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Biography

Prof. Jacques E. Nör

University of Michigan, USA


Email: jenor@umich.edu


Qualifications

2001 Ph.D., Cancer Cell Biology, Dental School, University of Michigan
1994 M.Sc., Pediatric Dentistry, Dental School, University of Michigan


Publications (Selected)

  1. Zeitlin BD, Nör JE. Small-molecule inhibitors reveal a new function for Bcl-2 as a proangiogenic signaling molecule. Curr Top Microbiol Immunol 348:115-37, 2011.
  2. Krishnamurthy S, Nör JE.Head and neck cancer stem cells.J Dent Res2011 Sep 20. [Epub ahead of print]
  3. Wang J, Chen J, Zhang K, Zhao Y, Nör JE, Wu J. TGF-β1 regulates the invasive and metastatic potential of mucoepidermoid carcinoma cells.J Oral Pathol Med. 2011 Jun 21. [Epub ahead of print]
  4. Tarquinio S, Zhang Z, Neiva K, Polverini PJ, Nör JE. Endothelial cell Bcl-2 and lymph node metastasis in patients with oral squamous cell carcinoma.J Oral Pathol Med2011 Sep 21. [Epub ahead of print]
  5. Campos M, Neiva K, Meyers K, Krishnamurthy S, Nör JE.Endothelial derived factors inhibit anoikis of head and neck cancer stem cells.Oral Oncol2011 Oct 17. [Epub ahead of print].
  6. Zhang Z, Sant’ana M, Nör JE.The biology of head and neck cancer stem cells. Oral Oncol(In press).
  7. Conde MC, Nedel F, Campos VF, Smith AJ, Nör JE, Demarco FF, Tarquinio S.Odontoblastic RNA Stability in Different temperature based protocols for Tooth Storage. Int Endod J(In press).
  8. Chokechanachaisakul U, Kaneko T, Yamanaka Y, Kaneko R, Katsube K, Kobayashi H, Nör JE, Okiji T, Suda H. Gene expression analysis of resident macrophages in lipopolysaccharide-stimulated rat molar pulp. J Endod 37:1258-63, 2011.
  9. Casagrande L, Cordeiro MM, Nör SA, Nör JE.Dental Pulp Stem Cells in Regenerative Dentistry. Odontology 99:1-7, 2011.
  10. Kaneko T, Okiji T, Kaneko R, Suda H, Nör JE. Laser-capture microdissection for Factor VIII-expressing endothelial cells in cancer tissues. Methods Mol Biol 755:395-403, 2011.
  11. Sakai VT, Cordeiro MM, Dong Z, Zhang Z, Zeitlin BD, Nör JE.Tooth Slice/Scaffold Model of Dental Pulp Tissue Engineering. Adv Dent Res 23:325-332, 2011.
  12. Kim JK, Baker J, Nör JE, Hill EE. mTor Plays an Important Role in Odontoblast Differentiation. J Endod 37:1081-1085, 2011.
  13. Demarco FF, Conde MCM, Cavalcanti B, Casagrande L, Sakai V, Nör JE.Dental pulp tissue engineering. Braz Dent J 22:3-13, 2011.
  14. Cavalcanti BN, Campos MS, Nör JE. Stem cells in health and disease. Rev Assoc Paul Cirdent 65:71-4, 2011.
  15. ChokechanachaisakulU, KanekoT, OkijiT, KanekoR, Suda H, Nör JE. Laser Capture Microdissection in Dentistry. Int J Dent 2011 Jan 13. [Epub ahead of print]
  16. Morelli T, Neiva R, Nevins ML, McGuire MK, Scheyer ET, Oh TJ, Braun TM, Nör JE, Bates D, Giannobile WV. Angiogenic Markers and Healing of Living Cellular Constructs.J Dent Res 90:456-62, 2011.
  17. Hegen A, Blois A, Tiron CE, Hellesøy M, Micklem DR, Nör JE, Akslen LA, Lorens JB. Efficientin vivovascularization of tissue engineering scaffolds. J Tissue Engin Regen Med5(4):e52-62, 2011.
  18. Rosa V, Botero TM, Nör JE. Regenerative endodontics in light of the stem cell paradigm. Int Dent J 61 (Suppl.1):23-28, 2011.
  19. Nedel F, Soki FN, Conde MC, Zeitlin BD, Tarquinio SB, Nör JE, Seixas FK, Demarco FF. Comparative analysis of two colorimetric assays in dental pulp cell density. Int Endod J44:59-64, 2011.
  20. Zhang R, Cooper P, Smith G, Nör JE, Smith AJ. Angiogenic activity of dentin matrix components”. J Endod 37:26-30, 2011.
  21. Telles PD, Machado MA, Sakai VT, Nör JE.Pulp tissue from primary teeth: new source of stem cells. J Appl Oral Sci 19:189-94, 2011.
  22. KrishnamurthyS, DongZ, VodopyanovD, ImaiA, HelmanJI, PrinceME, WichaMS, Nör JE. Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells. Cancer Res 70:9969-9978, 2010.
  23. Zhang Z, Neiva K, Lingen MW, Ellis LM, Nör JE. VEGF-dependent tumor angiogenesis requires the inverse and reciprocal regulation of VEGFR1 and VEGFR2. Cell Death Diff 17:499-512, 2010.
  24. Zeitlin BD, Spalding AC, Campos MS, Ashimori N, Dong Z, Wang S, Lawrence TS, Nör JE. Metronomic small molecule inhibitor of Bcl-2 is anti-angiogenic and potentiates the anti-tumor effect of ionizing radiation. Int J Radia Oncol 78:879-887,2010(Highlights section).
  25. Giordano RJ, Cardó-Vila M, Salameh A, Anobom CD, Zeitlin BD, Hawke DH, Valente AP, Almeida FC, Nör JE, Sidman RL, Pasqualini R, Arap W.From combinatorial peptide selection to drug prototype (I): Targeting the vascular endothelial growth factor receptor pathway. Proc Natl Acad Sci USA 107:5112-5117, 2010.
  26. Casagrande L, Demarco F, Zhang Z, Araujo FB, Shi S, Nör JE. Dentin-derived BMP2 and odontoblastic differentiation of SHED. J Dent Res 89:603-608, 2010 (Journal Cover).
  27. Sakai VT, Zhang Z, Dong Z, Neiva K, Machado M, Shi S, Santos C, Nör JE. SHED Differentiate Into Functional Odontoblasts and Endothelium. J Dent Res 89:791-796, 2010.
  28. Demarco F, Casagrande L, Zhang Z, Dong Z, Tarquinio S, Zeitlin B, Shi S,Smith A, Nör JE.The effects of morphogen and scaffold porogen on the differentiation of dental pulp stem cells. J Endod36:1805-1811, 2010 (Journal cover).
  29. BoteroTM, SonJS, VodopyanovD, ShelburneCE, Nör JE.MAPK signaling is required for LPS-induced VEGF in pulp stem cells. J Dent Res 89:264-269, 2010 (Journal cover).
  30. Liu J, Jin T, Chang S, Czajka-Jakubowska A, Zhang Z, Nör JE, Clarkson BH. The effect of novel fluorapatite (FA) surfaces on osteoblast-like cell adhesion, growth and mineralization. Tissue Engineering Part A 16:2977-2986, 2010.