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Biography
AA

Dr. Anshu Agrawal

Department of Medicine

University of California, USA


Email: aagrawal@uci.edu


Qualifications

1994 Ph.D., Biochemistry, Lucknow University, India

1988 M.Sc., Biochemistry, Lucknow University, India

1986 B.Sc., Chemistry, Botany, Zoology, Lucknow University, India


Publications (selected)

  1. Sridharan A, Esposo M, Kaushal K, Tay J, Osann K, Agrawal S, Gupta S,Agrawal A.Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity.AGE. 2010. (in press).DOI: 10.1007/s11357-010-9191-3.
  2. Agrawal S, Gupta S andAgrawal A.Human dendritic cells activated via Dectin-1 are efficient at priming Th17, cytotoxic CD8 T and B cell responses.PLoS One. 2010 Oct 18;5(10):e13418.
  3. Agrawal Aand Gupta S. Impact of aging on dendritic cell functions in humans. Ageing Research Reviews. 2010. Accepted.
  4. Agrawal A,Tay J, Yang GE, Agrawal S, Gupta S. Age-associated epigenetic modifications in human DNA increases its immunogenicity.Aging.2010.Jan10. Epub ahead of print. NIHMSID-176388.
  5. Carlson ME, Conboy MJ, Hsu M, Barchas L, Jeong J, Agrawal A, Mikels AJ, Agrawal S, Schaffer DV, Conboy IM. Relative roles of TGF-beta1 and Wnt in the systemic regulation and aging of satellite cell responses.Aging Cell.2009. 8(6):676-89.
  6. Gu B, Sun P, Yuan Y, , Moraes RC, Li A, Teng A,Agrawal A, Rhéaume C, Bilanchone V, Veltmaat JM, X.*Takemaru KI, Millar S, Lee EYHP, Lewis MT, Li B and DaiPygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation.Journal of Cell biology. 2009. 185: 811-826.
  7. Agrawal A,Tay J, Ton S, Agrawal S, Gupta S.Increased Reactivity of Dendritic Cells from Aged Subjects to Self Antigen, the Human DNA.J Immunol. 2009. 182: 1138-1145.
  8. Agrawal S,Gupta S,Agrawal A.  Vaccinia Virus Proteins Activate Human Dendritic Cells to Induce T Cell Responses in vitro.Vaccine.2009. 27:88-92.
  9. Agrawal A.How Aging impacts innate immunity. New Research on Innate Immunity.2008. (Nova Publishers).63-72.
  10. Agrawal A,Lourenco EV, Gupta S, La Cava A. Gender-based differences in leptinemia in healthy aging, non-obese individuals associated with increased marker of oxidative stress.Int J Clin Exp Med.2008.1 : 305-309.
  11. Agrawal A,Agrawal S, Tay, J, Gupta S. Biology of Dendritic Cells in Aging.J Clin. Immunol. 2008. 28: 14-20.
  12. Agrawal A, Agrawal S, Cao J, Su H, Osann K, Gupta S. Altered innate immune functioning of dendritic cells in aging humans : Role of PI3Kinase signaling pathway.J Immunol. 2007.178:6912-6922.
  13. Agrawal A, Kaushal P, Agrawal S, Gollapudi S, Gupta S. Thimerosal affects human dendritic cell functions promoting a TH2 response.J Leukocyte Biology. 2007. 81: 474-483.
  14. Agrawal A, Agrawal S, Gupta, S. Dendritic cells in human aging.Experimental Gerontology. 2006. 42(5): 421-426.
  15. Agrawal A, Dillon S, Denning TL, and Pulendran B. ERK1-/- mice exhibit Th1 cell polarization and increased susceptibility to Experimental Autoimmune Encephalomyelitis.J Immunol. 2006. 176: 5788 - 5796.
  16. Gupta S,Agrawal A, Agrawal S, Su H and Gollapudi S. A paradox of immunodeficiency and inflammation in aging: Lessons learned from apoptosis.Immunity & Ageing. 2006. 3:5.
  17. Nair M, Teng A, Bilanchone V,Agrawal A, Li B, and Dai X.Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-Myc transcription. Journal of Cell biology.2006. 173: 253-264.
  18. Sharma, SK., Deba, F., Bhattachrya, S.,Agrawal, A., Owais, M. Escheriosome entrapped soluble blood stage antigens impart protective immunity against a multi-drug resistant isolate of Plasmodium yoelii nigeriensis in BALB/c mice.Vaccine. 2006. 7:948-956.
  19. Pulendran B ,Agrawal A, Dillon S , Agrawal S. Dendritic cells: Target of Immune Modulation by Microbes and Immunologist.Vaccine Adjuvants -Immunological and Clinical Principles.2005.25-38.(Humana Press).
  20. Agrawal AandPulendran B. Anthrax lethal toxin: a weapon of multisystem destruction.Cell Mol Life Sci. 2004 61(22):2859-65.


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