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Biography
4

Prof. Yurov Yuri Boris

Russian Academy of Medical Sciences, Russia
Professor


Email: y_yurov@yahoo.com


Qualifications

2011 Director, Russian Academy of Medical Sciences, Laboratory of Cytogenetics
1987  Senior Scientist, Russian Academy of Medical Science, National Research Center of Mental Health
1974  Professional Education, Moscow State University

Publications (Selected)

  1. Vorsanova SG, Yurov YB, Kolotii AD, Soloviev IV. FISH analysis of replication and transcription of chromosome X loci: new approach for genetic analysis of Rett syndrome. Brain Dev 2001 Dec;23 Suppl 1:S191-5.
  2. Soloviev IV, Yurov YB, Vorsanova SG, Fayet F, Roizes G, Malet P.
  3. Prenatal diagnosis of trisomy 21 using interphase fluorescence in situ hybridization of post-replicated cells with site-specific cosmid and cosmid contig probes. Prenat Diagn 1995 Mar;15(3):237-48.
  4. Yurov YB. Rate of DNA replication fork movement within a single mammalian cell. J Mol Biol 1980 Jan 25;136(3):339-42.
  5. Yurov YB. Do clusters of replication units in the mammalian cells exist? Exp Cell Res 1979 Oct 15;123(2):369-74.
  6. Yurov YB. The rate of fork movement during DNA replication in mammalian cells.Chromosoma 1979 Oct 1;74(3):347-53.
  7. Shepelev VA, Alexandrov AA, Yurov YB, Alexandrov IA, 2009 The Evolutionary Origin of Man Can Be Traced in the Layers of Defunct Ancestral Alpha Satellites Flanking the Active Centromeres of Human Chromosomes. PLoS Genet 5(9): e1000641. doi:10.1371/journal.pgen.1000641.
  8. Kaname T, McGuigan A, Georghiou A, Yurov Y, Osoegawa K, De Jong PJ, Ioannou P, Huxley C. Alphoid DNA from different chromosomes forms de novo minichromosomes with high efficiency. Chromosome Res 2005;13(4):411-22.
  9. Kazakov AE, Shepelev VA, Tumeneva IG, Alexandrov AA, Yurov YB, AlexandrovIA. Interspersed repeats are found predominantly in the "old" alpha satellite families. Genomics 2003 Dec;82(6):619-27.
  10. Alexandrov I, Kazakov A, Tumeneva I, Shepelev V, Yurov Y. Alpha-satellite DNA of primates: old and new families. Chromosoma 2001 Aug;110(4):253-66.
  11. Puechberty J, Laurent AM, Gimenez S, Billault A, Brun-Laurent ME, Calenda A, Marcais B, Prades C, Ioannou P, Yurov Y, Roizes G. Genetic and physical analyses of the centromeric and pericentromeric regions of human chromosome 5: recombination across 5cen.Genomics 1999 Mar 15;56(3):274-87.
  12. Mashkova T, Oparina N, Alexandrov I, Zinovieva O, Marusina A, Yurov Y,Lacroix MH, Kisselev L. Unequal cross-over is involved in human alpha satellite DNA rearrangements on a border of the satellite domain. FEBS Lett 1998 Dec 28;441(3):451-
  13. Vorsanova SG, Iurov IIu, Demidova IA, Voinova-Ulas VIu, Kravets VS, Solov'ev IV, Gorbachevskaia NL, Iurov IuB. [Variations of heterochromatic chromosomal regions and chromosome abnormalities in children with autism: identification of genetic markers in autistic spectrum disorders] Zh Nevrol Psikhiatr Im S S Korsakova 2006;106(6):52-7. Russian.
  14. Yurov YB, Vorsanova SG, Kolotii AD, Iourov IY. Molecular-cytogenetic investigation of skewed chromosome X inactivation in Rett syndrome. Brain Dev 2001 Dec;23 Suppl 1:S214-7.
  15. Vorsanova SG, Yurov YB, Ulas VY, Demidova IA, Sharonin VO, Kolotii AD,
  16. Gorbatchevskaia NL, Beresheva AK, Soloviev IV. Cytogenetic and molecular-cytogenetic studies of Rett syndrome (RTT): a retrospective analysis of a Russian cohort of RTT patients (the investigation of 57 girls and three boys). Brain Dev 2001 Dec;23 Suppl 1:S196-201.
  17. Vorsanova SG, Yurov YB, Kolotii AD, Soloviev IV. FISH analysis of replication and transcription of chromosome X loci: new approach for genetic analysis of Rett syndrome. Brain Dev 2001 Dec;23 Suppl 1:S191-5.
  18. Vorsanova SG, Demidova IA, Ulas VYu, Soloviev IV, Kazantzeva LZ, Yurov YuB. Cytogenetic and molecular-cytogenetic investigation of Rett syndrome: analysis of 31 cases.Neuroreport 1996 Dec 20;8(1): 187-9.
  19. Yurov YB, Vorsanova SG, Iourov IY. GIN'n'CIN hypothesis of brain aging: deciphering the role of somatic genetic instabilities and neural aneuploidy during ontogeny. Mol Cytogenet. 2009 Nov 25;2:23.
  20. Iourov IY, Vorsanova SG, Liehr T, Kolotii AD, Yurov YB: Increased chromosome instability dramatically disrupts neural genome integrity and mediates cerebellar degeneration in the ataxia-telangiectasia brain. Hum Mol Genet 2009, 18:2656-2669.
  21. Iourov, Y., Vorsanova, S.G., Liehr, T and Yurov, Y.B. Aneuploidy in the normal, Alzheimer’s disease and ataxia-telangiectasia brain: differential expression and pathological meaning. Neurobiol. Dis 2009, 34, 212-220.
  22. Iourov IY, Vorsanova SG, Yurov YB: Developmental neural chromosome instability as a possible cause of childhood brain cancers. Med Hypotheses 2009, 72:615-616.
  23. Iourov IY, Vorsanova SG, Soloviev IV, Yurov YB: Interphase FISH: detection of intercellular genomic variations and somatic chromosomal mosaicism. In Fluorescence in situ hybridization (FISH) – Application guide. Edited by Liehr T. Berlin, Heidelberg: Springer Verlag; 2009:301-311.
  24. Yurov, Y.B., Iourov, I.Y., Vorsanova, S.G., Demidova, I.A., Kravetz, V.S., , Beresheva, A.K., Kolotii, A.D., Monakchov, V.V., Uranova, N,A., Vostrikov, V.M. et al. The schizophrenia brain exhibits low-level aneuploidy involving chromosome 1. Schizophr Res 2008, 98, 137-147.
  25. Yurov YB, Iourov IY, Vorsanova SG, Liehr T, Kolotii AD, Kutsev SI, Pellestor F, Beresheva AK, Demidova IA, Kravets VS, Monakhov VV, Soloviev IV Aneuploidy and confined chromosomal mosaicism in the developing human brain. PLoS ONE 2007, 2:e558.
  26. Yurov YB, Vorsanova SG, Iourov IY, Demidova IA, Beresheva AK, Kravetz VS, Monakhov VV, Kolotii AD, Voinova-Ulas VY, Gorbachevskaya NL Unexplained autism is frequently associated with low-level mosaic aneuploidy. J Med Genet 2007, 44(8):521-535.
  27. Vorsanova S.G., Yurov Y.B., Iourov I.Y. Human interphase chromosomes: a review of available molecular cytogenetic technologies. // Molecular Cytogenetics. - 2010. – V.3. - №1. –Р.1-15.
  28. Vorsanova S.G., Voinova V.Yu., Yurov I.Yu., Kurinnaya O.S., Demidova I.A., Yurov Yu.B. Cytogenetic, molecular-cytogenetic, and clinical-genealogical studies of the mothers of children with autism: a search for familial genetic markers for autistic disorders. // Neuroscience and Behavioral Physiology. - 2010 - V.40. - №7. – P.745-756.
  29. Yurov I.Yu., Vorsanova S.G., Soloviev I.V., Yurov Yu.B. Methods of molecular cytogenetics for studying interphase chromosomes in human brain cells. // Russian journal of Genetics. – 2010 – V.46. - №9 – P.1039-1041.
  30. Yurov I.Yu., Vorsanova S.G., Soloviev I.V., Yurov Yu.B. Instability of chromosomes in human nerve cells (normal and with neuromental diseases). // Russian journal of Genetics. – 2010 – V.46. - №10 – P.1194-1196.
  31. Vorsanova S.G., Iourov I.Y., Kolotii A.D., Beresheva A.K., Demidova I.A., Kurinnaya O.S., Kravets V.S., Monakhov V.V., Soloviev I.V., Yurov Y.B. Chromosomal mosaicism in spontaneous abortions: analysis of 650 cases. // Russian journal of Genetics. – 2010 – V.46. - №10 – P.1197-1200.
  32. Iourov I.Y., Vorsanova S.G., Saprina E.A., Yurov Yu.B. Identification of candidate genes of autism on the basis of molecular cytogenetic and in silico studies of the genome organization of chromosomal regions involved in unbalanced rearrangements. . // Russian journal of Genetics. – 2010 – V.46. - №10 – P.1190-1193.
  33. Iourov I.Y., Vorsanova S.G., Yurov Yu.B. Somatic genome variations in health and disease. // Current Genomics. – 2010. V.11. – N6. – P387-396.
  34. Yurov Y.B., Vorsanova S.G., Iourov I.Y. Ontogenetic variation of the human genome.// Current Genomics. – 2010. V.11. – N6. – P420-425.
  35. Vorsanova S.G., Yurov Y.B., Soloviev I.V., Iourov I.Y. Molecular cytogenetic diagnosis and somatic genome variations. .// Current Genomics. – 2010. V.11. – N6. – P440-446.
  36. Iourov IY, Vorsanova SG, Yurov YB. Genomic Landscape of the Alzheimer's Disease Brain: Chromosome Instability - Aneuploidy, but Not Tetraploidy - Mediates Neurodegeneration. Neurodegener Dis. 2011;8(1-2):35-37.
  37. Vorsanova S.G., Iourov I.Y., Soloviev I.V., Yurov Y.B. Heterochromatic regions of human chromosomes: clinical and biological aspects. MedPraktika, Moscow, 2008.
  38. Vorsanova S.G., Yurov Y.B., Chernyshov V.N. (eds) Medical Cytogenetics. MedPraktika, Moscow, 2006.

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Last Updated: August, 2012.

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