJ, Lu G. Del(15q) is a recurrent "minor route" cytogenetic abnormality in the clonal evolution of chronic myelogenous leukemia. Cancer Genet Cytogenet 2009;192(1):18-23.
  8. Lu G, Yin CC, Medeiros LJ, Abruzzo LV. Deletion 15q as the sole abnormality in acute myeloid leukemia: Report of three cases and review of the literature. Cancer Genet Cytogenet 2009;188(2):118-23.
  9. Zhu X, Wu L, Zhang L, Hao P, Zheng J, Liu Y, Li W, Zhang Y, Zhou C, Zhang Y, Yin CC, Qiu X. Distinct regulatory mechanism of immunoglobulin gene transcription in epithelial cancer cells. Cell Mol Immunol, 2010;7(4):279-86.
  10. Yin CC, Cortes J, Galbincea J, Reddy N, Breeden M, Jabbour E, Luthra R, Jones D. Rapid clonal shifts in response to kinase inhibitor therapy in chronic myeloid leukemia are identified by quantitation mutation assays. Cancer Science. 2010;101(9):2005-10.
  11. Konoplev S, Lin P, Qiu X, Medeiros LJ, Yin CC. Clonal relationship of extranodal marginal zone lymphomas of mucosa-associated tissue involving different sites. Am J Clin Pathol 2010;134(1):112-8.
  12. Liang M, Han X, Vadhan-Raj S, Nguyen M, Zhang YH, Fernandez M, Drakos E, Konoplev SN, Yin CC, Miranda RN, McDonnell TJ, Medeiros LJ, Bueso-Ramos CE. HDM4 is overexpressed in mantle cell lymphoma and its inhibition induces p21 expression and apoptosis. Mod Pathol 2010;23(3):381-91.
  13. Li T, Medeiros LJ, Lin P, Yin H, Littlejohn M, Im W, Lenon PA, Hu P, Jorgensen LJ, Liang M, Guo H, Yin CC. Immunohistochemical profile and FISH analysis of diffuse large B-cell lymphoma in northern China. Arch Pathol Lab Med 2010;134(5):759-65.
  14. Talwalkar SS, Yin CC, Naeem RC, Strong LC, Abruzzo LV. Myelodysplastic syndromes arising in patients with Li-Fraumeni synderome. Arch Pathol Lab Med 2010;134(7):1010-5.
  15. Cui W, Bueso-Ramos CE, Yin CC, Sun J, Chen S, Muddasani R, Lu G. Trisomy 14 as a sole chromosome abnormality is associated with older age, a heterogenous group of myeloid neoplasms with dysplasia and a wide spectrum of disease progression. J Biomed Biotechnol 2010;2010:365318-24.
  16. Yin CC, Medeiros LJ, Bueso-Ramos CE. Recent advances in the diagnosis and classification of myeloid neoplasms. Int J Lab Hematol 2010;32(5):461-476.
  17. Sun J, Yin CC, Cui W, Chen SS, Medeiros LJ, Lu G. Chromosome 20q deletion - a recurrent cytogenetic abnormality in patients with chronic myelogenous leukemia in remission. Am J Clin Pathol 2011;135(3):391-7.
  18. Gurevich I, Luthra R, Konoplev SN, Yin CC, Medeiros LJ, Lin P. Refractory anemia with ring sideroblasts associated with marked thrombocytosis: a mixed group with a spectrum of morphologic findings. Am J Clin Pathol 2011;135(3):398-403.
  19. Barakat FH, Luthra R, Yin CC, Barkoh BA, Hai S, Jamil W, Ghakta Y, Chen S, Medeiros LJ, Zuo Z. Detection of nucleophosmin 1 mutations by quantitative real-time polymerase chain reaction versus capillary electrophoresis: a comparative study. Arch Pathol Lab Med 2011;135(8):994-1000.
  20. Hoehn D, Bala KK, Fan W, Yin CC. Parinaud oculoglandular syndrome as a prominent presenting feature of Kikuchi-Fujimoto disease. N Am J Med Sci 2011;4(2):96-9.
  21. Li S, Medeiros LJ, Fayad L, Lennon PA, Yin CC, Lin P. “Double hit” high grade B-cell lymphomas with MYC and BCL2 rerrangements: a clinically aggressive disease with heterogeneous histologic features and outcome. Mod Pathol 2012;25(1):145-56.
  22. Hoehn D, Yin CC, Chen L, Sheridan G, Wenig BM. Diagnosing hypocellular collagenized spindle cell squamous carcinoma of the head and neck: A rare subtype with misleading histologic features. N Am J Med Sci 2012;5(1):9-12.
  23. Bai B, Zuo Z, Cheong SH, Vo B, Harper E, Lovshe D, Yang S, Yin CC. Novel chromosomal aberration as evidence of clonal evolution in a case of relapsed acute myeloid leukemia. N Am J Med Sci 2012;5(1):48-50.
  24. Kanagal-Shamanna R, Bueso-Ramos CE, Barkoh B, Lu G, Wang S, Garcia-Manero G, Vadhan-Raj S, Hoehn D, Medeiros LJ, Yin CC. i(17q) defines an aggressive myelodysplastic/myeproliferative neoplasm withTP53 Arg72, wild type NPM1 and high risk of leukemic transformation. Cancer 2011 [Epub ahead of print].
  25. Jaso J, Chen L, Li S, Lin P, Chen W, Miranda R, Konoplev S, Medeiros LJ, Yin CC. CD5-positive MALT lymphoma: a clinicopathologic study of 14 cases. Hum Pathol. In Press.
  26. Warren M, Luthra R, Yin CC, Ravandi F, Cortes JE, Kantarjian HM, Medeiros LJ, Zuo Z. Clinical impact of change of FLT3 mutation status in acute myeloid leukemia patients. Mod Pathol. In Press.
  27. Li S, Yin CC, Medeiros LJ, Bueso-Ramos C, Lu G, Lin P. Myelodysplastic syndrome/acute myeloid leukemia with t(3;21)(q26;q22) are commonly therapy related diseases associated with poor outcome. Am J Clin Pathol. In Press.
  28. Ohanian M, Laventaki V, Verstovsek S, Estrov Z, Lin P, Yin CC, Kantarjian H, Huh Y, Ravandi F. Transformation of post-polycythemic myelofibrosis into acute lymphoblastic leukemia, a rare entity. Leuk Lymphoma. In Press.