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Biography
Prof. Peng Lee

Prof. Peng Lee

School of Medicine

New York University, USA


Email: peng.lee@nyumc.org


Qualifications

1995 Ph.D., Downstate Medical Center, State University of New York
1989 M.D., School of Medicine, Peking University


Publications (Selected)

  1. Berger AD, Satagopan J, Lee P, Taneja SS, Osman I. Racial differences in the clinicopathological features of prostate cancer: Significant changes between patients treated in the 1990’s and 2000’s (2006) Urology 67(1):120-124.
  2. Fischer I, Wieczorek R, Sidhu GS, Pei ZH, West AB, Lee P*. Myxoid lipoadenoma of parathyroid gland: A case report and literature review (2006) Annals of Diagnostic Pathology 10(5):294-6.
  3. Douglas DA, Zhong H, Ro JY, Oddoux C, Berger AD, Pincus MR, Satagopan JM, Gerald WL, Scher HI, Lee P*, Osman I. Racial difference in somatic mutations of epidermal growth factor receptor in prostate cancer. Frontiers in Bioscience 11:2518-25.
  4. Gao S, Wang H, Zhang F, Lee P, Li CH and Wang ZX Androgen Receptor and Prostate Apoptosis Response Factor-4 Target the c-FLIP Gene to Determine Survival and Apoptosis in the Prostate Gland (2006) Journal of Molecular Endocrinology 36(3):463-83.
  5. Zhou L, Wu H, Lee P, Wang ZX. The role of androgen receptor cofactor p44 in controlling proliferation of prostate epithelial cells (2006) Journal of Molecular Endocrinology 37(2):283-300.
  6. Osman I, Dai J, Mikhail M, Navarro D, Taneja SS, Lee P, Christos P, Shen R, Nanus DM. Loss of neutral endopeptidase and activation of protein kinase B (Akt) is associated with prostate cancer progression (2006) Cancer 107(11):2628-36.
  7. Liang JJ, Wang ZX, Chiriboga L, Greco MA, Shapiro E, Huang HY, Yang XM, Huang JT, Peng Y, Melamed J, Lee P*. Androgen receptor coactivator p44 and PRMT5 in the developing testis and testicular tumors (2007) Journal of Urology 177: 1918.
  8. Kong X, ZhaoY, Ksionsk M, Walden PD, Bosland MC, Lee P, Melamed J. Radiographic Determination of tissue thickness in paraffin blocks: application to the construction of tissue microarrays. (2007) Applied Immunohistochemistry & Molecular Morphology 15:108–112.
  9. Wang T, Zhang X, Obijuru L, Laser J, Aris A, Lee P, Mittal K, Soteropoulos P, Wei JJ. A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas. (2007) Genes, Chromosomes and Cancer 46(4):336-47.
  10. Peng Y, Chiriboga L, Pei Z, Wang Z and Lee P*. Androgen receptor coactivator ARA70 and ARA70 isoform-specific antibodies: new tools for studies of expression and immunohisto-chemical localization (2008) Applied Immunohistochemistry & Molecular Morphology 16(1):7-12.
  11. Peng Y, Li C, Chen F, Ligr M, Wei JJ, Wang Z, Melamed J, Pagano M, Garabedian M, Lee P*. Stimulation of prostate growth and invasion by androgen receptor cofactor ARA70 (2008) American Journal of Pathology 172(1):225-35.
  12. Peng Y, Chen F, Melamed J, Chiriboga L, Wei J, Kong X, McLeod M, Li Y, Li CX, Feng A, Garabedian MJ, Wang Z, Roeder RG, Lee P*. Distinct nuclear and cytoplasmic functions of androgen receptor cofactor p44 and association with androgen-independent prostate cancer (2008) Proceedings of the National Academy of Sciences of the United States of America. 105(13):5236-41.
  13. Cai CQ, Peng Y, Buckley MT, Wei J, Chen F, Liebes L, Gerald WL, Pincus MR, Osman I, Lee P*. EGFR inhibitor reduced the enhanced growth and invasion by EGFR mutation in prostate cancer. (2008) Oncogene 27(22):3201-10.
  14. Peng Y, Laser J, Ye H, Peng L, Zavadil J, Melamed J, Soteropoulos P, Mittal K, Lee P*, Wei JJ. Repression of High-mobility group A2 by let-7 miRNAs using uterine leiomyoma and prostate cancer as models (2008) Molecular Cancer Research 6(4):663-73.
  15. Dash A, Lee P, Zhou Q, Berger A, Jean-Gilles J, Satagopan J, Reuter V, Gerald W, Scher HI, Eastham J, Osman I, The impact of socioeconomic factors on prostate cancer outcomes in black patients treated with surgery (2008) Urology 72(3):641-6.
  16. Shapiro E, Huang HY, Ruoff R., Lee P, Tanese N, and Logan S.K. Regulation of the HP1 family in prostate development and cancer. (2008) Journal of Urology 179(6):2435-9.
  17. Li Y, Li CX, Chen F, Ligr M, Pearce P, Ye H, Kim J, , Yi P, Perle MA, Liu J, Wang Z, Melamed J, Garabedian M, Walden P, Lee P*. Decrease in stromal androgen receptor associates with androgen-independent disease and promotes prostate cancer cell proliferation and invasion (2008) Journal of Cellular and Molecular Medicine 12(6b):2790-2798.
  18. Peng L, Wen Y, Han Y, Wei A, Shi G, Chiriboga L, Mizuguchi M, Yee H, Melamed J, Lee P, Hernando E, Mittal K, Wei JJ Expression of Insulin-Like Growth Factors (IGFs) and IGF signaling: Molecular Complexity in Uterine Leiomyomas. (2009) Fertility and Sterility 91(6): 2664-2675.
  19. Shi G, Perle MA, Mittal K, Chen H, Zou X, Hernando E, Lee P*, Wei JJ Let-7 repression leads to HMGA2 overexpression in uterine leiomyosarcoma (2009) Journal of Cellular and Molecular Medicine 13(9b): 3898–3905.
  20. Ye H, Li Y, Melamed J, Pearce P, Wei J, Chiriboga L, Wang Z, Osman I, Lee P* Stromal anti-apoptotic androgen receptor target gene c-FLIP in prostate cancer (2009) Journal of Urology 181(2):872-7.
  21. Wang L, Berger AD, Zou X, Twiss C, Peng Y, Li Y, Chiu J, Satagopan J, Wilton A, Gerald W, Basch R, Osman I, Lee P* Increased expression of histone deacetylaces (HDACs) and inhibition of prostate cancer growth and invasion by HDAC inhibitor SAHA (2009) American Journal of Translational Research 1(1):62-71.
  22. Laser G, Lee P, Wei JJ Cellular senescence in uterine leiomyoma (2010) Fertility and Sterility 93:2020-2026.
  23. Newman K, Stahl-Herz J, Kabiawu O, Newman E, Wieczorek R, Wang B, Pei Z, Lee P, Xu R Pancreatic Carcinoma with Multilineage (Acinar, Neuroendocrine, and Ductal) Differentiation. International Journal of Clinical and Experimental Pathology 2(6),602-607; 2009.
  24. Guo C, Yang G, Khun K, Kong X, Levy D, Lee P*, Melamed J Activation of Stat3 in renal tumors. (2009) American Journal of Translational Research 1(3): 283–290.
  25. Li Y, Wang L, Zhang M, Melamed J, Liu X, Reiter R, Wei J, Peng Y, Zou X, Pellicer A, Garabedian MJ, Ferrari A, Lee P* LEF1 in androgen-independent prostate cancer: regulation of androgen receptor expression, prostate cancer growth and invasion (2009) Cancer Research 69(8):3332-3338.
  26. Huang J, Lee P, Mikami Y, Melamed J Dysplastic (“in-situ”) Lesions in multofocal renal oncocytomas(oncocytosis). International Journal of Clinical and Experimental Pathology 2(6), 583-587; 2009.
  27. Wei J, Wu J, Luan C, Yeldandi A, Lee P, Keh P, Liu J, HMGA2: A potential biomarker compliment to p53 for detection of early Stage of high grade papillary serous carcinoma in fallopian tubes American Journal of Surgical Pathology 34(1):18-26.
  28. Peng Y, Li Y, Lan L, Zou X, Wang J, Singh B, Xu R, Chiriboga L, Zhang X, Zhou J, Garabedian MJ, Schneider RJ, Wang Z, Lee P* Androgen receptor coactivator p44/Mep50 in breast cancer growth and invasion (2010) Journal of Cellular and Molecular Medicine 14(12):2780-2789.
  29. Ligr M, Li Y, Zou X, Melamed J, Peng Y, Ostrer H, Daniels D, Wang W, Pagano M, Wang Z, Garabedian MJ, Lee P* Tumor suppressor function of androgen receptor coactivator ARA70 in prostate cancer (2010) American Journal of Pathology 176(4): 1891–1900.
  30. Mahajan A, Liu Z, Gellert L, Zou X, Yang G, Yang X, Lee P, Wei J HMGA2: a biomarker significantly overexpressed in high-grade ovarian serous carcinoma. (2010) Modern Pathology 23(5):673-81.
  31. Monaco ME, Creighton CJ, Lee P, Zou X, Topham MK, Stafforini DM Expression of long-chain fatty acyl-CoA synthetase 4 in breast and prostate cancer is associated with sex steroid hormone insensitivity Translational Oncology 3(2):91-98.
  32. Pan L, Peng L, Jerome S, Prieto V, Osman I, Lee P* Novel PRKAR1A Gene Mutations in Carney Complex (2010) International Journal of Clinical and Experimental Pathology 3(5): 545–548.
  33. Pei AY, Oberdorf WE, Nossa CW, Agarwal A, Chokshi P, Gerz EA, Jin Z, Lee P, Yang L, Poles M, Brown SB, Sotero S, DeSantis T, Brodie E, Nelson K, Pei Z. Diversity of 16S rRNA genes within individual prokaryotic genomes (2010) Applied and Environmental Microbiology 76(12):3886-3897.
  34. Wu XY, Chen F, Sahin A, Albarracin C, Singh B, Xu R, Wei JJ, Schneider RJ, Cowin P, Lee P* Distinct expression and function of androgen receptor coactivator ARA70α and ARA70 in breast development and cancer Breast Cancer Research and Treatment 128(2):391-400.
  35. Rose AE, Satagopan JM, Oddoux C, Zhou Q, Yu JZ, Dash A, Jean‐Gilles J, Gerald W, Lee P*, Osman I Copy number and gene expression differences between African American and Caucasian American prostate cancer. (2010) Journal of Translational Medicine 8:70.
  36. Zavadil J, Ye H, Liu Z, Wu J, Lee P, Hernando E, Soteropoulos P, Torune GA, Wei J Profiling and functional analyses of microRNAs and their target gene products in human uterine leiomyomas. (2010) PLos One 5(8):e12362.
  37. Wu JJ, Liu Z, Shao C, Gong Y, Hernando E, Lee P, Narita M, Muller W, Liu J, Wei J HMGA2 overexpression induced ovarian surface epithelial transformation resembles high grade serous carcinoma through regulation of EMT genes (2011) Cancer Research 71(2):349-359.
  38. Wei J, Wu X, Peng Y, Olca B, Shi G, Yang X, Zou X, Melamed J, Ouyang J, Hernando E, Pellicer A, Rhim J, Osman I, Lee P* Regulation of HMGA1 expression by microRNA296 affects prostate cancer growth and invasion (2011) Clinical Cancer Research 17(6):1297-1305.
  39. Wu X, Daniels G, Hatcher D, Kun X, Li Y, Huang H, Shapiro E, Chiriboga L, Logan S, Greco MA, Grishina and Lee P* Lef1 identifies androgen independent epithelium in the developing prostate (2011) Molecular Endocrinology 25(6):1018-1026.
  40. Jain S, Singhal S, Francis F, Hajdu C, Wang J, Suriawinata A, Wang Y, Zhang M, Weinshel EH, Francois F, Pei Z, Lee P, Xu R. Overexpression of Transcription Intermediary Factor 1 Gamma (TIF1γ) Is Involved in Early Stage of Colorectal Carcinogenesis and Associated with Advanced Stage Colorectal Adenocarcinoma. (2011) World Journal of Gastroenterology.
  41. Lee L, Zhou F, Simms A, Wieczorek R, Fang Y, Subietas-Mayol A, Wang B, Heller P, Huang H, Pei Z, Osman I, Meehan S, Lee P* Metastatic balloon cell malignant melanoma: a case report and literature review International Journal of Clinical and Experimental Pathology 4(3): 315–321.